A device for separating and extracting plasma or serum exosomes
An extraction device and exosome technology, applied in the field of nano-biological extraction, can solve the problems of low purity and low efficiency of exosome separation and extraction, and achieve the effect of accelerating the filtration speed
Inactive Publication Date: 2021-10-01
唐浩
View PDF0 Cites 1 Cited by
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
[0003] The technical problem to be solved by the present invention is to provide a plasma or serum exosome separation and extraction device, which solves the problems of low efficiency and low purity of exosome separation and extraction
Method used
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View moreImage
Smart Image Click on the blue labels to locate them in the text.
Smart ImageViewing Examples
Examples
Experimental program
Comparison scheme
Effect test
Embodiment Construction
[0019] Combine below Figure 1-8The present invention is described in detail, wherein, for the convenience of description, the orientations mentioned below are defined as follows: figure 1 The up, down, left, right, front and back directions of the projection relationship itself are the same.
[0020] combined with Figure 1-8 The plasma or serum exosome separation and extraction device includes a protective shell 10, and the protective shell 10 is provided with an equipment cavity 11, and the equipment cavity 11 contains a separation and extraction mechanism 110, which is located in the equipment cavity 11 The protective shell 10 at the rear end is provided with a first active rotating shaft 48 for rotation, and a long ratchet 53 is fixed on the first active rotating shaft 48, and a centrifugal disc 47 is fixed on the long ratchet 53, and the centrifugal disc 47 A circle of four centrifuge tubes 24 is arranged in turn, the feeding port of the centrifuge tube 24 is at the fr...
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More PUM
| Property | Measurement | Unit |
|---|---|---|
| diameter | aaaaa | aaaaa |
Login to View More
Abstract
The invention discloses a device for separating and extracting plasma or serum exosomes, which includes a protective shell, and the protective shell is provided with an equipment cavity. The clear liquid is separated by ultrafiltration. During the separation, the present invention can pressurize the filter tube to improve the efficiency, and can also regularly reverse the pressure to ensure that the filter screen is not blocked, greatly speeding up the filtration speed and the purity of the filtration, and filtering After the end, the exosomes and other waste liquids can be stored separately to ensure that the exosomes are not contaminated. This equipment can also ensure that the low temperature is maintained during the separation and extraction process. The experimenter can choose to obtain the exosomes immediately or temporarily store the exosomes. body, the built-in test tubes of the present invention can be taken out separately, so as to ensure that the contents of each stage can be checked at any time, and the operation is simple and convenient for research.
Description
technical field [0001] The invention relates to the field of nano-biological extraction, in particular to a plasma or serum exosome separation and extraction device. Background technique [0002] Exosome is a small vesicle with a diameter between 30 and 100nm. It is widely distributed in various body fluids and can carry protein and transport RNA. It plays an important role. Because of its special structure and function, it has great potential. There are many methods for the separation and extraction of exosomes, but no matter which method, the steps are very cumbersome, and the amount of each operation is not large, and the purity is also different. It is not worth the slow research progress caused by the low efficiency and purity of body extraction, so it is necessary to design a fast, convenient and efficient equipment. Contents of the invention [0003] The technical problem to be solved by the present invention is to provide a plasma or serum exosome separation and e...
Claims
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More Application Information
Patent Timeline
Login to View More Patent Type & Authority Patents(China)
IPC IPC(8): C12M1/12C12M1/00
CPCC12M33/10C12M33/14C12M39/00C12M47/04
Inventor 高萌傅云峰唐浩戴金凤
Owner 唐浩