A kind of sucrose-6-ester production device and production method

Abstract

The invention belongs to the technical field of sucrose-6-ester production, in particular to a sucrose-6-ester production device and a production method, which solves the problem that a large amount of non-polar auxiliary is needed in the sucrose-6-ester synthesis method in the prior art. Solvent or gas (or solvent vapor) that can remove water causes problems such as reduced production efficiency and increased by-products. The sucrose-6-ester production device includes: a distillation tank, a right side cover, a storage tank, a reaction tank, and a cooling tank. Water collection tank, heating column, heating scraper group; the distillation tank is set horizontally, its right end is open, the top of the distillation tank is provided with a feed pipe and a vacuum pump connection port 1, and the bottom of the distillation tank is provided with a water outlet pipe and a discharge pipe. tube one. In the present invention, the first reaction mixture is evaporated to remove water at low pressure by forming a vacuum environment in the distillation tank, avoiding the use of gas or solvent vapor capable of removing water in this link, effectively reducing the process flow and production cost.

Description

technical field [0001] The invention relates to the technical field of sucrose-6-ester production, in particular to a sucrose-6-ester production device and production method. Background technique [0002] Sucrose-6-ester is an important intermediate in the synthesis of artificial sweetener sucralose. One method of synthesizing sucrose-6-ester is: in a polar aprotic solvent, such as N,N-dimethyl In formamide, reacting sucrose with an organotin-based acylation accelerator, while continuously adding a non-polar co-solvent capable of removing water by co-distillation, and removing water by co-distillation, thereby providing a substantially water-free reaction mixture, The carboxylic anhydride is then added to the reaction mixture and the resulting reaction mixture is incubated for a period of time sufficient to produce the sucrose 6 ester. This method requires the use of a large amount of non-polar co-solvent, which must be dried before addition, and then recovered and re-dried...

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Problems solved by technology

[0004] The purpose of the present invention is in order to solve the existence of sucrose-6-ester synthesis method in the prior art and needs to use a large amount of non-polar auxiliary solvents or the gas (or solvent vapor) that can remove water, causes production efficiency to reduce, by-product increases etc. problem, and a kind of sucrose-6-ester production device and production method proposed

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