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Amoxicillin complete antigen and preparation method thereof as well as reagent strip and preparation method thereof

A technology of amoxicillin and complete antigen, applied in chemical instruments and methods, biological testing, fibrinogen, etc., can solve the problems of lack and non-immunogenicity, and achieve low production cost, simple and easy preparation method, Use simple effects

Inactive Publication Date: 2020-11-20
深圳市金阅检测科技有限责任公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Since the molecular weight of most small molecular compounds is less than 1000, they are not immunogenic, that is, they lack T cell epitopes and cannot directly induce the production of specific antibodies in animal bodies, etc.

Method used

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  • Amoxicillin complete antigen and preparation method thereof as well as reagent strip and preparation method thereof
  • Amoxicillin complete antigen and preparation method thereof as well as reagent strip and preparation method thereof
  • Amoxicillin complete antigen and preparation method thereof as well as reagent strip and preparation method thereof

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Embodiment Construction

[0030] The technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the accompanying drawings in the embodiments of the present invention. Apparently, the described embodiments are part of the embodiments of the present invention, not all of them. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the protection scope of the present invention.

[0031] It should also be understood that the terminology used in the description of the invention is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. As used in this specification and the appended claims, the singular forms "a", "an" and "the" are intended to include plural referents unless the context clearly dictates otherwise.

[0032] It should also be further understood that the term "a...

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Abstract

The invention discloses an amoxicillin complete antigen and a preparation method thereof as well as a reagent strip and a preparation method thereof. In the amoxicillin complete antigen, an antigenicdeterminant of an amoxicillin molecule can be fully exposed and has relatively complete spatial conformation, so that the amoxicillin complete antigen provided by the invention has relatively good immunogenicity and can be used for immunoassay. According to the colloidal gold immunochromatography reagent strip for detecting amoxicillin and the preparation method thereof, the reagent strip has relatively high amoxicillin detection sensitivity, the detection time is short, and the detection reagent strip is simple, economical and convenient to use.

Description

technical field [0001] The invention relates to the field of biomedical materials, in particular to a complete antigen of amoxicillin and a preparation method thereof, and a reagent strip for detecting amoxicillin and a preparation method thereof. Background technique [0002] Immunoassay is a trace analysis method based on specific recognition and reversible binding reaction between antigens and antibodies, which is not only suitable for the detection of macromolecular compounds (such as proteins, nucleic acids, bacteria), but also for small molecular compounds ( Such as hormones, drugs) determination. The key to establishing an immunoassay method for small molecule compounds is to be able to prepare antibodies with high affinity and high selectivity for small molecule compounds. Since the molecular weight of most small molecular compounds is less than 1000, they do not have immunogenicity, that is, they lack T cell epitopes and cannot directly induce animal bodies and the...

Claims

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Application Information

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IPC IPC(8): C07K14/435C07K14/765C07K14/77C07K14/795C07K14/47C07K14/75G01N33/558G01N33/532G01N33/53
CPCC07K14/435C07K14/4717C07K14/75C07K14/765C07K14/77C07K14/795G01N33/5308G01N33/532G01N33/558
Inventor 张伟涛蒋永青黄斌刘明如
Owner 深圳市金阅检测科技有限责任公司
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