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Mouthwash and preparation method thereof

A mouthwash and formula technology, applied in the field of medicine, can solve problems such as poor experience and comfort, irritation of patients, and gap in curative effect, and achieve good bactericidal performance, avoid irritation, and improve antibacterial effect

Pending Publication Date: 2021-07-23
湖南中医药大学第一附属医院(中医临床研究所)
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] In modern life, due to the needs of health and life social etiquette, it is necessary to keep the mouth clean and avoid bad breath; in addition, people's daily life will cause oral infection, redness, swelling, and ulcers due to factors such as getting angry, infection, and performing radiotherapy and surgery. and other symptoms have brought adverse effects on people's lives and health. In severe cases, it is even difficult to eat, which seriously endangers people's health.
[0003] In order to alleviate these symptoms, people have developed mouthwashes. Most of the existing mouthwashes contain chemical antibacterials, but in order to promote the dispersion of antibacterials in mouthwashes, alcohol is often added to promote the dissolution and Scattered, but the addition of alcohol will also stimulate the patient's mouth, making the experience and comfort poor; and the existing mouthwash with some traditional Chinese medicine ingredients has a certain degree of antibacterial performance compared with the mouthwash of chemical antibacterial drugs. Therefore, it is necessary to find a mouthwash that has good antibacterial properties and can effectively avoid or reduce oral irritation

Method used

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  • Mouthwash and preparation method thereof
  • Mouthwash and preparation method thereof
  • Mouthwash and preparation method thereof

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preparation example Construction

[0035] In the present invention, the preparation method of the mouthwash comprises the following steps: taking each traditional Chinese medicine component of the formula amount, adding it to water, boiling for 20-35min, and collecting the filtrate; adding the filter residue to ethanol and standing for 10-30h, filtering, Collect the alcohol extract; combine the filtrate and the alcohol extract, and distill under reduced pressure to a thick paste to obtain the Chinese medicine extract; then add the Chinese medicine extract, cetylpyridinium chloride, surfactant, sweetener Agent and water are mixed, that is.

[0036] In the present invention, there is also provided a preparation method of another described mouthwash, comprising the steps of:

[0037] A, preparation of alcohol extract: take each Chinese medicine component in proportion, then utilize ethanol to carry out alcohol extraction, filter, collect filter residue and alcohol extract respectively;

[0038] B, preparation of ...

Embodiment 1

[0047] A mouthwash, wherein 1000 parts by weight of the mouthwash includes the following components by weight: 3.5 parts of Chinese medicine extracts, 0.7 parts of cetylpyridinium chloride, and 4 parts of surfactants , 6 parts of sweetener, and the balance is water; the Chinese medicine extract is made from the following Chinese medicine components in parts by weight: 20 parts of honeysuckle, 20 parts of peppermint, 20 parts of Polygonatum odoratum, 15 parts of licorice;

[0048] The preparation method of the mouthwash comprises the following steps: taking each traditional Chinese medicine component of the formula amount, adding it to water, boiling for 30 minutes, and collecting the filtrate; adding the filter residue to ethanol and standing for 24 hours, filtering, and collecting the ethanol extract; combining the filtrate and The alcohol extracts are combined, and distilled under reduced pressure to a thick paste to obtain the Chinese medicine extract; then the Chinese medic...

Embodiment 2

[0050] A mouthwash, wherein 1000 parts by weight of the mouthwash includes the following components by weight: 3.5 parts of Chinese medicine extracts, 0.7 parts of cetylpyridinium chloride, and 4 parts of surfactants , 6 parts of sweetener, and the balance is water; the Chinese medicine extract is made from the following Chinese medicine components in parts by weight: 20 parts of honeysuckle, 20 parts of peppermint, 20 parts of Polygonatum odoratum, 15 parts of licorice;

[0051] Described mouthwash is made through the following steps:

[0052] A, preparation of alcohol extract: take each Chinese medicine component in proportion, then utilize ethanol to carry out alcohol extraction, filter, collect filter residue and alcohol extract respectively;

[0053] B, preparation of water extract: add the filter residue obtained in step A into water, boil water to extract, filter to obtain water extract;

[0054] C, preparation of Chinese medicine extract: the alcohol extract that A st...

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Abstract

The invention discloses a mouthwash. 1,000 parts by weight of the mouthwash comprises the following components in parts by weight: 3-5 parts of a traditional Chinese medicine extract, 0.5-2 parts of cetylpyridinium chloride, 2-5 parts of a surfactant, 3-8 parts of a sweetening agent and the balance water. The traditional Chinese medicine extract is prepared from the following traditional Chinese medicine components in parts by weight: 15-25 parts of honeysuckle, 15-25 parts of mint, 15-25 parts of radix polygonati officinalis and 8-18 parts of liquorice. The invention also provides a preparation method of the mouthwash. The mouthwash has a good anti-microorganism performance, can treat oral infection diseases and effectively remove ozostomia, has a high use comfort level and the like. In addition, the preparation method can improve an anti-microorganism performance of mouthwash.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a mouthwash and a preparation method thereof. Background technique [0002] In modern life, due to the needs of health and life social etiquette, it is necessary to keep the mouth clean and avoid bad breath; in addition, people's daily life will cause oral infection, redness, swelling, and ulcers due to factors such as getting angry, infection, and performing radiotherapy and surgery. Symptoms such as these have brought adverse effects to people's lives and health, and severe cases are even difficult to eat, seriously endangering people's health. [0003] In order to alleviate these symptoms, people have developed mouthwashes. Most of the existing mouthwashes contain chemical antibacterials, but in order to promote the dispersion of antibacterials in mouthwashes, alcohol is often added to promote the dissolution and Scattered, but the addition of alcohol will also stimulate the patient's...

Claims

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Application Information

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IPC IPC(8): A61K8/9794A61K8/9789A61K8/49A61K36/8969A61P1/02A61P31/04A61Q11/00A61K31/44
CPCA61K8/9794A61K8/9789A61K8/4926A61Q11/00A61K36/355A61K36/534A61K36/8969A61K36/484A61K31/44A61P1/02A61P31/04A61K2236/333A61K2236/331
Inventor 陈新宇蔡虎志邓旭陈青扬杨磊林泉成
Owner 湖南中医药大学第一附属医院(中医临床研究所)
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