A kind of pharmaceutical composition containing benzalkonium chloride, preparation method and application thereof

Abstract

The invention relates to a pharmaceutical composition containing benzalkonium chloride, a preparation method and an application thereof. The pharmaceutical composition containing benzalkonium chloride specifically includes the following raw materials in parts by weight: 40 parts by weight of benzalkonium chloride; 40 parts by weight of urea ~60 parts; the preparation method is as follows: after weighing each component according to parts by weight, mix them evenly to obtain. The invention not only expands the use of benzalkonium chloride, but also develops a pharmaceutical composition, which can not only effectively treat the foot rot of livestock, but also effectively reduce the microbial pollution on the carcass surface during poultry slaughter.

Description

technical field [0001] The invention belongs to the field of veterinary medicine, and in particular relates to a pharmaceutical composition containing benzalkonium chloride, a preparation method and an application thereof. Background technique [0002] Benzalkonium chloride is a quaternary ammonium-based cationic surfactant, used as a broad-spectrum fungicide, used for indoor and equipment disinfection, with algicidal, bactericidal, fungicidal and virucidal properties; Low, in order to make full use of the bactericidal effect of benzalkonium chloride and expand the use of benzalkonium chloride, our company has done many researches on the application of benzalkonium chloride. [0003] Foot rot is a common disease in ruminants, especially sheep, goats and cattle breeding. It is characterized by purulent and necrotic decomposition of hoof tissue, putrefaction and stench, and destruction of cutin, which is shed from epidermal tissue. Its sickness rate is relatively high, about ...

AI Technical Summary

Problems solved by technology

The current treatment drugs and methods are mainly to use bactericides such as copper sulfate solution in the footwashing pool for medicated bath cleaning, but the effect is not good, and it has become a common disease in the breeding industry. In order to expand the application of benzalkonium chloride, our company Attempt to apply benzalkonium chloride to the medicated bath of livestock foot rot in order to obtain good results, but it was found that: 1) the bactericidal and antibacterial effect of benzalkonium chloride on the rot of the hoof is not ideal, 2) with the The bactericidal and antibacterial effect of benzalkonium chloride still has a significant decline with the increase in the number of times of use of medicated bath liquid

[0004] In addition, in the research on how to reduce the pollution of poultry carcasses by pathogenic bacteria, the R&D personnel of the company have done many researches, including using benzalkonium chloride to strictly disinfect the slaughtering environment and utensils, etc. in order to obtain good results, but The results are not satisfactory

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