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New use and preparation method of traditional Chinese medicine composition

A technology of composition and traditional Chinese medicine components, applied in the field of medicine, can solve the problems of high treatment cost, striated muscle damage, toxic and side effects, etc., and achieve the effect of definite therapeutic effect, low toxic and side effects, and comprehensive effects

Inactive Publication Date: 2019-12-03
LUNAN PHARMA GROUP CORPORATION
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Statins have obvious toxic and side effects, such as hyperglycemia, striated muscle damage, liver damage and other adverse reactions, and the treatment costs are high

Method used

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  • New use and preparation method of traditional Chinese medicine composition
  • New use and preparation method of traditional Chinese medicine composition
  • New use and preparation method of traditional Chinese medicine composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0104] Embodiment 1 Mailuoshutong Granules

[0105] Prescription of Chinese medicine combination group:

[0106]

[0107] Preparation:

[0108] 1) Take honeysuckle, herb, scrophulariaceae, angelica, and white peony in a multifunctional extraction tank for steam distillation to obtain medicinal residues, medicinal liquid, and crude volatile oil; redistill the crude volatile oil to obtain refined volatile oil ;

[0109] 2) adding absolute ethanol to the refined volatile oil obtained in step 1), and mixing evenly to obtain an ethanol volatile oil solution, which is stored in an airtight container;

[0110] 3) Take the astragalus, cortex phellodendri, coix seed, licorice and 1 / 2 of the prescription amount of leech, centipede, scorpion and the dregs obtained in step 1) and decoct twice with water for 1.5 hours and 1 hour respectively. hour, combine the decoction, filter, take the medicinal solution obtained in step 1) and combine and concentrate it, add ethanol and let it sta...

Embodiment 2

[0112] Embodiment 2 Mailuoshutong tablet

[0113] Prescription of Chinese medicine combination group:

[0114]

[0115] 1) Take honeysuckle, herb, scrophulariaceae, angelica, and white peony in a multifunctional extraction tank for steam distillation to obtain medicinal residues, medicinal liquid, and crude volatile oil; redistill the crude volatile oil to obtain refined volatile oil ;

[0116] 2) adding absolute ethanol to the refined volatile oil obtained in step 1), and mixing evenly to obtain an ethanol volatile oil solution, which is stored in an airtight container;

[0117] 3) Take astragalus, Phellodendron Phellodendri, coix seed, licorice and 1 / 2 of the prescription amount of leech, centipede, scorpion and the dregs obtained in step 1) and decoct once in water for 3 hours, then filter the decoction , taking step 1) the obtained medicinal solution is combined with it and concentrated, after cooling, add ethanol and let it stand for more than 12 hours to make it ful...

Embodiment 3

[0119] Embodiment 3 Mailuoshutong dripping pills

[0120] Prescription of Chinese medicine combination group:

[0121]

[0122] 1) Take honeysuckle, atractylodes atractylodes, Radix Scrophulariae, Radix Scrophulariae Scrophulariae, Radix Scrophulariae Scrophulariae, and Radix Paeoniae Alba in a multifunctional extraction tank for steam distillation to obtain medicinal residues, medicinal liquid, and crude volatile oil; redistill the crude volatile oil to obtain refined volatile oil;

[0123] 2) adding absolute ethanol to the refined volatile oil obtained in step 1), and mixing evenly to obtain an ethanol volatile oil solution, which is stored in an airtight container;

[0124] 3) Take astragalus, cortex phellodendri, coix seed, licorice and 1 / 2 prescription amount of leech, centipede, scorpion and the dregs obtained in step 1) and decoct twice with water for 1.5 hours and 1 hour respectively. Combine the decoctions, filter, take the medicinal solution obtained in step 1) a...

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Abstract

The present invention discloses an application of a traditional Chinese medicine composition made of radix astragali, honeysuckle, cortex phellodendri, rhizoma atractylodis, radix scrophulariae, Chinese angelica, radix paeoniae alba and coix seeds in preparation of drugs for treating carotid atherosclerosis with vulnerable plaque and belongs to the field of medicine. The composition reduces carotid intima-media thickness (IMT) by reducing total serum cholesterol, triglyceride, low-density lipoprotein and serum inflammation index Hs-CRP of patients, can stabilize the carotid atherosclerosis with the vulnerable plaque, and thus effectively reduces occurrence of acute cardiovascular and cerebrovascular events caused by the carotid atherosclerosis with the vulnerable plaque. The traditional Chinese medicine composition is low in toxic and side effects when used for treating the carotid atherosclerosis with the vulnerable plaque, has a precise therapeutic effect and has broad market prospects.

Description

technical field [0001] The invention relates to a new application of a traditional Chinese medicine composition and a preparation method thereof, in particular to an application of a traditional Chinese medicine composition in the preparation of medicines for treating carotid atherosclerosis with vulnerable plaques and a preparation method thereof, belonging to the field of medicine. Background technique [0002] With the continuous improvement of people's living standards, many adverse changes in eating habits and living habits, coupled with increased work pressure and environmental pollution in the fast-paced life, more and more patients suffer from cardiovascular and cerebrovascular diseases, among which stroke is the most common One of the most prevalent and harmful diseases. The disease often has an acute onset, and functional impairments such as language, limbs, and consciousness appear rapidly, and severe cases are life-threatening. [0003] As an important blood ves...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8994A61P9/10A61K35/648A61K35/646A61K35/62
CPCA61K36/481A61K36/355A61K36/756A61K36/284A61K36/808A61K36/232A61K36/71A61K36/65A61K36/8994A61K35/648A61K35/646A61K35/62A61K36/484A61P9/10A61K2236/331A61K2236/333A61K2236/39A61K2300/00
Inventor 张贵民李蔚群王永刚
Owner LUNAN PHARMA GROUP CORPORATION
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