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A disinfectant and wound technology, applied in the field of disinfectant, to achieve good permeability and hydration floating effect, good biocompatibility, and the effect of promoting wound healing
Inactive Publication Date: 2020-09-11
HUAREN PHARMACEUTICAL CO LTD +3
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However, the wound disinfectant currently on the market only has basic debridement or disinfection effects, and does not have other effects. For
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[0017] The present invention also provides a specific embodiment of the preparation method of the above-mentioned wound disinfectant, the preparation method comprising the following steps:
[0018] According to the weight ratio of wound disinfectant raw materials, dissolve icodextrin, chlorhexidine gluconate / hyaluronic acid in a certain amount of water, stir evenly, add the remaining water to make up the volume, and automatically pack the above liquids After sealing, the finished product is obtained after passing the test.
Embodiment 1
[0021] A wound disinfectant solution containing icodextrin, comprising the following components by mass percentage: icodextrin 3%, chlorhexidine gluconate 0.01%, hyaluronic acid 0.05%, and the balance is sterile water, according to the formula Take the mass of each substance, dissolve icodextrin, chlorhexidine gluconate / hyaluronic acid in a certain amount of sterile water, stir evenly, add the remaining sterile water to constant volume, and automatically fill the liquid After packaging, it is sealed, and the finished product is obtained after passing the test.
Embodiment 2
[0023] A wound disinfectant containing icodextrin, comprising the following composition by mass percentage: 5% icodextrin, 0.05% chlorhexidine gluconate, 1% hyaluronic acid, and the balance is water for injection, weighed according to the formula The quality of each substance, after dissolving icodextrin, chlorhexidine gluconate / hyaluronic acid in a certain amount of water for injection, stir evenly, add the remaining water for injection to make up the volume, automatically pack the above liquids and seal them , after passing the test, the finished product is obtained.
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Abstract
The invention provides a wound disinfectant and a preparation method thereof. The wound disinfectant is characterized in that the raw materials of the wound disinfectant include 1%-20% of icodextrin in the total weight of the raw materials, and also include chlorhexidine digluconate, hyaluronic acid and water. The preparation method includes the following steps: dissolving icodextrin, chlorhexidine gluconate/hyaluronic acid in a certain amount of water according to the weight ratio of the raw materials of the wound disinfectant, performing even stirring, adding the remaining water until a constant volume, performing automatic canning, subpackage and sealing on the liquid, and performing detection so as to obtain the qualified finished product. The wound disinfectant is capable of cleaningand disinfecting surgical or accidental wounds, and has the effect of promoting healing of the wounds and preventing scars, the raw materials are selected and matched reasonably, the raw materials areeasily available, the cost is low, the preparation method is simple, and the wound disinfectant is suitable for large-scale industrial production.
Description
technical field [0001] The invention belongs to the technical field of disinfectant, and in particular relates to a wound disinfectant and a preparation method thereof. Background technique [0002] Wounds can be defined as skin defects caused by mechanical, electrical, thermal, chemical and other factors or due to physiological abnormalities. Wound infection is still a terrible and expensive complication. Therefore, reasonable and timely wound debridement and disinfection are extremely important. However, the wound disinfectant currently on the market only has basic debridement or disinfection effects, and does not have other effects. For example, the disinfectant mentioned in the patent CN106421180A "An anti-pus wound disinfectant" only has the effect of cleaning and disinfection . [0003] Icodextrin is a kind of dextran obtained by hydrolysis of starch, which has good water solubility, safety and biocompatibility. Pharmaceutical preparations made of icodextrin have bee...
Claims
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