Gene detection kit of endometriosis Pap smear sample and method for judging deterioration degree of endometriosis

A technique for Pap smear and endometriosis, applied in the fields of genomics, biochemical equipment and methods, microbial determination/inspection, etc.
CN113030482APending Publication Date: 2021-06-25SUN YAT SEN UNIV +1
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
SUN YAT SEN UNIV
Publication Date
2021-06-25

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Abstract

The present invention relates to a gene detection kit of an endometriosis Pap smear sample and a method for judging the deterioration degree of endometriosis. According to the gene detection kit and the in-vitro detection method thereof, at least nine antibodies are used, the specific genotype of the specific SNP site and the expression quantity of at least one of mutually reacted gene products can be qualitatively detected in vitro in a non-invasive manner, and the deterioration degree of endometriosis can be accurately judged; further, the gene detection kit is applied to in-vitro detection of an endometriosis pasteur smear sample.
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Description

technical field

[0001] The invention relates to a gene detection kit and its application, in particular to a gene detection kit for in vitro detection of endometriosis Pap smear samples and its use in non-invasive qualitative judgment of endometriosis method of deterioration. Background technique

[0002] Endometriosis is a benign but debilitating gynecological disorder associated with chronic pelvic pain, dysmenorrhea, and infertility. About 10% of women of reproductive age are affected by endometriosis, which causes abnormal growth of endometrium-like tissues outside the uterine cavity. These growths on the benign peritoneal surface invade ectopically, mimicking the development of malignant metastases, and are accompanied by angiogenesis and cell migration. Histopathological observation and gene analysis showed that both endometrioid ovarian cancer and clear cell ovarian cancer were derived from endometriosis. Although some hypotheses have been put forward about the eti...

Claims

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