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Natural plant biological enzyme conversion acne prevention and treatment external preparation as well as preparation method and application thereof

A technology of natural plants and external preparations, applied in the direction of plant raw materials, medical preparations containing active ingredients, plant/algae/fungus/moss ingredients, etc., can solve the problems of slow relative action, limited actual effect, poor skin utilization, etc. , to achieve the effect of balancing oil secretion, eliminating skin inflammation, removing garbage and toxins

Inactive Publication Date: 2021-05-07
CHENGDU UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For example, the use of hormone drugs such as diethylstilbestrol, antibiotics such as gentamicin, macrolide antibiotics, tetracycline, etc., this type of treatment has a certain effect, but the side effects are relatively large, the cure rate is low, and it is easy to relapse after recovery , and most of them are chemical agents and hormonal drugs, which are prone to side effects after use
There are also reports of using traditional Chinese medicine compound treatment, but the actual effect is limited, the skin utilization is relatively poor, and the relative effect is slow

Method used

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  • Natural plant biological enzyme conversion acne prevention and treatment external preparation as well as preparation method and application thereof
  • Natural plant biological enzyme conversion acne prevention and treatment external preparation as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] A natural plant biological enzyme conversion external preparation material for acne prevention and treatment, comprising: 20 parts of Sophora flavescens, 15 parts of Salvia miltiorrhiza, 15 parts of water shield, 10 parts of Centella asiatica, 5 parts of ginkgo biloba, 5 parts of mugwort leaves, and 5 parts of purslane in parts by weight. 5 parts of mangosteen, 5 parts of skullcap, 5 parts of Moutan bark, 3 parts of licorice, 2 parts of thyme and 1 part of menthol.

[0038] Preparation:

[0039] (1) Using PDA medium for Mucor luteus CAA09-2, at 28°C and 80rpm, the bacteria were propagated and cultured, and when the bacteria were in the logarithmic phase of logarithmic growth, the bacteria were collected by centrifugation;

[0040] (2) Grinding the raw material into 80-mesh powder, adding the pulverized raw material to 0.1mol / L sodium dihydrogen phosphate buffer solution (pH is 6.0) at a volume ratio of 1:10 to prepare a reaction solution, and then The microorganisms ar...

Embodiment 2

[0044] A natural plant bioenzyme transformation external preparation material for acne prevention and treatment, comprising: 10 parts of Sophora flavescens, 10 parts of Salvia miltiorrhiza, 10 parts of water shield, 15 parts of Centella asiatica, 10 parts of ginkgo biloba, 10 parts of mugwort leaves, and 7 parts of purslane in parts by weight. 7 parts of mangosteen, 7 parts of skullcap, 7 parts of Moutan bark, 2 parts of licorice, 3 parts of thyme and 1 part of menthol.

[0045] Preparation:

[0046] (1) Using PDA culture medium for Mucor roserii CAA09-2, at 28°C and 100rpm, the bacteria were propagated and cultivated, and when the bacteria were in the logarithmic phase of logarithmic growth, the bacteria were collected by centrifugation;

[0047] (2) Grinding the raw material into 80-mesh powder, adding the pulverized raw material to 0.1mol / L sodium dihydrogen phosphate buffer solution (pH is 6.0) at a volume ratio of 1:10 to prepare a reaction solution, and then The microor...

Embodiment 3

[0051] A natural plant biological enzyme conversion external preparation material for acne prevention and treatment, comprising: 15 parts of sophora flavescens, 20 parts of salvia miltiorrhiza, 20 parts of water shield, 20 parts of centella asiatica, 5 parts of ginkgo biloba, 15 parts of mugwort leaves, and 10 parts of purslane in parts by weight. 10 parts of mangosteen, 10 parts of skullcap, 10 parts of Moutan bark, 5 parts of licorice, 5 parts of thyme and 2 parts of menthol.

[0052] Preparation:

[0053] (1) Using PDA culture medium for Mucor ruckeri CAA09-2, at 28° C. and 90 rpm, the bacteria were propagated and cultured, and when the bacteria were in the logarithmic phase of logarithmic growth, the bacteria were collected by centrifugation;

[0054] (2) Grinding the raw material into 80-mesh powder, adding the pulverized raw material to 0.1mol / L sodium dihydrogen phosphate buffer solution (pH is 6.0) at a volume ratio of 1:10 to prepare a reaction solution, and then The...

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Abstract

The invention discloses a natural plant biological enzyme converted acne prevention and treatment external preparation as well as a preparation method and application thereof, and belongs to the technical field of cosmetics. The external preparation comprises the following components in parts by weight of 10-20 parts of radix sophorae flavescentis, 10-20 parts of radix salviae miltiorrhizae, 10-20 parts of brasenia schreberi, 10-20 parts of asiatic pennywort herb, 5-15 parts of gingko, 5-15 parts of folium artemisiae argyi, 5-10 parts of herba portulacae, 5-10 parts of garcinia bark, 5-10 parts of radix scutellariae, 5-10 parts of moutan bark, 2-5 parts of radix glycyrrhizae, 2-5 parts of thyme and 1-2 parts of menthol. According to the external preparation, the formula is scientific, and the bioavailability of plants is improved through conversion of a biological enzyme technology; the plant formula which is relatively high in curative effect and has the effects of removing acnes, killing bacteria, diminishing inflammation, controlling oil, conditioning skin and repairing scars is obtained, a preparation which is suitable for patients with different skin types according to physiological characteristics of the skin is prepared, no scars exist on the skin after acne is eliminated, no toxic or side effect exists, use is convenient, skin microcirculation can be effectively improved, grease secretion is balanced, cell metabolism is enhanced, and garbage and toxins in the skin are thoroughly removed, so that the skin inflammation is quickly eliminated.

Description

technical field [0001] The invention belongs to the technical field of cosmetics, and in particular relates to an external preparation for preventing and treating acne by natural plant bio-enzyme conversion and its preparation method and application. Background technique [0002] Acne is a chronic inflammatory skin disease of the pilosebaceous unit. It mainly occurs in adolescents. The main reason is that the body is full of yang heat, the blood heat surges out, and the blood is melancholy. The clinical manifestations are acne, papules, and pus on the face. It is characterized by pleomorphic skin lesions such as blisters and nodules. The microbiota on the surface of acne is out of balance, and bacterial infection produces inflammation, which repeatedly stimulates the hyperplasia of connective tissue in the skin and produces scars, which makes the patients unbearable itching and pain, and brings mental pain. Many countries have invested a large amount of funds for research a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/65A61K36/71A61K9/06A61K47/44A61P17/10A61P31/04A61K31/045
CPCA61K9/06A61K31/045A61K36/16A61K36/185A61K36/23A61K36/282A61K36/38A61K36/484A61K36/489A61K36/53A61K36/537A61K36/539A61K36/62A61K36/65A61K36/71A61K47/44A61K2236/19A61P17/10A61P31/04A61K2300/00
Inventor 蒋用何正有汤秀强李佳毕建军高鑫
Owner CHENGDU UNIV
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