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Method and device for debugging laser beam expander of sequencer

A debugging method and beam expander technology, applied in the direction of biochemical instruments, biochemical cleaning devices, biochemical equipment and methods, etc., can solve the problems of low precision, large strength damage, etc., and achieve the effect of high precision and high efficiency

Pending Publication Date: 2020-04-28
WUHAN BGI CLINICAL LAB CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] However, in the existing technology, the uniformity of the laser can only be checked by the naked eye, and then adjusted. The adjustment accuracy of this method is low, and repeated adjustments are required to achieve a general effect, and the long-term visual inspection of the laser will cause great damage to the strength.

Method used

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  • Method and device for debugging laser beam expander of sequencer
  • Method and device for debugging laser beam expander of sequencer
  • Method and device for debugging laser beam expander of sequencer

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Embodiment 1

[0043] This embodiment provides a debugging device for a laser beam expander of a sequencer. The debugging device is used to measure the uniformity of the laser instead of the naked eye, and calculate the angle value to be adjusted, so as to realize accurate and efficient adjustment.

[0044] Such as figure 1 and figure 2 As shown, the debugging device of this embodiment mainly includes a laser power sensor 1 , a processor 2 and a display 3 .

[0045] There are several laser power sensors 1 , and eight are taken as an example for illustration in this embodiment. Eight laser power sensors 1 are arranged on the optical path of laser beam emitted by the laser beam expander 4 of the sequencer, and the eight laser power sensors 1 are arranged on a straight line at equal intervals, and the straight line where the eight laser power sensors 1 are located is aligned with the optical axis of the laser vertical, so that the eight laser power sensors 1 can simultaneously detect the lig...

Embodiment 2

[0056] This embodiment provides a debugging device for a laser beam expander of a sequencer. The debugging device mainly includes a light intensity value detection device. The light intensity value detection device is a detection device in the prior art. For example, the light intensity value detection device is a photometric instrument.

[0057] The light intensity value detection device includes a detection module, a processing module and a display module, and the processing module is connected to the detection module and the display module with signals respectively.

[0058] The detection module is an optical sensor, which is used to move to several positions on the same focal plane where the laser beam expander emits laser light, so as to obtain illumination at different positions on the same focal plane of the laser, generate corresponding laser light intensity signals, and The signal is sent to the processing module.

[0059] The processing module can calculate the lase...

Embodiment 3

[0064] This embodiment provides a debugging method for a laser beam expander of a sequencer, which is implemented based on the debugging device in the first embodiment above.

[0065] like Figure 6 As shown, the debugging method of this embodiment includes the following steps:

[0066] S01: Detect the laser light intensity value;

[0067] The laser beam expander 4 of the sequencer emits expanded laser light, and the laser light is respectively irradiated on eight laser power sensors 1 arranged vertically to the optical axis.

[0068] The eight laser power sensors 1 obtain laser irradiation respectively, generate corresponding laser light intensity signals, and transmit the light intensity signals to the processor 2 .

[0069] In order to calculate the adjustment angle value more accurately, the laser beam expander 4 of the sequencer irradiates multiple times, and the laser power sensor 1 will generate multiple laser light intensity signals. Each irradiation will generate 8 ...

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Abstract

The invention discloses a method and device for debugging a laser beam expander of a sequencer. The debugging method comprises the following steps: detecting the laser intensity values of a pluralityof positions on the same focal plane of laser emitted by the laser beam expander; calculating the deviation coefficient of the beam expander according to the laser intensity values of the plurality ofpositions, and calculating an adjustment angle value; and adjusting an adjusting knob on the laser beam expander according to the calculated adjustment angle value, and carrying out focusing debugging. The light intensities of the emitted laser at different positions on the same focal plane are detected to be small, the uniformity of the laser intensities is calculated and analyzed, the adjustment angle value is calculated, and debugging personnel can conduct focusing adjustment on the laser beam expander of the sequencer according to the calculated adjustment angle value to realize uniformity debugging of the laser beam expander of the sequencer. The debugging method and device are completed with the help of equipment, and the debugging precision and efficiency are high.

Description

technical field [0001] The invention relates to optical equipment for gene sequencing, in particular to a debugging method and device for a laser beam expander of a sequencer. Background technique [0002] In the process of gene sequencing, the sequencing light is generated by the laser, which emits divergent light as a point light source, and the space that the gene sequencing chip needs to scan is a line segment, so it is necessary to convert the point light source into a line light source. [0003] At present, the adjustable sequencer laser beam expander is used as the light source of the sequencer. The laser beam expander includes a laser (point light source) and a beam expander. The beam expander includes a fixed lens and a moving lens on the optical path of the laser emitted light. , the outside of the laser beam expander is provided with an adjustment knob, which is connected to the moving lens and used to adjust the distance between the moving lens and the fixed lens...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12Q1/6869C12M1/34
CPCC12Q1/6869
Inventor 刘晨黄金田志坚许振朋周晏秋卢安值
Owner WUHAN BGI CLINICAL LAB CO LTD