Experimental method of autogenous adipose stem cell and PRP in treatment of osteoarthritis

Abstract

The invention discloses an autologous adipose stem cell, and specifically relates to an autologous adipose stem cell experimental method of PRP for treating osteoarthritis. The method includes the following steps: selecting the components of autologous stem cells as the patient's autologous adipose stem cells and high-concentration platelet plasma, isolating and culturing the adipose stem cells for 2 to 4 weeks, obtaining cultured adipose stem cells, adding the high-concentration platelet plasma into the adipose stem cells to obtain a mixture of adipose stem cells, adding growth factors and conversion factors, uniformly mixing, filtering, removing filter residue, taking a clear filtrate as an injection, and selecting injection points at joints where the patient suffers from osteoarthritisfor injection. The adipose stem cell mixture can effectively reduce the inflammatory response of osteoarthritis and the patient's own immune response, and has a significant effect on the treatment ofosteoarthritis.

Description

technical field [0001] The invention relates to the field of application of autologous fat stem cells, in particular to an experimental method for treating osteoarthritis with autologous fat stem cells+PRP. Background technique [0002] Osteoarthritis (OA) is a common degenerative disease in the elderly, with typical clinical manifestations of joint pain and limited mobility. With an aging population and changing lifestyles worldwide, musculoskeletal disorders are the most common cause of long-term chronic pain and disability affecting tens of millions of people worldwide. Therefore, seeking to innovate a safe, effective, large-source, and non-ethical-controversial cell transplantation treatment method can bring great benefits to osteoarthritis patients, and can also greatly meet the current market demand and have great potential. industrialization prospects. [0003] Osteoarthritis (OA), also known as degenerative arthritis or osteoarthrosis, is a joint disease that poten...

AI Technical Summary

Problems solved by technology

[0006] The purpose of the present invention is to provide an experimental method for treating osteoarthritis with autologous fat stem cells+PRP, to solve the long-term chronic pain and disability caused by the existing treatment of osteoarthritis, and to better prevent infection. PRP can be coagulated into a gel with thrombin, which can not only bind tissue defects, but also prevent the loss of platelets, so that platelets can secrete growth factors locally for a long time, maintain a high concentration of growth factors, and avoid clinical liquid recombinant growth factor reagents Disadvantages of easily draining and evaporating in wounds

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