Disinfectant for killing envelope-type viruses and preparation method of disinfectant

A disinfectant and virus technology, applied in the directions of disinfectants, antiviral agents, botanical equipment and methods, etc., can solve the problems of difficulty in large-scale promotion, health effects, complex components, etc., achieve no skin allergy, improve Good adhesion and biocompatibility

Inactive Publication Date: 2020-05-19
GUANGXI FORESTRY RES INST
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, this disinfectant is mainly based on chemical raw materials, which will have a certain impact on the health of animals or human bodies, and the components are very complicated, and the cost is high, so it is difficult to achieve large-scale promotion

Method used

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  • Disinfectant for killing envelope-type viruses and preparation method of disinfectant
  • Disinfectant for killing envelope-type viruses and preparation method of disinfectant
  • Disinfectant for killing envelope-type viruses and preparation method of disinfectant

Examples

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Effect test

Embodiment 1

[0019] A disinfectant for killing enveloped viruses, which is composed of the following raw materials in mass percentage: 5% refined bamboo vinegar, 5% tea saponin, and the balance is water; the preparation method of the refined bamboo vinegar is as follows: the bamboo vinegar Add 100 parts of the stock solution into the reaction kettle, add 10 parts of calcium carbonate and mix evenly under stirring, then adjust the pH value to 6 with alkali, filter the supernatant, add 10 parts of activated carbon, stir for 10 minutes, filter, and pump out the mixture in a fractionation tower at 60 ° C. Vacuum fractional distillation, respectively collected fractions, to obtain refined bamboo vinegar.

[0020] Table 1: Comparison of physical and chemical properties between refined bamboo vinegar of the present invention and bamboo vinegar stock solution

[0021]

[0022]

[0023] Measure the synergistic effect of the disinfectant of this embodiment according to conventional methods, an...

Embodiment 2

[0051]A disinfectant for killing enveloped viruses, which is composed of the following raw materials in mass percentage: 3% refined bamboo vinegar, 5% tea saponin, and the balance is water; the preparation method of the refined bamboo vinegar is as follows: the bamboo vinegar Add 100 parts of the stock solution into the reaction kettle, add 5 parts of calcium carbonate and mix evenly under stirring, then adjust the pH value to 5 with alkali, take the supernatant by filtration, add 10 parts of activated carbon, stir for 5 minutes, filter, and extract from the fractionation tower at 70°C Vacuum fractional distillation and fractions were collected separately to obtain refined bamboo vinegar.

Embodiment 3

[0053] A disinfectant for killing enveloped viruses, which is composed of the following raw materials in mass percentage: 4% refined bamboo vinegar, 3% tea saponin, and the balance is water; the preparation method of the refined bamboo vinegar is as follows: the bamboo vinegar Add 100 parts of stock solution into the reaction kettle, add 10 parts of calcium carbonate under stirring and mix evenly, then adjust the pH value to 4 with alkali, take the supernatant by filtration, add 8 parts of activated carbon, stir for 5 minutes, filter, and extract from the fractionation tower at 65°C Vacuum fractional distillation and fractions were collected separately to obtain refined bamboo vinegar.

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Abstract

The present invention discloses a disinfectant for killing envelope-type viruses and a preparation method of the disinfectant. The disinfectant comprises the following raw materials in mass percentages: 3-6% of refined bamboo vinegar, 3-5% of tea saponin and the balance water; and the refined bamboo vinegar is prepared by the following steps; adding 100 parts of a bamboo vinegar stock solution into a reaction kettle, adding 5-10 parts of calcium carbonate for even mixing under stirring, then adjusting pH value to 3-6 with alkali, conducting filtering, taking a supernatant, adding 5-10 parts ofactivated carbon, conducting stirring for 5-10 minutes, conducting filtering, conducting fractionation under reduced pressure, and collecting a fraction of the refined bamboo vinegar. The provided refined bamboo vinegar is mainly prepared from organic acids, has a killing effect on the envelope-type viruses, then is combined with a natural nonionic surfactant of the tea saponin, significantly improves penetration of a medicine solution by destroying a structure of envelopes, improves adhesion of the medicine solution on surfaces of the viruses, and plays a synergistic effect. The prepared disinfectant has good biocompatibility, is also free of acute toxicity, irritation to the skin and skin allergic reaction, is safe for human body and animals, and prevents spreads of avian influenza viruses, swine flu and other envelope-type viruses.

Description

technical field [0001] The invention belongs to the technical field of disinfectants, in particular to a disinfectant for killing enveloped viruses and a preparation method thereof. Background technique [0002] In recent years, highly pathogenic avian influenza has not only caused huge economic losses to my country's poultry breeding industry, but also posed a serious threat to public health security. Avian influenza virus (AIV) is a type A influenza virus. Influenza viruses belong to the Orthomyxoviridae family of RNA viruses and are divided into three types: A, B, and C. Among them, influenza A virus is mostly found in poultry. Influenza A virus is pleomorphic, with a spherical diameter of 80-120nm and a capsule. The genome is segmented single-stranded negative-sense RNA. According to the antigenicity of the outer membrane hemagglutinin (H) / neuraminidase (N) protein, it can be divided into 16 H subtypes (H1~H16) and 9 N subtypes (N1~N9). The subtypes of avian influen...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61P17/00A61P31/16A61P31/02A01N61/00A01N43/16A01N65/08A01N65/30A01N65/22A01P1/00A61K31/704
CPCA01N43/16A01N61/00A01N65/00A01N65/08A01N65/22A01N65/30A61K31/704A61K36/195A61K36/258A61K36/315A61K36/534A61K36/65A61K36/704A61K36/71A61K36/855A61K36/899A61K2236/331A61P17/00A61P31/02A61P31/16A61K2300/00
Inventor 杨漓马锦林谷瑶周丽珠李桂珍
Owner GUANGXI FORESTRY RES INST
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