Testing device for in-group levels of small animals and experimental method

A technology of testing device and experimental method, applied in application, other equipment, animal husbandry, etc., to achieve the effects of easy cleaning, high efficiency, and improved reliability

Inactive Publication Date: 2020-09-04
NINGBO UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, so far, there is no related experimental setup ...

Method used

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  • Testing device for in-group levels of small animals and experimental method
  • Testing device for in-group levels of small animals and experimental method
  • Testing device for in-group levels of small animals and experimental method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] The experimental method using the above-mentioned small animal group test device is as follows:

[0034] Step 1: Purchase 21-day-old SD rats (SD rat weaning age) from an experimental animal company with a production and sales license for experimental animals, pair them randomly with 4 cages, mark each animal, weigh and weigh Records: After the animals were purchased, they were raised in a constant temperature and humidity environment where day and night were reversed to ensure sufficient supply of feed and drinking water until they were 70 days old (the adult age of SD rats).

[0035]Step 2: Take and record the body weight of every rat in every cage at the age of 70 days, and then use 24g of feed per cage of rats every day (that is, 6g per rat every day, adult rats need about 12g of feed every day to maintain body weight) ) were fed, and the body weight of each rat in each cage was weighed every day until the body weight of all rats dropped to 80% to 90% of the body wei...

Embodiment 2

[0041] The basic steps are the same as in Example 1, but on the second day after testing the animal's social rank for the first time (step 5 ends), give the animal an acute exposure to a certain drug, and then carry out a social rank test (i.e. repeat step 5), Observing and judging the effect of acute effects of a drug on adult animals on their social class.

Embodiment 3

[0043] The basic steps are the same as in Example 1, but after the first test of the animal's social class (end of step 5), the animal is acutely exposed to a certain drug for several days, and the social class is performed again after the last acute effect of the drug exposure is over. Test (ie, repeat step 5) to observe and judge the effect of chronic effects of a drug on adult animals on their social class.

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Abstract

A testing device for in-group levels of small animals comprises a waiting bin, a channel pipe, a food box, an infrared camera and a video recording computer, wherein a slot is formed in the waiting bin, a slot door is arranged in the slot in an inserted manner, animal feed is placed in the food box, an openable cover is arranged at the top of the food box, the waiting bin and the food box are connected through the channel pipe, and the infrared camera and the video recording computer are electrically connected through a data transmission line. Fighting of animals for limited food is strengthened through movement limitation and hunger treatment of animals, and the fighting for food is converted into competition of food space. The competition of the animals for the food and food space induces the animals to show the real social status in groups. The invention also provides an experimental method using the device. Compared with a traditional device, the testing device is proved to have more stable and reliable experimental results, can substantially enhance the experimental efficiency, and also has the advantages that experimental operation is simple and easy to master, and the experimental device is convenient to mount and dismount and occupies no space and the like.

Description

technical field [0001] The invention relates to the field of biological experiment devices, in particular to a level test device within a group of small animals and an experimental method using the device. Background technique [0002] As social animals, humans and rodents have their social and social attributes, and social hierarchy is a concentrated expression of the comprehensive interaction of social attributes of animals, including social interaction, material competition and distribution. Research on the social hierarchy of social animals can help people better understand and explain the comprehensive and complex social relationships of social animals, and the impact of humanities, history, environment, drugs, neural mechanisms, etc. on the formation of social hierarchy of social animals and role. [0003] At present, the social level tests of small animals mainly include the pipeline experiment and the hot spot experiment. The pipeline experiment is based on the anim...

Claims

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Application Information

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IPC IPC(8): A01K29/00
CPCA01K29/005
Inventor 余志鹏
Owner NINGBO UNIV
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