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Dandelion extract as well as preparation method and application thereof

A technology of dandelion extract and dandelion, which is applied in the direction of medical formula, drug combination, plant raw materials, etc., to achieve the effect of saving production cost, saving cost and simple process

Inactive Publication Date: 2021-09-24
INST OF BASIC THEORY OF TCM CHINA ACADEMY OF CHINESE MEDICAL SCI +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is no research on macromolecular active ingredients in dandelion in this field

Method used

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  • Dandelion extract as well as preparation method and application thereof
  • Dandelion extract as well as preparation method and application thereof
  • Dandelion extract as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Example 1 Comparison of extract efficacy and chemical component content prepared by different extraction methods of dandelion

[0035] 1. Materials

[0036] 1.1 Experimental drugs

[0037] Homogenization of fresh herbs: take 20g of fresh dandelion, add a small amount of water to grind it several times, combine the grinding solution, and dilute to 40mL;

[0038] Fresh medicinal water extract: Take 20g of fresh dandelion, add 6 times the amount of water to reflux to extract twice, each time for 30min, combine the decoction, and concentrate to 40mL;

[0039] Dry medicinal water extract: Take 20g of dried dandelion, add 6 times the amount of water to reflux to extract twice, each time for 30min, combine the decoction, and concentrate to 40mL;

[0040] Positive control drug: Aspirin enteric-coated tablets, purchased from Shineway Pharmaceutical Co., Ltd., batch number 1004172, ground and prepared into a 15 mg / mL solution with distilled water.

[0041] 1.2 Experimental ani...

Embodiment 2

[0090] Take 20g of fresh dandelion, add appropriate amount of water, squeeze the juice with a juicer, and filter to obtain the homogenate of dandelion fresh medicine.

[0091] Measure its protein and polysaccharide content according to the method of embodiment 1 and be respectively: protein: 0.62%, polysaccharide 5.8%.

Embodiment 3

[0093] Take 20g of fresh dandelion, crush it with liquid nitrogen, add an appropriate amount of water, extract the juice with a juicer, and filter to obtain a homogenate of dandelion fresh medicine.

[0094] Measure its protein and polysaccharide content according to the method of embodiment 1 and be respectively: protein: 0.75%, polysaccharide 6.4%.

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Abstract

The invention provides a dandelion extract as well as a preparation method and application thereof. The dandelion extract is prepared by the following steps: taking fresh dandelion, adding water, squeezing, and filtering to obtain the dandelion extract; wherein the dandelion extract comprises the following components in percentage by weight: 4%-10% of polysaccharide and 0.3%-1% of protein. The dandelion extract disclosed by the invention is rich in macromolecular substances such as polysaccharide, protein and the like, and extremely low in content of small molecular substances such as phenolic acid, flavone, phenylpropanoid and the like, so that the dandelion extract has remarkable antioxidant and anti-inflammatory activity.

Description

technical field [0001] The application relates to a dandelion extract and its preparation method and application, belonging to the field of food health products. Background technique [0002] Dandelion (Latin scientific name: Taraxacum mongolicum Hand-Mazz.) is a perennial herb of the family Asteraceae. Root cone-shaped, surface brown, shriveled, leaf edge sometimes with wavy teeth or pinnately parted, base gradually narrowed into petiole, petiole and main vein are often reddish-purple, upper part of scape purple-red, densely covered with spider-like white Villous hair: inflorescence head, involucre bell-shaped, achene dark brown, long pappus white, flower and fruit period from April to October. Bitter, sweet, cold, return liver, stomach meridian, have heat-clearing and toxic substances removing, reduce swelling and dissipate stagnation, diuretic effect of treating stranguria. Many studies have shown that dandelion has broad-spectrum antibacterial effects, anti-gastric dam...

Claims

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Application Information

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IPC IPC(8): A61K36/288A61P39/06A61P29/00
CPCA61K36/288A61P39/06A61P29/00A61K2236/31A61K2236/53
Inventor 柏冬吴晓霞李宏强朱慧
Owner INST OF BASIC THEORY OF TCM CHINA ACADEMY OF CHINESE MEDICAL SCI
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