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Traditional Chinese medicine composition for treating intractable cough and asthma as well as preparation process and quality control method thereof

A composition and refractory technology, applied in the direction of drug combination, pharmaceutical formula, medical preparations containing active ingredients, etc., can solve the problems of unclear pathogenesis, lack of intractable cough and asthma, adverse reactions and drug resistance, etc. Achieve the effect of good repeatability and harmonize drug properties

Active Publication Date: 2021-01-08
SHANGHAI UNIV OF T C M
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

As a threat to human health, many countries pay more attention to the treatment of cough and asthma. At the same time, scholars at home and abroad have also conducted more in-depth research on cough and asthma, but the pathogenesis of the disease is still unclear
In recent years, inhaled glucocorticoids and β2 receptor agonists are commonly used drugs for the treatment of cough and asthma, but these drugs have obvious adverse reactions and drug resistance, and are not suitable for long-term use
Traditional Chinese medicine has a long history of treating cough and asthma, and has a good clinical effect. Some Chinese patent medicines have been listed on the market, but there is still a lack of effective Chinese patent medicines for the treatment of intractable cough and asthma.

Method used

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  • Traditional Chinese medicine composition for treating intractable cough and asthma as well as preparation process and quality control method thereof
  • Traditional Chinese medicine composition for treating intractable cough and asthma as well as preparation process and quality control method thereof
  • Traditional Chinese medicine composition for treating intractable cough and asthma as well as preparation process and quality control method thereof

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Effect test

Embodiment 1

[0039] Embodiment 1 The present invention treats the Chinese medicine composition (1) of intractable cough and asthma

[0040] 10 parts by weight of raw ephedra, 12 parts by weight of Scutellaria baicalensis, 10 parts by weight of dried ginger, 3 parts by weight of Asarum, 10 parts by weight of gentian, 10 parts by weight of myrobalan, 10 parts by weight of raw licorice, decocted in a conventional method.

Embodiment 2

[0041] Embodiment 2 The present invention treats the Chinese medicine composition (two) of intractable cough and asthma

[0042] 12 parts by weight of raw ephedra, 15 parts by weight of Scutellaria baicalensis, 9 parts by weight of dried ginger, 3 parts by weight of Asarum, 9 parts by weight of gentian, 12 parts by weight of myrobalan, 6 parts by weight of raw licorice, decocted in a conventional method.

Embodiment 3

[0043] Embodiment 3 The present invention treats the Chinese medicine composition of intractable cough and asthma (three)

[0044] 12 parts by weight of raw ephedra, 16 parts by weight of Scutellaria baicalensis, 12 parts by weight of dried ginger, 3 parts by weight of Asarum, 9 parts by weight of gentian, 12 parts by weight of myrobalan, 13 parts by weight of raw licorice, decocted in a conventional method.

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Abstract

The invention relates to a traditional Chinese medicine composition for treating intractable cough and asthma as well as a preparation process and a quality control method thereof. The traditional Chinese medicine composition is prepared from the following raw material medicines of 10-13 parts by weight of raw ephedra, 12-16 parts by weight of radix scutellariae, 9-13 parts by weight of dried ginger, 3-10 parts by weight of herba asari, 9-12 parts by weight of radix gentianae, 10-15 parts by weight of roasted fructus chebulae and 6-13 parts by weight of raw liquorice roots. The invention proves that the weight proportion relationship of the raw materials of the traditional Chinese medicine composition has obvious influence on the curative effect of treating intractable cough and asthma, and a prescription should be made strictly according to the weight proportion. The invention further optimizes the preparation process of the traditional Chinese medicine composition granules, establishes a fingerprint detection method of the traditional Chinese medicine composition granules and a method for simultaneously detecting the contents of multiple components in the traditional Chinese medicine composition sample, and provides a systematic research basis for reasonable development of the traditional Chinese medicine composition compound preparation.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for treating intractable cough and asthma, a preparation process and a quality control method thereof. Background technique [0002] Obstinate cough and asthma is a collective term for persistent cough and dyspnea, and is a common clinical chronic respiratory disease, which can occur at any age. Clinically, it is mainly characterized by wheezing, oppression, coughing and expectoration, cyanosis of the lips and nails, fullness in the abdomen, lingering course of the disease, and prolonged difficulty in recovery. Modern medicine diagnoses cough variant asthma, allergic asthma, chronic obstructive pulmonary disease and so on. [0003] Intractable cough and asthma belong to the category of "cough", "cough and asthma", "wheezing" and "phlegm and asthma" in traditional Chinese medicine. As early as more than two thousand years ago,...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61K9/16A61P11/14A61P11/06G01N30/02G01N30/06G01N30/30G01N30/32G01N30/34G01N30/74
CPCA61K36/17A61K36/539A61K36/9068A61K36/268A61K36/515A61K36/185A61K36/484A61K9/1652A61P11/14A61P11/06G01N30/02G01N30/06G01N30/30G01N30/32G01N30/34G01N30/74A61K2236/331A61K2236/39A61K2236/51G01N2030/324A61K2300/00Y02A50/30
Inventor 邹纯朴王庆其张彤丁越李孝刚梁尚华李婷王少墨裘世轲
Owner SHANGHAI UNIV OF T C M