Method for calculating contrast blood flow reserve fraction and resting pressure ratio based on contrast images

Abstract

The invention discloses a method for calculating contrast blood flow reserve fraction based on contrast images. The method comprises the following steps: measuring pressure Pa of a coronary artery port of a heart through a blood pressure sensor; acquiring two-dimensional pipe diameter and length of a blood vessel through the contrast images, generating a three-dimensional blood vessel grid model through two contrast images with included angles of 30 degrees or more, and acquiring the three-dimensional pipe diameter and length of the blood vessel; measuring time taken by blood containing contrast agents moving from a starting point to an ending point of a specified blood vessel, and calculating blood flow velocity V<1> according to the time and the three-dimensional length of the blood vessel; and taking the blood flow velocity V<1> as a coronary artery inlet flow velocity to calculate pressure drop delta P<1> from a coronary artery inlet to a coronary artery stenosis distal end, calculating average pressure P<d1> in the coronary artery stenosis distal end through a formula of P<d1>=Pa-delta P<1>, and calculating the contrast blood flow reserve fraction through a formula of cFFR=P<d1> / Pa. Therefore, cFFR and resuming Pd / Pa can be obtained by conventional contrast images without use of vasodilators.

Description

technical field [0001] The present invention relates to the field of coronary imaging evaluation, in particular to a method for calculating contrast fractional flow reserve (cFFR) and resting pressure ratio (resting Pd / Pa) based on contrast images. Background technique [0002] Fractional flow reserve (FFR) can indicate the influence of coronary artery stenosis on distal blood flow, and it has become a recognized index for functional evaluation of coronary artery stenosis in diagnosing myocardial ischemia. FFR is defined as the ratio of the maximum blood flow supplied to the myocardium by a narrowed coronary artery to the maximum blood flow supplied to the myocardium by the same coronary artery when it is normal. It can be simplified as the ratio of the mean pressure (Pd) in the coronary artery at the distal end of the stenosis to the mean pressure (Pa) in the aorta at the coronary ostium under the state of maximum myocardial hyperemia, that is, FFR=Pd / Pa. [0003] When det...

AI Technical Summary

Problems solved by technology

It needs to rely on the pressure guide wire for measurement. The pressure guide wire needs to intervene at the end of the blood vessel, which increases the difficulty and risk of the operation. At the same time, the expensive price of the pressure guide wire also limits its large-scale application

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