Preparation process of carboxymethyl chitosan hemostatic sponge

Abstract

The invention discloses a preparation process of carboxymethyl chitosan hemostatic sponge and relates to the technical field of preparation of carboxymethyl chitosan hemostatic sponge. The carboxymethyl chitosan hemostatic sponge comprises components as follows: 1-10 parts of carboxymethyl chitosan, 1-10 parts of chitosan oligosaccharide, 1-10 parts of beta-chitosan, 1-10 parts of carboxymethyl chitosan fiber, 1-10 parts of collagen and 1-5 parts of glycerin, wherein the collagen is fish collagen. The carboxymethyl chitosan hemostatic sponge prepared by the preparation process has good biocompatibility, expands quickly after absorbing water, permeates quickly, has very high water absorption ratio, allows good gas exchange, has good liquid absorption performance, keeps wet healing environment for wounds and can isolate outer layer structures and prevent invasion of microorganisms so as to create an ideal healing environment for wounds.

Description

technical field [0001] The invention relates to the technical field of preparation of carboxymethyl chitosan hemostatic sponge, in particular to a preparation process of carboxymethyl chitosan hemostatic sponge. Background technique [0002] Chitosan is rich in resources. As the second largest natural polysaccharide, chitin is widely found in crab shells, shrimp shells and arthropod shells, and also in the cell walls of lower plants such as bacteria and algae. It is biosynthesized every year in nature. There are billions of tons of chitin. [0003] Chitosan and its derivatives have many advantages such as non-toxic, biodegradable, good biocompatibility, adsorption, adhesion, reactivity, safety and antibacterial properties, and chitosan also has good fiber-forming properties. properties, which again expands the scope of application of chitosan. [0004] With the continuous development of modern medical technology, more and more new technologies have been developed and used....

AI Technical Summary

Problems solved by technology

[0004] With the continuous development of modern medical technology, more and more new technologies have been developed and used. In view of the fibrous properties of chitosan, it can be applied to medicine. The existing hemostatic materials are not effective and have poor biocompatibility. Some cost is also higher, for this reason, we have proposed a kind of preparation technology of carboxymethyl chitosan hemostatic sponge