Preparation method of ganoderma spore composition for treating Alzheimer disease

A technology of Ganoderma lucidum spores and Ganoderma lucidum spore powder is applied in the directions of drug combinations, medical preparations containing active ingredients, pharmaceutical formulations, etc. It can solve the problems of lack of specific drugs and cure methods, and achieves swelling alleviation, simple production process and convenient operation. Effect

Inactive Publication Date: 2019-11-01
钟志强
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

At present, there are different opinions on the treatme...

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Embodiment 1

[0021] A preparation method of a ganoderma spore composition for treating senile dementia of the present invention, comprising the following steps:

[0022] S01: Harvest fresh Ganoderma lucidum spores, remove impurities and non-medicinal parts from the fresh Ganoderma lucidum spores, then wash the fresh Ganoderma lucidum spores, remove the dust on the upper part of the Ganoderma lucidum spores, and dry the fresh Ganoderma lucidum spores;

[0023] S02: Put the dried Ganoderma lucidum spores into a low-temperature supersonic airflow energy pulverizer for pulverization to form Ganoderma lucidum spore powder. The feed pressure of the low-temperature supersonic airflow energy pulverizer is 0.4-0.8mpa, and the nozzle airflow velocity is 400-450m / s , material impact temperature 20-25 ℃;

[0024] S03: Take the dried Ganoderma lucidum spore powder, pass it through a 120-mesh sieve to remove impurities, add 2-3 times the weight of pure water, stir evenly and transfer it to an ultra-high...

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Abstract

The invention belongs to the technical field of ganoderma spore compositions, and discloses a preparation method of a ganoderma spore composition for treating an Alzheimer disease. The preparation method comprises the following steps of picking fresh ganoderma spores, removing impurities and no-medicinal parts of the fresh ganoderma spores, the cleaning the fresh ganoderma spores, removing dust onthe upper parts of the ganoderma spores, and drying the fresh ganoderma spores; putting the dried ganoderma spores into a low temperature supersonic speed airflow energy grender to conduct grinding treatment, and ganoderma spore powder is formed; and taking the dried ganoderma spore powder, and through a 120 mesh screen, removing impurities. According to the ganoderma spore composition, the production technology is simple, operation is convenient, the ROS levels in blood platelets of an AD patient can be reduced by taking the ganoderma spore composition, plasma Abeta42 of the AD patient can be stabilized at a certain level, influences on the ATP levels of the blood platelets, mitochondrion COX activity of the blood platelets and the LEH level of the plasma of the AD patient are not generated, and swelling of mitochondrial of the blood platelets of the AD patient can be relaxed certainly.

Description

technical field [0001] The invention relates to the technical field of preparation of a ganoderma spore composition, in particular to a preparation method of a ganoderma spore composition for treating senile dementia. Background technique [0002] Alzheimer's disease (AD) is a progressive and age-related neurodegenerative disease, mainly manifested as cognitive impairment, memory loss, abnormal personality, and mental disorders. This disease has become one of the three major diseases that cause disability in the elderly. At present, the incidence of AD in my country over the age of 60 is 0.5% to 5.6%. Among all dementia patients, senile dementia accounts for 50%, vascular dementia accounts for 15%-20%, and mixed dementia accounts for 15%-20%. Its main pathological features are extracellular senile plaques, intracellular neurofibrillary tangles, and amyloid deposition on the vessel wall, and senile plaques are centered on Aβ deposition. The etiology and pathogenesis of seni...

Claims

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Application Information

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IPC IPC(8): A61K36/074A61P25/28
CPCA61K36/064A61K36/074A61K2236/13A61K2236/15A61K2236/17A61K2236/37A61P25/28A61K2300/00
Inventor 不公告发明人
Owner 钟志强
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