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Traditional Chinese medicine composition containing rodgersia aesculifolia batal and preparation method thereof

The technology of the old snake lotus and the composition is applied in the field of traditional Chinese medicine compositions containing the old snake lotus and its preparation, which can solve the problems of difficulty in preparing granules, many impurity components, etc., so as to improve the bioavailability, improve the curative effect, overcome the low bioavailability

Pending Publication Date: 2020-01-03
广西万寿堂药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the original preparation process of Jinlian Weishu Tablets, the medicinal flavor of the old snake lotus in the other party was not extracted, and it was directly crushed and used as medicine. There were many impurities, so it was difficult to apply to the preparation of granules.

Method used

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  • Traditional Chinese medicine composition containing rodgersia aesculifolia batal and preparation method thereof
  • Traditional Chinese medicine composition containing rodgersia aesculifolia batal and preparation method thereof
  • Traditional Chinese medicine composition containing rodgersia aesculifolia batal and preparation method thereof

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0045] R1. Get 147 parts of alum (calcined), 4 parts of Jinbuhuan total alkali, and 143 parts of old snake lotus;

[0046] R2. Take the old snake lotus, crush it into a coarse powder, add 50% ethanol solution for reflux extraction 3 times, add 15 times the amount of 50% ethanol solution for reflux extraction for 1 hour for the first time, add 12 times the amount of 50% ethanol solution for reflux for the first time Extract for 1 hour, add 8 times the amount of 50% ethanol solution for the first time to reflux for extraction for 1 hour, filter, combine the filtrates, concentrate to a thick paste, dry, and pulverize to obtain a dry paste fine powder;

[0047] R3. get alum (calcined) and pulverize into fine powder;

[0048] R4. Take the dry paste fine powder of step R2, the fine powder of R3 and the total alkali fine powder of Jinbuhuan, and mix well to obtain a mixed medicinal powder;

[0049] R5. above-mentioned mixed powder is pressed mixed powder: starch: sodium carboxymethy...

Embodiment 2

[0051] R1. Get 147 parts of alum (calcined), 4 parts of Jinbuhuan total alkali, and 143 parts of old snake lotus;

[0052] R2. Take the old snake lotus, crush it into a coarse powder, add 50% ethanol solution for reflux extraction twice, add 12 times the amount of 50% ethanol solution for reflux extraction for 2 hours for the first time, add 8 times the amount of 50% ethanol solution for reflux for the first time Extract for 2 hours, filter, combine the filtrates, concentrate to a thick paste, dry, pulverize to obtain a dry paste fine powder;

[0053] R3. get alum (calcined) and pulverize into fine powder;

[0054] R4. Take the dry paste fine powder of step R2, the fine powder of R3 and the total alkali fine powder of Jinbuhuan, and mix well to obtain a mixed medicinal powder;

[0055] R5. above-mentioned mixed powder is pressed mixed powder: starch: sodium carboxymethyl starch: the ratio of stevia=9.2:5:4:0.2 adds starch, sodium carboxymethyl starch and steviol, mixes, and 7...

Embodiment 3

[0057] R1. Get 147 parts of alum (calcined), 4 parts of Jinbuhuan total alkali, and 143 parts of old snake lotus;

[0058] R2. Take the old snake lotus, crush it into a coarse powder, add 50% ethanol solution for reflux extraction twice, add 13 times the amount of 50% ethanol solution for reflux extraction for 2 hours for the first time, add 10 times the amount of 50% ethanol solution for reflux for the first time Extract for 1 hour, filter, combine the filtrates, concentrate to a thick paste, dry, pulverize to obtain a dry paste fine powder;

[0059] R3. get alum (calcined) and pulverize into fine powder;

[0060] R4. Take the dry paste fine powder of step R2, the fine powder of R3 and the total alkali fine powder of Jinbuhuan, and mix well to obtain a mixed medicinal powder;

[0061]R5. above-mentioned mixed powder is pressed mixed powder: starch: sodium carboxymethyl starch: the ratio of stevia=9.2:5:4:0.2 adds starch, sodium carboxymethyl starch and steviol, mixes, and 70...

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Abstract

The invention discloses a traditional Chinese medicine composition containing rodgersia aesculifolia batal and a preparation method thereof. The traditional Chinese medicine composition is mainly prepared from the following raw material components in parts by weight: 147 parts of alum (calcine), 4 parts of kempas total alkali and 143 parts of the rodgersia aesculifolia batal. The products producedby the preparation method meet the needs of people for the diversification of preparations in daily life, the bioavailability of the products is further improved, the defects of the low bioavailability of original tablets are overcome, and the efficacy of the products is improved. The results of clinical trials show that the traditional Chinese medicine composition has a good effect in the treatment of chronic gastritis and peptic ulcer, and is safe and reliable to take, and does not have adverse reactions and side effects.

Description

technical field [0001] The invention relates to the field of medicines, in particular to a traditional Chinese medicine composition containing snake lotus and a preparation method thereof. Background technique [0002] Traditional Chinese medicine granules are developed on the basis of traditional Chinese medicine decoctions. They not only have the characteristics of easy absorption and quick effect of traditional decoctions, but also avoid decoction before taking, and have a longer shelf life and are easy to carry. Tablet injection is relatively simple, but its bioavailability is significantly better than that of tablet, so it has a good market prospect. [0003] Jinlian Weishu tablet is recorded in WS-10762(ZD-0762)-2002. It is prepared from alum, total alkaloids of Jinbuhuan and three traditional Chinese medicines of Laoshelian and auxiliary materials. Peptic ulcer is seen in stomach pain and acid regurgitation caused by liver-stomach disharmony and stomach-heat syndrome...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/59A61K9/16A61P1/04A61P29/00A61K33/06
CPCA61K9/1652A61K33/06A61K36/42A61K36/59A61K2236/333A61K2236/39A61P1/04A61P29/00A61K2300/00
Inventor 李修善施少莉刘雄
Owner 广西万寿堂药业有限公司
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