Dynamic light stimulation retinal blood oxygen saturation measurement system and measurement method thereof

Abstract

The invention discloses a dynamic light stimulation retinal blood oxygen saturation measurement system and a measurement method thereof. According to the dynamic light stimulation retinal blood oxygensaturation measurement system and the measurement method thereof, an expensive scientific research level detector does not need to be adopted, a cheap single lens reflex camera can be adopted to achieve noninvasive measurement of retinal oxygen saturation, the cost is significantly lowered, and the cost performance ratio is increased; first wavelength green light and second wavelength red light LED which are annularly and alternately arranged are skillfully adopted in a lighting source, the functional measurement upgrade of a traditional fundus camera is achieved, and the retinal blood oxygensaturation measurement system and personnel operation are also simplified; at the same time, a first wavelength green light and the second wavelength red light LED light source can emit a flashing light to stimulate the fundus of the eye dynamically, and the luminous intensity, flashing frequency and flashing mode of the first wavelength green light and the second wavelength red light LED light source all can be adjusted; the dynamic change of blood oxygen saturation of retina after light stimulation can be obtained; the influence of eye movement interference on the measurement of blood oxygen saturation is effectively avoided, and the image registration process in the subsequent calculation and processing process is also omitted.

Description

technical field [0001] The invention relates to fundus imaging technology, in particular to a dynamic light-stimulated retinal blood oxygen saturation measurement system and a measurement method thereof. Background technique [0002] As the only tissue in the whole body that can observe the rich blood vessels and their distribution in vivo under non-invasive conditions, the retinal fundus is an important window for the diagnosis of fundus lesions and related systemic diseases. At the same time, the retina has a high demand for oxygen metabolism. When the human body suffers from eye diseases or systemic diseases, the corresponding abnormal blood oxygen metabolism and dysfunction of the retina usually occur. Therefore, the non-invasive and quantitative measurement of the oxygen level in the retinal blood vessels has important scientific and clinical significance for understanding the changes of retinal oxygen metabolism in different diseases, early warning of diseases and foll...

AI Technical Summary

Problems solved by technology

[0003] However, traditional fundus imaging can only display the intuitive structural information of the fundus, but cannot detect functional information such as the oxygen content of retinal blood vessels.

At present, commercial and laboratory-developed instruments for non-invasive detection of retinal blood oxygen saturation all use scientific research-grade detectors, which are expensive and are not conducive to large-scale production and sales of instruments.

At the same time, these retinal blood oxygen saturation measuring instruments are usually modified on traditional imaging instruments such as fundus cameras, which not only need to redesign the interface for the additional scientific research-grade detectors, design synchronous triggering and acquisition control, transmission software program control and Hardware connection, and because these scientific research-grade detectors added to the original instrument are usually large in size, the center of gravity and appearance of the instrument will be greatly changed, and it will also bring a lot of inconvenience to doctors and other operators.

[0004] At the same time, the traditional detection of retinal blood oxygen saturation is aimed at static retinal blood vessels and tissues. For early detection or screening of fundus diseases or systemic diseases, static retinal blood oxygen saturation detection is usually difficult to detect Significant changes in blood oxygen saturation

Images