Application of lupinone in preparing medicine for treating kidney damage

A technology of lupine and kidney damage, which is applied in the field of application of lupine in the preparation of drugs for treating kidney damage, and can solve the problems that there is no lupine

Pending Publication Date: 2019-11-15
贵州中医药大学
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there are no reports of lupenone being used in the treatment of kidney damage

Method used

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  • Application of lupinone in preparing medicine for treating kidney damage
  • Application of lupinone in preparing medicine for treating kidney damage
  • Application of lupinone in preparing medicine for treating kidney damage

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0051] Example 1. Get lupenone (purchased from the market), add appropriate amount of conventional auxiliary materials, mix well, make granules, dry, compress into tablets, and make tablets. Each tablet contains 15mg of lupenone.

[0052] Usage and dosage: the preparation is taken twice a day, 1 to 4 tablets each time, for the treatment of kidney damage.

Embodiment 2

[0053] Example 2. Get lupine (purchased from the market), add appropriate amount of conventional auxiliary materials, mix, dry, sterilize, pack into hard capsules, pack, and make capsules. Each tablet contains 15mg of lupenone.

[0054] Usage and dosage: the preparation is taken twice a day, 1 to 4 capsules each time, for the treatment of kidney damage.

Embodiment 3

[0055] Embodiment 3: Take lupine (purchased from the market), add appropriate amount of commonly used auxiliary materials, make granules, dry, granulate, and make granules. The granule is 5g / bag, and the content of lupenone in the granule is 3mg / g.

[0056] Usage and dosage: the preparation is taken twice a day, 1 to 4 bags each time, for the treatment of kidney damage.

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PUM

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Abstract

The invention provides an application of lupinone in preparing a medicine for treating kidney damage, and provides a new idea for the development of the medicine for treating kidney damage. The invention also includes the application of lupinone for preparation of health products for treating kidney or kidney damage, the lupinone is easily available and can drive the full development and utilization of medicinal materials. Specifically, the lupinone can reduce urea nitrogen and blood creatinine in serum, the lupinone can reduce fibrous tissue proliferation and inflammatory cell infiltration, and has certain protective and repairing effects on kidney tissue damage.

Description

technical field [0001] The invention relates to the application of lupenone, a pentacyclic triterpene compound, in the preparation of medicines for treating kidney damage. Background technique [0002] The basic function of the kidney is to excrete metabolic waste in the body. Therefore, the sharp deterioration of its function will have a very serious impact on health, sometimes even fatal. Kidney damage is caused by a variety of reasons that damage the kidney function, such as the damage to the kidney structure and function caused by essential hypertension. As the course of the disease progresses, the patient will develop chronic renal insufficiency, renal failure, and eventually uremia, which seriously endangers human health. [0003] At present, the clinical methods for the treatment of kidney damage mainly include hormone therapy, dialysis therapy, and kidney replacement therapy. Drug resistance, easy recurrence and other problems. Dialysis therapy and kidney replacem...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/56A61P13/12
CPCA61K31/56A61P13/12
Inventor 吴红梅王祥培杨留波张玲玲梁玉清李小芬徐锋
Owner 贵州中医药大学
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