22 results about "Leonurus japonicus" patented technology

The invention provides a traditional Chinese medicine composition for treating chronic kidney diseases and a preparation method and application thereof, and belongs to the field of traditional Chinese medicines. The traditional Chinese medicine composition is prepared from the following raw material medicines in parts by weight: 16 to 24 parts of astragalus membranaceus, 24 to 36 parts of poria cocos, 24 to 36 parts of motherwort herb, 16 to 24 parts of herba pyrolae, 24 to 36 parts of hairyvein agrimony, 24 to 36 parts of herba ardisiae japonicae, 16 to 24 parts of dianthus superbus, 16 to 24 parts of cluster mallow fruit and 6.4 to 9.6 parts of tetrapanax papyriferus. The invention further provides a preparation method and application of the traditional Chinese medicine composition. The traditional Chinese medicine composition disclosed by the invention can safely and effectively improve the renal function of patients suffering from chronic kidney diseases such as qi deficiency, blood stasis and damp turbidity accumulation, relieve clinical symptoms and delay disease progression, and a traditional Chinese medicine scheme with an exact curative effect is provided for clinically treating the diseases.

The invention belongs to the field of bone nutrition powder, and particularly relates to bone nutrition powder for assisting in relieving arthritis pain and a preparation process. In the preparation, the herba eupatorii extract and the kelp extract are matched to effectively improve the arthritis pain relieving effect of the preparation, and the lophatherum gracile, the raspberry, the motherwort and the purslane are adopted to further improve the arthritis pain relieving effect of the fermented product through the processes of fermentation and the like; the preparation is applied to preparation of the bone nutrition powder, and the bone nutrition powder for assisting in relieving arthritis pain is prepared from the bone nutrition powder, protein, fat, water-soluble dietary fibers, vitamins, mineral elements and chondroitin sulfate. The obtained bone nutrition powder can effectively provide nutrition, also has an excellent health care effect, assists in relieving arthritis pain, and is excellent in performance and relatively good in application prospect.

This invention discloses a kidney-tonifying and blood-activating traditional Chinese medicine composition and its application in improving postoperative visual function, belonging to the field of pharmaceutical technology. The kidney-tonifying and blood-activating traditional Chinese medicine composition of this invention is made from 10 parts of Cuscuta chinensis, 15 parts of Broussonetia papyrifera fruit, 18 parts of Lycium barbarum, 15 parts of Leonurus japonicus, 20 parts of Leonurus japonicus, 10 parts of Ligusticum chuanxiong, 9 parts of Prunus persica kernel, 6 parts of Carthamus tinctorius, 15 parts of Poria cocos, 18 parts of Albizia julibrissin bark, 12 parts of Astragalus membranaceus, and 12 parts of Pueraria lobata root. It can be standardized and adjusted according to clinical complications. This invention focuses on the critical point of "kidney deficiency and blood stasis" one month after posterior scleral reinforcement surgery, using the principles of tonifying the liver and kidneys and activating blood circulation to improve ocular microcirculation, enhance and stabilize vision, thereby protecting visual function, and conforming to the treatment principle of "treating the root cause when the condition is mild."

The present application relates to the field of traditional Chinese medicinal materials, in particular to a composition for resisting PRRSv and improving the reproductive performance of sows and application thereof. The present application formulates a composition composed of 10 plant extracts (Angelica sinensis extract, Atractylodes macrocephala Koidz extract, Glycyrrhiza uralensis Fisch extract, Eucommia ulmoides Oliver extract, Eucommia ulmoides leaf extract, Populus davidiana Dode extract, Perilla frutescens leaf extract, Gynostemma pentaphyllum Makino extract, Leonurus japonicus extract and Astragalus membranaceus Bge extract) for sows in late pregnancy, and collects sow blood and placenta samples at the time of delivery, studies the influence of the composition on sow reproduction, and explores the mechanism of action. The experimental results show that the composition can improve the reproductive performance of sows by increasing the total number of piglets and other indicators; meanwhile, the composition can effectively inhibit the replication of PRRSv.

The invention relates to the field of repair product preparation, in particular to a novel nano-antibacterial skin repair product for preventing hpv viruses. The formula is prepared from the following raw materials by weight: 0.80 to 4.50 g of purified water, 0.008 to 0.150 g of carbomer, 0.01 to 0.80 g of fenugreek oil, 0.01 to 0.30 g of oat beta glucan, 0.003 to 0.400 g of folium artemisiae argyi extracting solution, 0.01 to 0.40 g of herba portulacae extracting solution, 0.006 to 0.420 g of herba violae extracting solution, 0.001 to 0.200 g of herba lophatheri extracting solution, 0.007 to 0.300 g of herba taraxaci extracting solution, 0.008 to 0.220 g of rhizoma paridis chinensis extracting solution, 0.01 to 0.40 g of herba leonuri extracting solution, 0.0005 to 0.0300 g of nano silver and 0.008 to 0.150 g of borneol. The adhesive comprises the following components by weight: 0.01 to 0.30 g of sodium carboxymethyl cellulose, 0.008 to 0.220 g of lubrajel, 0.007 to 0.300 g of benzoyl peroxide, and 0.0005 to 0.0300 g of a cross-linking agent. The invention has the following beneficial effects: the ointment comprises a plurality of plant extracts, has no irritation to vagina, is safe and has no side effect; the carried antiviral and antibacterial components can rapidly permeate into the skin to protect mucous membrane cells from being damaged by viruses; skin tissues can be quickly repaired, and wound healing and regeneration capacity is improved; various plant extracts in the gel can also improve the immunity of the organism and can achieve a good antiviral effect.

The invention belongs to the technical field of traditional Chinese veterinary medicines, and particularly relates to a traditional Chinese medicine compound for improving the egg laying performance of laying hens and a preparation method and application of the traditional Chinese medicine compound for improving the egg laying performance of the laying hens, and the traditional Chinese medicine compound comprises codonopsis pilosula, astragalus membranaceus, angelica sinensis, rhizoma atractylodis macrocephalae, herba epimedii, leonurus japonicus, fructus lycii, actinolite, rhizoma cyperi and berberine. The ratio of codonopsis pilosula to astragalus membranaceus to angelica sinensis to atractylodes macrocephala koidz to herba epimedii to leonurus japonicus to fructus lycii to actinolite to rhizoma cyperi to berberine is 2: 2: 1: 1: 3: 3: 1: 2: 1: 1. The traditional Chinese medicine compound for improving the egg laying performance of the laying hens and the preparation method and application thereof have the beneficial effects that by setting and selecting the ratio, the effectiveness and pertinence of a compound preparation can be ensured, and the effect of improving the egg laying performance of the laying hens is achieved. The method helps to improve the egg laying performance of laying hens, reduces unnecessary side effects, and can extract effective components in the traditional Chinese medicines and remove impurities by setting the extraction step. The quality and purity of the traditional Chinese medicine compound preparation can be guaranteed, and the medicine effect is improved.

This invention relates to the technical field of aquaculture feed, specifically a special nutritional feed for laying female turtles, comprising the following ingredients by weight: 45-60% Cordyceps militaris mycelium, 20-25% wheat bran, 12-15% corn flour, 5-10% tomato powder, and 3-5% oyster meat powder. The Cordyceps militaris mycelium is obtained by mixing a culture medium containing 35-50% soybean meal, 20-25% sugarcane, 15-20% Leonurus japonicus, 8-10% oyster shell powder, 5-7% soybean flour, and 2-3% silkworm pupa powder with lotus root sauce, placing it evenly in a cultivation box, sterilizing it, and then inoculating and cultivating it. The inoculum is isolated from the fruiting bodies of Cordyceps militaris and then cultivated into a liquid inoculum. This special nutritional feed for laying female turtles has a cleverly formulated ingredient ratio, achieving multiple goals such as enhancing immunity, supplementing ovulation nutrition, improving reproductive performance, preventing postpartum inflammation, and shortening the recovery period. Furthermore, this feed is highly safe and free of drug residues.

The invention belongs to the technical field of liquid phase detection, and particularly relates to a wine antifebrile dichroa quality control and detection method. According to the detection method, high performance liquid chromatography is adopted to detect the content of dichroine in a solution in a test sample, and specific chromatographic conditions are as follows: a mobile phase A is acetonitrile, a mobile phase B is an acetic acid aqueous solution with the volume fraction of 0.15-0.35%, and the pH value of the mobile phase B is adjusted to 5.5-6.5 by using triethylamine; a chromatographic column takes octadecylsilane chemically bonded silica as a stationary phase, and the detection wavelength is 223 to 227 nm. The detection method disclosed by the invention has a good linear relationship when the concentration of the febrifugine is 0.67 mu g / mL to 66.64 mu g / mL; the sensitivity is high, the precision is high, and the detection limit is lt; the concentration is 0.36 mu g / mL, and the quantification limit is 1t; 0.90 [mu] g / mL; the repetitive stability is high; the sample recovery rate is high, and the average recovery rate of the dichroine hydrochloride reference substance is more than 90%.

The present application belongs to the field of biological medicine, and relates to a traditional Chinese medicine composition for treating chronic heart failure. The traditional Chinese medicine composition comprises the following traditional Chinese medicinal materials or is prepared based on raw medicinal materials comprising the following traditional Chinese medicines: Astragalus membranaceus (Fisch.) Bunge, Acanthopanax senticosus, black ginseng, Leonurus japonicus Houtt., Ophiopogon japonicus (Thunb.) Ker-Gawl., Eutrema latifolium, Schisandra chinensis (Turcz.) Baill., Cinnamomum cassia Presl and Polygonatum sibiricum. Clinical test results show that the traditional Chinese medicine composition significantly increases the systolic pressure and diastolic pressure of heart failure patients when treating chronic heart failure patients, not only has a significant effect, but also has a rapid effect. In addition, the traditional Chinese medicine composition significantly reduces the degree of cardiac inflammation and significantly improves the cardiac function in an experimental autoimmune myocarditis mouse model. In an adriamycin-induced heart failure model SD rat, the traditional Chinese medicine composition also significantly improves the cardiac function, showing good treatment potential.

The invention relates to a traditional Chinese medicine composition for improving hypomenorrhea and application thereof, and belongs to the technical field of biological medicine. The herba leonuri, the anisodamine and the Dingkundan are combined to form the composition, efficacy complementation can be achieved, it is guaranteed that the medicine takes effect quickly, the long-acting treatment effect is maintained, meanwhile, the side effect caused by long-term single medication is avoided, the treatment safety and tolerance are improved, the menstrual volume can be remarkably increased, endometrial blood circulation can be improved, and the curative effect is improved. The hypomenorrhea is effectively improved. The medicines in the composition are all approved compliant medicines, the source is clear, the quality is controllable, the administration scheme is simple and easy to implement, the composition is suitable for clinical popularization and application, and a novel safe, efficient and reproducible treatment method is provided for hypomenorrhea.

The invention discloses a radix sophorae flavescentis composite traditional Chinese medicine preparation for reducing soft-shell eggs and sand-preserved eggs of laying hens as well as a preparation method and application thereof, and relates to the technical field of traditional Chinese medicine preparations. The radix sophorae flavescentis composite traditional Chinese medicine preparation is prepared by mixing radix sophorae flavescentis, radix astragali, herba epimedii, herba leonuri, pine needles, chestnut shells and licorice roots to serve as a traditional Chinese medicine composition, adopting lactobacillus plantarum, lactobacillus cellobiosus and bacillus lentus as fermentation bacteria liquid, inoculating the traditional Chinese medicine composition with the composite fermentation bacteria liquid, and conducting fermentation, drying and smashing. Through cooperation of the traditional Chinese medicine composition and the zymophyte liquid, the production of soft-shell eggs and sand-preserved eggs can be reduced. In addition, the lactobacillus plantarum, the lactobacillus cellobiosus and the bacillus lentus are combined to serve as the zymophyte liquid, and the zymophyte liquid has a synergistic effect on reducing soft-shell eggs and sand-preserved eggs laid by the laying hens.

This invention provides a topical composition and its preparation method for reversing gray hair to black and repairing the scalp. The topical composition comprises the following raw materials in parts by weight: 10-30 parts of Polygonum multiflorum, 10-25 parts of Platycladus orientalis leaves, 8-20 parts of Artemisia argyi, 5-15 parts of ginger, 5-15 parts of Morus alba root bark, 5-12 parts of Leonurus japonicus, 5-12 parts of Lycium chinense root bark, 3-10 parts of Angelica dahurica, 5-15 parts of Morus alba leaves, 5-12 parts of Citrus reticulata peel, 3-10 parts of tea leaves, 3-10 parts of Auricularia auricula-judae, and 2-8 parts of Glycyrrhiza uralensis. The topical composition also contains a compound plant extract, which is obtained by alcohol extraction from Acer palmatum, Paederia scandens, and Areca catechu flowers in a mass ratio of (2.8-3.2):(0.9-1.1):(1.5-2.5). The composition of this invention can activate scalp tyrosinase activity and promote melanin production; improve scalp microcirculation and hair follicle nutrient supply; repair damaged hair and delay gray hair growth; achieve root-cause promotion of gray hair turning black, and also has scalp care function to restore black and shiny hair.

The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating chronic cerebral circulation insufficiency. The traditional Chinese medicine composition comprises the following components: gastrodia elata, desert cistanche, lucid ganoderma, fructus broussonetiae, fructus lycii, rhodiola rosea, semen cuscutae, tribulus terrestris, pseudo-ginseng and motherwort fruit. The traditional Chinese medicine composition can effectively solve the problems of large side effects and limited curative effects of existing western medicine treatment, adopts natural traditional Chinese medicine components, does not have obvious toxic or side effects, can realize consideration of both symptoms and root causes from the pathogenesis of'deficiency in root and excess in superficies', avoids the problems of gastrointestinal tract injury, liver and kidney function injury and the like caused by long-term administration of western medicine, has a more lasting curative effect and is not easy to relapse; the problems that an existing traditional Chinese medicine formula is single and poor in synergistic effect are solved, the limitation of single blood circulation promoting and blood stasis removing is broken through, a multi-target-point formula system is constructed through kidney tonifying, essence replenishing, blood circulation promoting and blood stasis removing, qi tonifying, nerve soothing, liver calming and collateral dredging, all the components achieve the synergistic effect, the disease pathogenesis is comprehensively matched, and the medicine effect is stable and remarkable.

The application discloses a Talaromyces purpureogenus and application thereof in weeding, and belongs to the technical field of bioengineering and weeding, wherein the Talaromyces purpureogenus is named as CY-1, is preserved in the China General Microbiological Culture Collection Center, and has a preservation date of May 23, 2022 and a preservation number of CGMCC No.40203. Metabolic products of the Talaromyces purpureogenus CY-1 in the application can effectively inhibit broadleaf weeds such as amaranthus retroflexus, alternanthera philoxeroides, xanthium, chenopodium album, solanum nigrum, bidens pilosa, comphre, sonchus oleraceus, pteris cretica, medicago sativa, ipomoea hederifolia, rumex patientia, galium aparine, abutilon theophrasti, portulaca oleracea, leonurus japonicus, veronica anagallis, and aster spathulifolius, and the Talaromyces purpureogenus CY-1 is green and efficient in weeding, and has a wide application prospect in weeding.

This invention belongs to the field of traditional Chinese medicine and natural product technology, specifically relating to the use of Leonurus japonicus extract in the preparation of antidepressant drugs. This invention uses 70% ethanol extraction to prepare Leonurus japonicus extract. This extraction method reduces extraction costs, shortens production time, increases extract yield, increases the extraction rate of effective components, and increases enterprise production efficiency. This invention also uses multiple depression models to verify the antidepressant activity of Leonurus japonicus extract, including a chronic unpredictable mild stress-induced depression model, a chronic corticosterone injection-induced depression model, and an ovariectomy combined with hormone withdrawal-induced depression model. The results show that Leonurus japonicus extract has a significant antidepressant effect in experimental animals. The antidepressant effect of the Leonurus japonicus extract of this invention is not obvious compared to the characteristics of traditional gynecological drugs, and it focuses on hormone-related depression, demonstrating the therapeutic value of Leonurus japonicus extract in the clinical classification of depression.

This application proposes a method for establishing a rapid propagation system for Leonurus japonicus, comprising: inoculating pretreated and sterilized Leonurus japonicus explants onto a callus induction medium for primary culture; after obtaining stable callus tissue from the primary culture, placing the callus tissue into an adventitious bud culture medium to cultivate adventitious buds; once the adventitious buds have grown, placing them into a rooting medium to root, thereby obtaining Leonurus japonicus seedlings suitable for rapid planting. Using this method, the success rate of callus induction can be improved, achieving a Leonurus japonicus callus induction rate >95%, and Leonurus japonicus callus tissue conducive to adventitious bud proliferation and rooting can be obtained, thus establishing a complete and stable rapid propagation system for Leonurus japonicus. This method can significantly shorten the growth cycle of Leonurus japonicus, enabling rapid propagation to meet market demand and providing a technological foundation for the large-scale production of Leonurus japonicus.

The application provides application of breast milk-derived stem cells combined with umbilical cord mesenchymal stem cells in preparation of a drug for treating premature ovarian failure, and belongs to the technical field of biological medicine. The application also provides a stem cell preparation for treating premature ovarian failure, which comprises breast milk-derived stem cells, umbilical cord mesenchymal stem cells, resveratrol glycoside, melatonin, Leonurus japonicus glycoside, vitamin C, human blood albumin and physiological saline. The breast milk-derived stem cells and the umbilical cord mesenchymal stem cells play a core role, promote follicle survival and regeneration, and improve the pathological state of ovarian ischemia and hypoxia; the Leonurus japonicus glycoside can assist in dredging and improving local microcirculation; the vitamin C, the melatonin and the resveratrol glycoside can remove excessive harmful free radicals in the ovary and the whole body, and curb the continuous damage of oxidative stress to the follicle. Animal experiments show that the stem cell preparation can significantly improve the serum hormone level of premature ovarian failure mice, increase the reserve and competence of follicles at all levels, and has a clear repairing effect on ovarian function.

This invention discloses a traditional Chinese medicine composition for treating high myopia, which is made from the following raw materials: Astragalus membranaceus, Angelica sinensis, Rehmannia glutinosa, Chaenomeles speciosa, Bupleurum chinense, Paeonia lactiflora, Cuscuta chinensis, Leonurus japonicus, and Glycyrrhiza uralensis. Clinical studies have demonstrated that this traditional Chinese medicine composition has a significant therapeutic effect on macular degeneration in high myopia.

The application provides application of UGT5 genes and SCPL12 genes in production of agrostemma herb base in hairy roots. The application is realized by designing primer compositions to amplify the UGT5 genes and the SCPL12 genes, constructing a recombination carrier by using a Gateway technology, transforming the recombination carrier into Agrobacterium rhizogenes to obtain an Agrobacterium rhizogenes strain containing the UGT5 and the SCPL12, infecting leaves of Leonurus japonicus by using the Agrobacterium rhizogenes strain, culturing to obtain transgenic Leonurus japonicus hairy roots, and further producing the agrostemma herb base in the hairy roots. The content of the agrostemma herb base in the hairy roots of Leonurus japonicus obtained by using the Agrobacterium rhizogenes mediation and simultaneously overexpressing the UGT5 and the SCPL12 is higher than that of a control group. The method lays a foundation for production of the agrostemma herb base in transgenic plant cells.

The invention relates to the technical field of poultry breeding, in particular to application of a traditional Chinese medicine compound bacterium preparation to improvement of laying performance of laying hens and egg quality. The invention provides a composition for improving the production performance and egg quality of laying hens. The composition is prepared from radix astragali, radix fici simplicissimae, herba leonuri, herba artemisiae scopariae, fructus citri sarcodactylis and a complex microbial inoculant. In the composition, astragalus membranaceus serves as a monarch drug, radix fici simplicissimae serves as a ministerial drug, fingered citron and oriental wormwood serve as adjuvant drugs, and motherwort serves as a conductant drug. The composition provided by the invention not only accords with the traditional Chinese medicine idea of combining body resistance strengthening (qi tonifying and spleen strengthening) and evil eliminating (heat clearing, dampness eliminating, qi regulating and blood activating), but also pertinently solves the core problems of deficiency of qi and blood, weakness of the spleen and the stomach, damp heat and qi stagnation and the like in the laying period of laying hens, and finally achieves the goal of improving the production performance and the egg quality.

The invention belongs to the technical field of traditional Chinese medicine quality control methods, and relates to a motherwort herb quality control method. According to the method, a reference medicinal material is taken as a reference, a characteristic chromatogram is constructed, representative components capable of representing motherwort herb are selected as characteristic peaks, and the authenticity of motherwort herb is judged by comparing the quantity and relative retention time of the characteristic peaks with the quantity and relative retention time of the characteristic peaks of the tested medicinal material. In the quantitative link, hyperoside which is stable in retention time, low in price and easy to obtain is selected as a quantitative index, chemical component relative quantitative research based on the characteristic peak is carried out, and the relative content of chemical components of other characteristic peaks of the tested medicinal material is calculated by accurately quantifying the hyperoside. The peak areas of 13 characteristic peaks of a test sample are used as input information, and intelligent similarity is calculated through double-layer fusion of'basic similarity + machine learning similarity 'so as to evaluate the similarity of a test medicinal material and a reference medicinal material, so that comprehensive quantitative evaluation of quality is realized. The method provides a simple, convenient and economical new scheme for motherwort quality control.

The invention discloses an anti-hair-loss and oil-control composite liquid with a synergistic effect as well as a preparation method and application of the anti-hair-loss and oil-control composite liquid. The compound liquid comprises a plurality of plant active ingredients such as cacumen biotae extract, fructus forsythiae fruit extract, motherwort extract, withanthemum sinensis root extract, polygonum multiflorum extract, ginger root extract, aster extract, ginseng root extract, white willow bark extract and the like, the synergistic interaction effect is achieved through scientific proportioning, and the anti-hair-loss and oil-control effects are remarkably enhanced. The compound liquid can be added into hair washing and caring products, the adding amount of the compound liquid is 0.1-10% of that of resident products, and the adding amount of the compound liquid is 0.1-20% of that of drip washing products. Experiments prove that the anti-hair-loss and oil-control effects of the compound liquid are obviously better than those of a single plant extract and commercially available like products.