A one-step double-layer micro-droplet generation device and method
A micro-droplet and droplet technology, applied in chemical instruments and methods, laboratory utensils, laboratory containers, etc., can solve problems such as the complexity of the flow channel production process, simplify the production process, shorten the production cycle, and improve the structure simple effect
Active Publication Date: 2021-04-16
HUAZHONG UNIV OF SCI & TECH
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Problems solved by technology
[0004] The technical problem to be solved by the present invention is to provide an optimized double-layer micro-droplet generating device to shorten the production time of the microfluidic chip in view of the defect that the flow channel manufacturing process in the double-layer micro-droplet structure is relatively complicated in the prior art. Process, easy to manufacture, improve efficiency
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[0036] In order to make the object, technical solution and advantages of the present invention clearer, the present invention will be further described in detail below in conjunction with the accompanying drawings and embodiments. It should be understood that the specific embodiments described here are only used to explain the present invention, not to limit the present invention.
[0037] Such as figure 1 As shown, the present invention provides a one-step double-layer micro-droplet generating device, including a microfluid injection module 1, a microfluidic chip 2, and a droplet collection module 3. The outlet of the fluid injection module 1 is connected to the droplet collection module 3 through a capillary 4 . The microfluidic chip 2 has an axisymmetric structure, and the outer phase inlet 21, the middle phase inlet 22, the inner phase inlet 23, the flow focusing module 24 and the droplet outlet 25 are respectively arranged on the symmetrical axis, and only one flow focus...
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The invention discloses a one-step multi-layer micro-droplet generating device, which comprises a microfluid injection module, a microfluidic chip and a droplet collection module. The droplet collection module; the microfluidic chip has an axisymmetric structure, and the external phase inlet, the middle phase inlet, the internal phase inlet, the flow focusing module and the droplet outlet are respectively arranged on the symmetrical axis. Connected structure, the external phase inlet is connected to port A and port E of the flow focusing module through a three-way module through a microchannel, and the middle phase inlet is connected to port B and port E of the flow focusing module through a three-way module through a microchannel. Port D, the internal phase inlet is connected to port C of the flow focusing module through a microchannel, and port F of the flow focusing module is connected to the droplet outlet. The invention has a simple structure, simplifies the manufacturing process of the microfluidic chip, shortens the manufacturing cycle and improves the production efficiency.
Description
technical field [0001] The invention relates to microfluidic technology generation technology, in particular to a method for generating double-layer micro-droplets based on a flow focusing module. Background technique [0002] In the double-layer micro-droplet structure, the intermediate phase fluid wraps the inner phase fluid and exists stably in the outer phase fluid. By solidifying the mesophase fluid, bilayer microdroplets can be made into capsule-like structures. The properties of the interphase fluid are adjusted so that the capsule-like structure can be broken under specific circumstances, and the internal phase fluid is released at a specific time or place to take effect. Therefore, double-layer microdroplets play an important role in food, chemical industry, medicine, agriculture, etc. [0003] The generation of bilayer microdroplets using the flow focusing module is mainly divided into one-step generation and two-step generation. The disadvantage of the two-step...
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Login to View More IPC IPC(8): B01L3/00
CPCB01L3/0241B01L3/5027B01L2200/027B01L2300/0838B01L2300/12B01L2300/165
Inventor 肖峻峰吴佳理陈肖牛牧原罗优明刘祥王强郭枫许剑锋
Owner HUAZHONG UNIV OF SCI & TECH