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Traditional Chinese medicine extract for resisting oral helicobacter pylori, oral care product and preparation methods thereof

A Helicobacter pylori, extract technology, applied in antibacterial drugs, skin care preparations, oral care, etc., can solve the problems of oral mucosal damage, oral flora imbalance, etc., to achieve balance of oral flora, relieve gum redness and swelling , Improve the effect of oral microenvironment

Inactive Publication Date: 2021-09-03
泰投华信(北京)科技发展有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Currently commonly used oral care products such as toothpaste, mouthwash, lozenges and other products are added with antibiotics and disinfectants, such as chlorhexidine gluconate, cetylpyridinium chloride, etc. These ingredients can not only kill harmful bacteria, It can also kill beneficial bacteria, leading to an imbalance of oral flora
There are also some oral care products that use strong irritating ingredients such as thymol, eucalyptus oil, menthol, alcohol, etc. to make the mouth feel fresh temporarily, but long-term use not only causes the imbalance of oral flora, but also has harmful effects on the oral mucosa. certain damage

Method used

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  • Traditional Chinese medicine extract for resisting oral helicobacter pylori, oral care product and preparation methods thereof
  • Traditional Chinese medicine extract for resisting oral helicobacter pylori, oral care product and preparation methods thereof
  • Traditional Chinese medicine extract for resisting oral helicobacter pylori, oral care product and preparation methods thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Embodiment 1. The traditional Chinese medicine extract against oral Helicobacter pylori of this embodiment includes the following components and their parts by weight: 20-40 parts of pueraria, 9-15 parts of Scutellaria baicalensis, 9-15 parts of Coptis chinensis, and 5-15 parts of honeysuckle , 5 to 15 parts of gall, 3 to 10 parts of dandelion, 3 to 10 parts of wild chrysanthemum, and 3 to 5 parts of raw licorice.

Embodiment 2

[0022] Embodiment 2, the preparation method of the traditional Chinese medicine extract against oral Helicobacter pylori of this embodiment, see figure 1 shown, including the following steps:

[0023] S1, eight kinds of Chinese medicine raw materials of Pueraria lobata, Scutellaria baicalensis, Coptis chinensis, honeysuckle, gall, dandelion, wild chrysanthemum, raw licorice are mixed according to the described parts by weight;

[0024] S2. Add 8 to 10 times the volume of deionized water to the raw materials of traditional Chinese medicine and soak for 8 to 15 hours;

[0025] S3. Heating and boiling for 1.5 hours under pressure of 1.05~1.10Kp;

[0026] S4, filter out the medicinal liquid;

[0027] S5, then add deionized water 2 to 6 times the volume of the medicinal dregs to the medicinal dregs and continue to pressurize and boil for 1.5 hours;

[0028] S6, secondary filtration of medicinal liquid;

[0029] S7, the above-mentioned two medicinal liquids are combined and conc...

Embodiment 3

[0032]Embodiment 3. A toothpaste containing an anti-oral Helicobacter pylori Chinese medicine extract and a preparation method thereof of this embodiment are composed of the following components and their weight percentages: 10% of calcium hydrogen phosphate, 12% of silicon dioxide, and 46.5% of wetting agent. %, Anti-Oral Helicobacter pylori Chinese Medicine Extract 2.5%, Sodium Lauryl Sulfate 2.5%, Flavor 1.2%, Sodium Hydroxymethylcellulose 2.0%, Cocamidopropyl Betaine 0.5%, Sodium Saccharin 0.3%, Phenyl Potassium Acid Sodium 0.3%, Titanium Dioxide 0.4%, Water 21.8%.

[0033] The wetting agent is composed of glycerin, sorbitol and polyethylene glycol-8 in a weight ratio of 21:22:2.

[0034] The preparation method of the anti-oral Helicobacter pylori traditional Chinese medicine extract is:

[0035] Add the raw materials of traditional Chinese medicine into deionized water with a volume of 8 to 10 times, soak for 8 to 15 hours, heat and boil for 1.5 hours under the state of ...

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Abstract

The invention discloses a traditional Chinese medicine extract for resisting oral helicobacter pylori, an oral care product and preparation methods thereof. Chinese herbal medicines are taken as main raw materials, so that the problems of side effects, poor experience, low universality and the like due to the facts that the bacterial drug resistance is increased, the oral micro-ecological environment is damaged and pungent taste exists after antibiotic, thymol, thyme powder, eucalyptus oil, ethyl alcohol and other components are used in the prior art. The traditional Chinese medicine extract is prepared from 20-40 parts of radix puerariae, 9-15 parts of radix scutellariae, 9-15 parts of rhizoma coptidis, 5-15 parts of honeysuckle flowers, 5-15 parts of gallnuts, 3-10 parts of dandelions, 3-10 parts of wild chrysanthemum flowers and 3-5 parts of raw licorice roots. After the extract is formed, the extract is added into oral care products such as toothpaste, mouth wash and buccal tablets in proportion. The invention has the effects of killing oral HP bacteria and preventing recurrence of the oral HP bacteria, and is safe, mild, non-irritant and high in universality.

Description

technical field [0001] The invention relates to the technical field of oral cleaning products, in particular to a traditional Chinese medicine extract against oral Helicobacter pylori, an oral care product and a preparation method thereof. Background technique [0002] Helicobacter pylori HP is a microaerophilic gram-negative bacterium. Helicobacter pylori is closely related to the pathogenesis of chronic gastritis, peptic ulcer and gastric cancer. Periarthritis, dental caries, diabetes, cardiovascular disease, etc. are closely related, and "quadruple" therapy is often used to eradicate them in clinical practice. However, more and more evidence points out that in addition to the stomach, the oral cavity is an important place for the accumulation of Helicobacter pylori. The oral cavity and stomach form a microenvironment of microbial symbiosis in the human body, forming the connection between oral flora and intestinal flora. There is a lower redox potential around the denta...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/718A61K9/20A61P31/04A61P31/02A61P1/02A61K8/9789A61K8/98A61Q11/00A61Q17/00A61K35/64
CPCA61K36/488A61K36/539A61K36/718A61K36/355A61K35/64A61K36/288A61K36/287A61K36/484A61K9/2054A61P31/04A61P31/02A61P1/02A61K8/9789A61K8/987A61Q11/00A61Q17/005A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61K2800/5922A61K2300/00
Inventor 张琳
Owner 泰投华信(北京)科技发展有限公司
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