Application of nucleotide mixture in preparing preparations for preventing or alleviating senile sarcopenia

A technology of nucleotides and mixtures, which is applied in the field of preparation of preparations for preventing or alleviating senile sarcopenia, and can solve the problems that exogenous nucleotides have not been reported.
CN113398144BActive Publication Date: 2022-04-01ι™ˆηŽ‰ζΎ
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Patent Information

Authority / Receiving Office
CN Β· China
Patent Type
Patents(China)
Current Assignee / Owner
ι™ˆηŽ‰ζΎ
Publication Date
2022-04-01

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Abstract

The invention discloses the application of a nucleotide mixture in preparing preparations for preventing or alleviating senile sarcopenia, and belongs to the field of medicine and health care. The nucleotide mixture is composed of five 5'-mononucleotides or their sodium salt forms, and the mass ratios of various nucleotides converted into CMP, AMP, UMP, GMP, and IMP acid forms are: CMP23-78 %, AMP6-44%, UMP7-40%, GMP7-51%, IMP is 0, or greater than 0 and not higher than 2.5%. Nucleotides have a small molecular weight, can be absorbed by the human body quickly and have high bioavailability. The present invention finds that the intake of nucleotides can improve the skeletal muscle function of the aged body and increase the muscle mass by improving mitochondrial dysfunction and reducing oxidative stress, thereby preventing and treating sarcopenia. A new approach is provided for preparing medicine or functional food for preventing and treating sarcopenia.
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Description

technical field

[0001] The invention belongs to the field of medicine and health care, and relates to a nucleotide product and its new application, in particular to the application of a nucleotide mixture produced by enzymatic degradation using ribonucleic acid as a raw material in the preparation of preparations for preventing or alleviating senile sarcopenia. Background technique

[0002] In today's society, with the obvious decline of fertility rate, the increase of life expectancy is leading to the rapid aging of the global population. According to data released by the National Bureau of Statistics, by the end of 2019, the number of elderly people aged 60 and over in China reached 254 million, accounting for 18.1% of the total population, and the number of elderly people aged 65 and over reached 176 million, accounting for 12.6% of the total population. The report predicts that China will enter an aging society from an aging society around 2022, when the population aged ...

Claims

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