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A kind of medical restoration coating agent and preparation method thereof

A technology of coating agent and bacteriostatic agent, which is applied in the field of medical repair coating agent and its preparation, can solve the problems of lack of good physical isolation properties, easy infection or pollution of the affected area, and shorten application time, so as to achieve good protection and Treatment effect, adjuvant therapy for scarring, effect of increasing utilization

Active Publication Date: 2020-05-08
HARBIN QIANBAINA BIOPHARM
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] That is to say, ointments and gels generally use ointment base or gel base to load drugs and apply them to the affected area to play a therapeutic role. Due to the existence of the base, they will not dry under normal circumstances and are easy to be damaged during artificial contact with the outside world. Wipe off, thereby reducing the application time, and because it does not have good physical isolation properties, the affected area is easy to be infected or polluted during use
Composite material dressings in the field of medical materials often have shortcomings in adaptability, application time and tightness due to their poor conformability and hard film quality

Method used

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  • A kind of medical restoration coating agent and preparation method thereof
  • A kind of medical restoration coating agent and preparation method thereof
  • A kind of medical restoration coating agent and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0062] A medical repair coating agent, which is made of the following components: polyvinyl alcohol 1788 5%, polyvinyl alcohol 05883%, carbomer 9400.5%, sodium hyaluronate with a molecular weight of 2500-3000kDa 0.3%, a molecular weight 200-400kDa sodium hyaluronate 0.1%, molecular weight 5-10kDa sodium hyaluronate 0.1%, Scutellaria baicalensis root extract 1%, Salvia miltiorrhiza extract 0.2%, glycerin 5%, propylene glycol 1%, allantoin 0.2 %, Sodium Methylparaben 0.05%, Sodium Propylparaben 0.02%, Sodium Benzoate 0.1%, Polysorbate 805%, Glyceryl Caprylate 1%, Caroxane 2%, Shea Butter 1%, The balance is purified water.

[0063] In the present embodiment, the extraction process of the root extract of Scutellaria baicalensis comprises the following steps:

[0064] 1) Scutellaria baicalensis crude drug was taken, sliced, crushed to pass through a 20-mesh sieve, added purified water equivalent to 10 times the weight of baicalin baicalensis, soaked for 2 hours, heated to 100°C, d...

Embodiment 2

[0074] A kind of medical restoration coating agent, it is made of following each component:

[0075] Polyvinyl alcohol 1788 12%, xanthan gum 0.5%, sodium hyaluronate with a molecular weight of 2500-3000kDa 0.3%, sodium hyaluronate with a molecular weight of 200-400kDa 0.2%, sodium hyaluronate with a molecular weight of 5-10kDa 0.1 %, Scutellaria baicalensis root extract 0.5%, Salvia miltiorrhiza extract 0.3%, Trimethylglycine 0.2%, Glycerin 3%, Hexylene glycol 0.5%, Butylene glycol 2%, p-Hydroxyacetophenone 0.5%, Polysorbate 60 2%, glyceryl caprylate 1%, polydimethylsiloxane 2%, and the balance is purified water.

[0076] The preparation process of the Scutellaria baicalensis root extract and the Salvia miltiorrhiza extract described in this example are the same as in Example 1.

[0077] The preparation process of the coating agent described in this embodiment is the same as that in Example 1.

Embodiment 3

[0079] A kind of medical restoration coating agent, it is made of following each component:

[0080] Polyvinyl alcohol 0588 18%, hydroxyethyl cellulose 0.5%, tara gum 0.5%, glycerin 6%, sodium hyaluronate with a molecular weight of 200-400kDa 0.1%, sodium hyaluronate with a molecular weight of 5-10kDa 0.3 %, Glucosamine 0.5%, Scutellaria Root Extract 0.5%, Salvia Miltiorrhiza Extract 0.3%, Sodium Methylparaben 0.03%, Sodium Benzoate 0.1%, Polysorbate 802%, Polysorbate 20 2%, Vitamin E 1% , jojoba oil 1%, and the balance is purified water.

[0081] The preparation process of the Scutellaria baicalensis root extract and the Salvia miltiorrhiza extract described in this example are the same as in Example 1.

[0082] The preparation process of the coating agent described in this embodiment is the same as that in Example 1.

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Abstract

The invention belongs to the technical field of coating agents and particularly relates to a medical repair coating agent and a preparation method thereof. The coating agent is prepared from 8-35% ofa biological adhesive material, 3-18% of a plasticizer, 0.1-5% of active substances, 0.05%-0.5% of a bacteriostatic agent, 0.5-10% of an emulsifier, 0.5-8% of grease and the balance purified water, wherein the effective substances are at least one of micromolecule sodium hyaluronate, scutellaria root extract, salvia miltiorrhiza extract, trimethylglycine, allantoin and glucosamine. The coating agent is short in film-forming time, good in ductility and easy to apply, and a film formed after application has good toughness without cracking, tearing and the like; the adhesion property of the filmis proper, when the film is removed at the end of action, the comfort is high, and the conditions of skin pain, secondary wound cracking and the like in the pulling process are avoided.

Description

technical field [0001] The invention belongs to the technical field of coating agents, and in particular relates to a medical restoration coating agent and a preparation method thereof. Background technique [0002] With the improvement of people's living standards, people pay more and more attention to the maintenance of appearance. Cosmetics, as a means of skin maintenance, are used by more and more people. However, due to market misleading or improper use of skin care products, causing People, especially teenagers, have excessive skin care behaviors, such as excessive cleaning, excessive application of masks to cause excessive skin hydration, excessive exfoliation of the stratum corneum, resulting in too thin stratum corneum, etc., resulting in a certain degree of damage to the skin barrier, while the skin barrier structure and Dysfunction is associated with a variety of skin problems. [0003] The skin barrier is mainly composed of stratum corneum, structural lipids and...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/70A61K36/539A61P17/02A61P17/10A61P17/00A61K31/728A61K31/198A61K31/4166A61K31/7008
CPCA61K9/0014A61K9/7015A61K31/198A61K31/4166A61K31/7008A61K31/728A61K36/537A61K36/539A61P17/00A61P17/02A61P17/10A61K2300/00
Inventor 高纳新
Owner HARBIN QIANBAINA BIOPHARM
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