Fluorescence radiography examination system based on 785nm-wavelength light source

Abstract

The invention belongs to the technical field of near-infrared fluorescence imaging and in particular relates to a fluorescence radiography examination system based on a 785nm-wavelength light source.The system comprises a near-infrared laser light-emitting source, a visible light illumination light source, a light collector, a light splitter, a visible light filter, a near-infrared light filter,a color camera, a near-infrared camera, a terminal display and a shell used for making contact with body tissue of a patient. A light source bracket is arranged in the shell; the near-infrared laser light-emitting source and the visible light illumination light source are arranged on the light source bracket, an observation channel is arranged in the shell and connected with the light collector, the light splitter is connected with the light collector, the color camera is connected with the light splitter through the visible light filter, and the near-infrared camera is connected with the light splitter through the near-infrared light filter. The designed fluorescence radiography examination system can block useless exciting light reflected back to fluorescence detection equipment from thesurface of body tissue, the influence of a large amount of reflected exciting light on a picture is avoided, the signal-to-noise ratio of the image is increased, and the image effect is enhanced.

Description

technical field [0001] The invention relates to the technical field of near-infrared fluorescence imaging, in particular to a fluorescence contrast inspection system based on a 785nm wavelength light source. Background technique [0002] Labeling biomolecules with radiotracers and fluorescent dyes has been used successfully in biomedical research for several years, but in the field of actual in vivo clinical medical imaging, the use of fluorescent probes in clinical research has been mostly limited to Examination of in vitro stained tissue sections. Until the late 1980s, some researchers attempted to inject exogenous fluorescent dyes into living organisms as contrast agents to distinguish diseased and normal tissues in tumor detection through non-invasive or endoscopic optical measurement methods. In recent years, great achievements have been made in the use of fluorescent indicators as exogenous contrast agents in in vivo imaging of tumors using near-infrared. [0003] In...

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Problems solved by technology

[0004] However, in the prior art, only the area image of blood containing fluorescent contrast agent can be observed and displayed, but the image of the unexcited part of blood without fluorescent contrast agent cannot be displayed

In this way, the operator can only see the lymphatic body at the irradiated site but not the whole surgical area including the lymphatic body. If you want to see the overall situation of the entire surgical area, you need to turn off the irradiated laser light source, but in this way Then the position and shape of the desired resection site cannot be seen. For this reason, the operator needs to repeatedly switch between irradiating near-infrared light and turning off near-infrared light. The application is very inconvenient and causes trouble during the operation. Therefore, we propose A fluoroscopy inspection system based on a 785nm wavelength light source is used to solve the above problems

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