Unlock instant, AI-driven research and patent intelligence for your innovation.

Cell delivery system and methods of operation thereof

A technology of cells and syringes, which is applied in the direction of medical formulations, drug devices, and devices introduced into the body, etc., and can solve problems such as cell damage, needle path blockage, and inconsistent treatment results

Pending Publication Date: 2019-10-25
SANBIO
View PDF31 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, using a needle to withdraw such a high concentration of cells can lead to blockage of the needle path, which in turn can lead to cell damage and inconsistent treatment outcomes

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Cell delivery system and methods of operation thereof
  • Cell delivery system and methods of operation thereof
  • Cell delivery system and methods of operation thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0032] Figure 1A A syringe 100 shown for transplanting or implanting cells may include a plunger 102 , a barrel 104 and a hub 106 . Barrel 104 may be shaped as an elongated cylindrical tube. The barrel 104 can have a proximal barrel end 114 , a distal barrel end 116 , and a cavity 118 between the proximal barrel end 114 and the distal barrel end 116 . In one variation, barrel 104 may be constructed of or include a ceramic material such as borosilicate glass or the like. In other variations, the barrel 104 may be constructed of or include a polymer such as polytetrafluoroethylene (PTFE).

[0033] In one variation, the outer diameter of the barrel 104 may range from about 6.00 mm to 10.00 mm. The inner diameter of the barrel 104 may range from about 1.25 mm to 5.00 mm.

[0034] Needle hub 106 may be coupled to barrel 104 at barrel distal end 116 and includes a mating connector 120 capable of receiving and securing a needle 124 . The hub 106 may be a locking hub and may be m...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

A method of preparing a syringe in connection with a therapeutic treatment is disclosed. The method can include removing a plunger of the syringe from a barrel of the syringe, aligning the barrel in ahorizontal orientation, filling a lumen of the barrel with a viscous material through an opening at a proximal end of the barrel, and inserting a plunger tip into the lumen to seal the lumen. The method can also include attaching an implantation device to a hub coupled to the barrel at a distal end of the barrel. The method can also include depressing the plunger until the cell suspension fills the implantation device and a droplet of the cell suspension is expelled from a distal tip of the implantation device.

Description

[0001] Cross References to Related Applications [0002] This application claims the benefit of U.S. Provisional Application No. 62 / 439,818, filed December 28, 2016, the contents of which are hereby incorporated by reference in their entirety. technical field [0003] The present disclosure relates generally to the field of cell delivery, and more particularly, to a cell delivery system for delivering a high viscosity cell suspension to a subject in connection with therapeutic treatment. Background technique [0004] Stem cell transplantation is a novel therapeutic treatment that relies on the delivery of living cells to target sites to restore damaged tissue function. Stem cell transplantation has shown potential to treat neurological diseases and injuries such as stroke, Parkinson's disease, traumatic brain injury, paralysis, and peripheral arterial disease. A common transplant procedure involves injecting stem cells directly into the patient. Such procedures often requi...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61M5/14A61M5/178A61M5/31
CPCA61M5/31531A61M2209/088A61M5/36A61M5/1782A61K35/28A61M5/3129A61M5/315A61M5/32A61M2209/045A61M2202/09A61M2210/0693
Inventor 米歇尔·麦克罗根
Owner SANBIO