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Implants using ultrasonic communication for neural sensing and stimulation

一种神经、超声波的技术，应用在植入刺激器、脊髓神经电极、利用振动的流体等方向，能够解决副作用等问题

Pending Publication Date: 2021-01-26
IOTA BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This implanted device is also implanted to stimulate upstream nerves, such as the vagus nerve, which leads to significant side effects due to off-target electrical stimulation

Method used

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  • Implants using ultrasonic communication for neural sensing and stimulation
  • Implants using ultrasonic communication for neural sensing and stimulation
  • Implants using ultrasonic communication for neural sensing and stimulation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0165] Embodiment 1, an implantable medical device, comprising:

[0166] a body including an ultrasonic transducer configured to receive ultrasonic waves and convert energy from the ultrasonic waves into electrical energy for powering the device;

[0167] two or more electrodes in electrical communication with the ultrasound transducer; and

[0168] A clip is attached to the body, the clip is configured to at least partially surround the nerve and position the two or more electrodes in electrical communication with the nerve.

Embodiment 2

[0169] Embodiment 2. The implantable medical device of Embodiment 1, wherein the clip is configured to at least partially surround the nerve and the filamentary tissue attached to the nerve.

Embodiment 3

[0170] Embodiment 3. The implantable medical device of embodiment 2, wherein the filamentous tissue is a blood vessel.

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PUM

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Abstract

Described herein is an implantable medical device that includes a body having one or more ultrasonic transducers configured to receive ultrasonic waves and convert energy from the ultrasonic waves into an electrical energy, two or more electrodes in electrical communication with the ultrasonic transducer, and a clip attached to the body that is configured to at least partially surround a nerve and / or a filamentous tissue and position the two or more electrodes in electrical communication with the nerve. In certain examples, the implantable medical device includes two ultrasonic transducers with orthogonal polarization axes. Also described herein are methods for treating incontinence in a subject by converting energy from ultrasonic waves into an electrical energy that powers a full implanted medical device, and electrically stimulating a tibial nerve, a pudendal nerve, or a sacral nerve, or a branch thereof, using the fully implanted medical device.

Description

[0001] Cross References to Related Applications [0002] This application claims the benefit of priority to U.S. Provisional Patent Application No. 62 / 660,112, filed April 19, 2018, which is hereby incorporated by reference for all purposes. technical field [0003] The present invention relates to implantable medical devices powered by ultrasound and methods of using the implantable medical devices. Background technique [0004] The individual's peripheral nervous system manipulates the activity and physiological homeostasis of vital organs under tightly controlled conditions. Electrical impulses sent through nerves can alter, for example, pulse rate, inflammation, and bladder or bowel control. Certain medical conditions can arise when these nerve signals do not properly control the body through overstimulated or understimulated target organs. [0005] Invasive methods have been developed for treating abnormal physiological activity by manipulating electrical signals in t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61N1/36
CPCA61B5/0205A61B5/202A61B5/686A61B5/6877A61N1/05A61N1/0556A61N1/37282A61N1/0456A61N1/36053B06B1/0648A61N1/37276A61B5/4836A61B5/6884A61N1/36007A61N1/37217A61N1/3605A61B5/294A61N1/3787A61B5/14503A61B5/14532A61B5/14542A61B2560/0219
Inventor M·M·马哈贝兹R·尼利J·凯伊J·M·卡梅纳
Owner IOTA BIOTECH
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