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Extensible flexible electrode transfer method based on elastic seal containing fluid channel

A fluid channel and flexible electrode technology, which is applied in the field of biomedical engineering, can solve the problems of difficult control of the relative position of electrode points and difficult operation, and achieve the effect of solving repeated attachment and uncovering repositioning and improving reliability

Active Publication Date: 2021-06-18
NORTHWESTERN POLYTECHNICAL UNIV
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Problems solved by technology

This method has very important practical value and innovative significance for accurately obtaining the stable cortical EEG signal of the coordinates of the target brain area. It can effectively solve the difficulty in the current discrete and extensible flexible electrode attachment operation, and the relative position of the electrode points is not easy to control. The problem

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  • Extensible flexible electrode transfer method based on elastic seal containing fluid channel
  • Extensible flexible electrode transfer method based on elastic seal containing fluid channel
  • Extensible flexible electrode transfer method based on elastic seal containing fluid channel

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specific Embodiment

[0055] The transfer process of the extensible flexible electrode based on the fluid channel elastic stamp is mainly divided into the following four steps:

[0056] In the first step, the elastic stamp 1 containing the fluid channel is pressed on the stretchable flexible electrode 2, and the exposed electrode points of the stretchable flexible electrode 2 are laid down on the surface of the glass substrate 3, and the water-soluble rapidly degradable material solution 4 is injected into the fluid channel , the solution contacts the extensible flexible electrode 2 through the array of small circular holes at the bottom of the elastic stamp 1 containing fluid channels;

[0057] Here, the water-soluble rapidly degradable material solution 4 is selected from polyethylene glycol (PEG) solution, and the injection volume is related to the size of the elastic stamp 1 containing the fluid channel. ;

[0058] In the second step, put the whole in an oven at 70-80 degrees Celsius and heat ...

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Abstract

The invention discloses an extensible flexible electrode transfer method based on an elastic seal containing a fluid channel. The method comprises the following steps: firstly pressing the elastic seal on an extensible flexible electrode, and injecting a water-soluble rapid degradation material solution into the fluid channel; then heating and drying the solution, and enabling the extensible flexible electrode to be lifted up from a glass substrate by the elastic seal through adhesion; then, transferring the elastic seal with the extensible flexible electrode attached to the bottom face to the position above a target brain area through a micro-motion platform, injecting artificial cerebrospinal fluid into the fluid channel, and gradually dissolving a degradation material; finally, after the degradable material is completely dissolved, separating the elastic seal from the extensible flexible electrode so as to enable the extensible flexible electrode to be stably attached to the surface of the cerebral cortex. The method has very important practical value and innovative significance for accurately acquiring stable electrocorticogram signals of target brain area coordinates, and can effectively solve the problems that attaching operation difficulty of an discretized extensible flexible electrode of the electrode point at present is large and the relative position of the electrode point is not easy to control.

Description

technical field [0001] The invention belongs to the technical field of biomedical engineering, and in particular relates to an extensible flexible electrode transfer method. Background technique [0002] The development and integration of microelectromechanical systems (MEMS) technology and flexible electronics technology provides an important guarantee for the development of high-precision brain science research tools. Among them, cortical brain electrodes are an extremely important category. In order to improve the adhesion between the electrodes and the sulcus-shaped cortical surface, strip-shaped electrodes or grid-shaped electrodes with flexible polymer substrates are often used. However, due to the combination of high-frequency vascular and low-frequency respiratory pulsations, as well as brain movements caused by body movements, higher requirements are placed on the compliance of electrodes. [0003] The machinability of flexible polymer substrate electrodes is good,...

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B5/291A61B5/257
Inventor 吉博文周宇昊常洪龙冯慧成张凯熊俊彦
Owner NORTHWESTERN POLYTECHNICAL UNIV
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