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Medicinal preparation and medical instrument

A technology for medical devices and pharmaceutical preparations, which can be used in drug combination, drug delivery, inhalers, etc., to solve problems such as patient discomfort and anaphylactic shock

Inactive Publication Date: 2020-11-06
DR C MEDICAL MEDICINE CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There are also risks such as anaphylactic shock caused by direct systemic administration of the antigen that is the cause of the allergy, and the dose needs to be gradually increased from small amounts
In addition, desensitization therapy requires not only long-term treatment, but also patient discomfort due to injection

Method used

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  • Medicinal preparation and medical instrument
  • Medicinal preparation and medical instrument
  • Medicinal preparation and medical instrument

Examples

Experimental program
Comparison scheme
Effect test

manufacture example 1

[0228] Production example 1: Production of composite particles

[0229] In this production example, titanium oxide powder, silver powder, and hydroxyapatite powder were used as raw material powders to produce a composite material each containing one or more titanium oxide particles, one or more silver particles, and one or more hydroxyapatite particles. Composite particles.

[0230] In this production example, two types of composite particles M1 and M2 were produced. Composite particles M1 and M2 differ in the proportions of titanium oxide, silver, and hydroxyapatite contained therein. Composite particles M1 and M2 were produced in the same method as "earthplus" (trade name) manufactured and sold by Shinsyu Ceramics Co., Ltd. . The manufacture of composite particles M1 and M2 was entrusted to Shinsyu Ceramics Co.,Ltd.

[0231] The raw material powders shown in Table 1 were provided. The particle diameter of the titanium oxide powder is a value measured using a transmissi...

manufacture example 2

[0248] Production example 2: Production of nonwoven fabric with composite particles

[0249] A binder resin was added to the suspension (slurry) of the composite particles M1 obtained in Production Example 1 to prepare a mixed solution, and then a polyester spunbonded nonwoven fabric was immersed in the mixed solution to impregnate the nonwoven fabric with the mixed solution. After impregnation, the nonwoven fabric was removed from the mixture and pressed with rollers to squeeze out excess mixture. After pressing, the nonwoven fabric was dried at about 130° C. for about 1 minute, thereby producing a composite particle-attached nonwoven fabric N1. As the binder resin, polyurethane resin (C 3 h 7 NO 2 / NH 2 COOC 2 h 5 ).

[0250] By adjusting the concentration of the composite particles M1 and the binder resin in the mixed solution, the composite particles attached to the non-woven fabric N1 per unit area of ​​the composite particles M1 and the total adhesion amount of ...

manufacture example 3

[0259] Production Example 3: Production of Composite Particle Adhesive Sheet

[0260] The composite particle-attached nonwoven fabric produced in Production Example 2 was cut to produce a strip-shaped composite particle-attached sheet having a width of 1 cm and a length of 10 cm. As the composite particle-attached nonwoven fabric, use wherein the total adhesion amount (total fixation amount) of the composite particle M1 and the binder resin is 4 g / m 2 The composite particles are attached to the nonwoven N1.

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Abstract

The present invention addresses the problem of providing a medicinal preparation that is to be administered to the nasal mucosa for preventing or treating allergic conjunctivitis. Provided is a medicinal preparation for preventing or treating allergic conjunctivitis, said medicinal preparation being to be administered to the nasal mucosa and containing a composite particle which comprises one or more titanium oxide particles, one or more metal particles and one or more calcium phosphate particles. Also provided is a medical instrument for preventing or treating allergic conjunctivitis, said medical instrument comprising an air-permeable mask part covering the nostrils of a user with need of the prevention or treatment of allergic conjunctivitis, ear hook parts formed in the air-permeable mask part and a composite particle detachably adhered to the air-permeable mask part, wherein the composite particle comprises one or more titanium oxide particles, one or more metal particles and oneor more calcium phosphate particles.

Description

technical field [0001] The present invention relates to a medical device for preventing or treating allergic conjunctivitis, a method for preventing or treating allergic conjunctivitis, a medical device for use in a method for preventing or treating allergic conjunctivitis, which is administered to the intranasal mucosa Composite granules, and uses of the composite granules in the preparation of pharmaceutical preparations for preventing or treating allergic conjunctivitis. Background technique [0002] Allergic conjunctivitis is a disease caused by the reaction of the autoimmune system in the body to a causative agent in the external environment known as house dust, mites, mold, pollen, and the like. [0003] Drug therapy, desensitization therapy, and the like are known as therapeutic methods for allergic conjunctivitis. [0004] For drug therapy, steroidal anti-inflammatory agents, immunosuppressants, antihistamines, etc. are used, but these agents may cause side effects....

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K33/42A61K9/14A61K9/16A61K9/70A61K33/24A61K33/242A61K33/243A61K33/34A61K33/38A61K47/02A61P27/14A61P37/08A62B18/02A61M15/00
CPCA61K9/70A61K33/42A61P27/14A61K33/24A61K33/38A61K47/02A61K33/34A61K33/00A61M15/00A61K9/14A61P27/02A61P37/08A62B18/02A61K33/242A61K33/243A41D13/11A41D2400/32A61K9/0043
Inventor 冈崎成实
Owner DR C MEDICAL MEDICINE CO LTD