Composition for preventing hair loss or promoting hair growth, comprising, as active ingredient, mixed extract of cucumber, eggplant and snail

A technology of cucumber extract and snail extract, which is applied in the field of compositions containing a mixture of cucumber, eggplant and snail extract as active ingredients for preventing hair loss or promoting hair growth, can solve side effects such as dermatitis and other problems, and achieve Improve the effect of hair loss

Active Publication Date: 2021-09-24
李东琓 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, hair loss will occur again after drug withdrawal, and it is reported that long-term use can cause side effects such as dermatitis (Kaufman K.D. (1996), Elsevier Science, pp.363-365)

Method used

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  • Composition for preventing hair loss or promoting hair growth, comprising, as active ingredient, mixed extract of cucumber, eggplant and snail
  • Composition for preventing hair loss or promoting hair growth, comprising, as active ingredient, mixed extract of cucumber, eggplant and snail
  • Composition for preventing hair loss or promoting hair growth, comprising, as active ingredient, mixed extract of cucumber, eggplant and snail

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1-1

[0111] Example 1-1: Preparation of extract of cucumber, eggplant and snail mixture

[0112] Dried cucumbers are obtained by washing fresh cucumbers, removing the top and bottom ends of about 2 cm, halving vertically, removing the cucumber seeds and then drying them, and dried eggplants are obtained by removing the eggplant stems and then drying them, by cutting Snails were steamed for 10 minutes, gutted and then dried to obtain dried snails, after mixing dry cucumber, dried eggplant, and dried snails at a weight ratio of 4:2:1 and adding 10 weight equivalents of water, extraction was performed at 90°C for 10 hours , and the extract was filtered under reduced pressure. The filtrate was concentrated using a vacuum evaporator, and then freeze-dried to prepare extracts of cucumber, eggplant, and snail.

Embodiment 1-2

[0113] Example 1-2: Preparation of a mixture of cucumber extract, eggplant extract and snail extract

[0114] Wash fresh cucumbers and remove about 2 cm of tops and bottoms. Cut fresh cucumbers in half vertically and remove seeds. After adding 5 weight equivalents of water, extraction was performed at 90° C. for 10 hours, and then the extract was filtered under reduced pressure. The filtrate was concentrated using a vacuum evaporator, and then freeze-dried to prepare cucumber extract.

[0115] Dried eggplant was obtained by removing the eggplant stem and then drying, and after adding 5 weight equivalents of water, extracted at 90° C. for 10 hours. After filtering under reduced pressure, the filtrate was concentrated using a vacuum evaporator, and then freeze-dried to prepare eggplant extract.

[0116] After the snails were steamed for 10 minutes and guts were removed, extraction was performed at 90° C. for 10 hours after adding 10 weight equivalents of water. After filte...

Embodiment 1-3

[0118] Example 1-3: Preparation of a mixture of cucumber extract, eggplant extract and snail extract

[0119] A mixture of cucumber, eggplant and snail extracts was prepared by mixing the cucumber extracts, eggplant extracts and snail extracts of Examples 1-2 in a weight ratio of 2:2:1.

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PUM

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Abstract

The present invention relates to a composition for preventing hair loss or promoting hair growth, comprising, as an active ingredient, a mixed extract of cucumber, eggplant and snail. The composition according to the present invention comprises, as an active ingredient, a mixed extract of cucumber, eggplant and snail so as to increase the expression of hepatocyte growth factor (HGF), keratinocyte growth factor (KGF) and insulin-like growth factor (IGF-1) in dermal papilla cells, which are known to play a vital role in inducing new pores and maintaining hair growth, exhibits an effect on hair growth equivalent to that of minoxidil in a test for confirming the effect on hair growth, performed after removing hair from 6-week-old C57BL / 6 mice, and is confirmed to have a hair loss alleviation effect in a human clinical trial, and thus the present invention can be effectively used as cosmetic composition and a pharmaceutical composition for external application to the skin.

Description

technical field [0001] The present disclosure relates to a composition comprising a mixture of cucumber extract, eggplant extract and snail extract as an active ingredient for preventing hair loss or promoting hair growth, particularly a cosmetic composition and a skin external use pharmaceutical composition. Background technique [0002] Hair is one of the appendages of the skin. It is morphologically derived from the epithelium and forms at 2 months of age. Hair is divided into fine vellus hairs and coarse terminal hairs according to its thickness. Hair grows in a specific cycle and does not fall out immediately. Every hair follicle goes through active and resting phases. During the anagen phase, the anagen phase, the cells in the hair bulb grow actively, resulting in hair growth. In human hair, 85% of the hair follicles are in the anagen phase for 3 to 6 years, 5% are in the anagen phase for 2 to 3 weeks, in which the hair follicles begin to shrink, and the remaining...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/81A61K36/9068A61K8/9794A61K8/9761A61K8/9789A23L33/105A61P17/14A61Q7/00A61K35/618
CPCA61K36/42A61K36/81A61K35/618A61K36/14A61K36/804A61K36/9068A61K36/232A61K36/28A61K36/27A61K36/899A61K8/9789A61K8/9761A61K8/9794A61K9/0014A61P17/14A61Q7/00A23L33/105A61K2800/5922A23V2002/00A61K2300/00A23V2200/318A23V2250/204A23V2250/21A61K8/9783A61K8/9767A61K36/489A61K36/537A61K36/882A61K8/98A61Q5/002
Inventor 李东琓金成玉李河燮
Owner 李东琓
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