Method and device for predicting dose volume histogram of organ-at-risk of radiotherapy plan
A prediction method and histogram technology, applied in the field of medical radiation therapy, can solve the problems of not covering the characteristics of the patient's anatomical structure, reducing the accuracy and scope of clinical application, etc.
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Embodiment 1
[0076] Embodiment 1 of the present invention provides a method for predicting the dose volume histogram (Dose Volume Histogram, DVH) of organs at risk in radiotherapy planning, and the specific flow chart is as follows figure 1 As shown, the specific process is as follows:
[0077] Step 1: Based on the CT images in the expert radiotherapy planning medical image database and the anatomical structure map and dose distribution map of the region of interest (body contour-target region-organ-at-risk), determine the anatomical structure map and sensory diagram of the region of interest used for model training. Dose Area Histogram (DAH) for organs at risk of interest;
[0078] In step 1, a medical image database of expert radiotherapy plans is established. The basis for selection is that the radiotherapy plan data is complete and the anatomical structure of the region of interest is clearly outlined. Senior physicists and radiotherapy doctors will confirm together to ensure the sel...
Embodiment 2
[0132] Based on the same inventive concept, Embodiment 2 of the present invention also provides a device for predicting the dose volume histogram of organs at risk in radiotherapy planning, such as figure 2 As shown, the functions of each component are described in detail below:
[0133] The determination module is used to determine the anatomical structure diagram of the region of interest and the dose area histogram of the organ at risk of interest for model training based on the CT image in the expert radiotherapy planning medical image database and the anatomical structure diagram and dose distribution diagram of the region of interest ;
[0134] The modeling module is used to input the anatomical structure map of the region of interest used for model training and the dose area histogram of the organ at risk of interest into the deep learning network for training to obtain a prediction model;
[0135] The prediction module is used to determine the anatomical structure ma...
Embodiment 3
[0183] Embodiment 3 of the present invention takes nasopharyngeal carcinoma as an example to introduce the method of predicting the dose-volume histogram of organs at risk in the radiotherapy plan, and completes the DVH prediction of new patients to realize the process of automatically setting the initial objective function of the reverse plan and the plan quality inspection, specifically including the following steps :
[0184] (T1) Establish an expert database for radiotherapy planning for nasopharyngeal carcinoma, including the following:
[0185] (T1.1) Collect the radiotherapy planning data of 190 TOMO nasopharyngeal carcinoma patients admitted to the Cancer Hospital of the Chinese Academy of Medical Sciences from 2014 to 2017, among which 136 cases were randomly selected as the training data set, 34 cases were used as the verification data set, and 20 cases were used as the test data set;
[0186] (T1.2) For each radiotherapy plan, it includes CT images, anatomical stru...
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