Control method, system and equipment of super-resolution ion mobility spectrometer

An ion mobility spectrometer and super-resolution technology, applied in the control field of super-resolution ion mobility spectrometer, can solve the problem that the migration time cannot further improve the resolution of the instrument, and achieve the effect of breaking the resolution limit and eliminating the influence

Pending Publication Date: 2021-10-01
XIDIAN UNIV
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Problems solved by technology

Even if the existing migration time is increased on the basis of the resolution limit, the resolution of the instrument cannot be further improved.

Method used

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  • Control method, system and equipment of super-resolution ion mobility spectrometer
  • Control method, system and equipment of super-resolution ion mobility spectrometer
  • Control method, system and equipment of super-resolution ion mobility spectrometer

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Embodiment Construction

[0057] In order to make the object, technical solution and advantages of the present invention more clear, the present invention will be further described in detail below in conjunction with the examples. It should be understood that the specific embodiments described here are only used to explain the present invention, not to limit the present invention.

[0058] Aiming at the problems existing in the prior art, the present invention provides a control method, system and equipment of a super-resolution ion mobility spectrometer. The present invention will be described in detail below with reference to the accompanying drawings.

[0059] like figure 1 As shown, the control method of the super-resolution ion mobility spectrometer provided by the embodiment of the present invention includes the following steps:

[0060] S101, the ion gate is normally closed and opened briefly to obtain an ion spectrum with a peak higher than the baseline;

[0061] S102, the ion gate is normall...

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Abstract

The invention belongs to the technical field of analytical chemistry and analytical instruments, and discloses a control method, system and equipment of a super-resolution ion mobility spectrometer. The control method of the super-resolution ion mobility spectrometer comprises the steps that an ion gate is normally closed and temporarily opened to obtain an ion spectrogram with a spectral peak higher than a baseline; the ion gate is normally opened and temporarily closed to obtain an ion spectrogram with a spectral peak lower than the baseline; and the ion spectrogram with the spectral peak higher than the baseline is subtracted from the ion spectrogram with the spectral peak lower than the baseline to obtain a super-resolution ion spectrogram. According to the invention, a super-resolution implementation method in optical imaging is used for reference, and the control method of the super-resolution ion mobility spectrometer is provided by changing a sample injection mode and processing data, so that the influence of a diffusion phenomenon and coulomb repulsive force between ions on the resolution of the ion mobility spectrometer can be reduced or even eliminated, and the resolution limit of the ion mobility spectrometer when the migration tube distance is fixed is broken through.

Description

technical field [0001] The invention belongs to the technical field of analytical chemistry and analytical instruments, and in particular relates to a control method, system and equipment of a super-resolution ion mobility spectrometer. Background technique [0002] At present, ion mobility spectrometry is an analytical instrument that uses ion mobility to separate different sample components. Compared with large analytical instruments such as traditional mass spectrometry, it has technical advantages such as low cost, miniaturization, fast detection speed, and high sensitivity. It is widely used in various fields such as security inspection, analysis, and medical treatment. [0003] The detection process of ion mobility spectrometry can be divided into three stages: ionization, migration, and detection. The migration stage is the main stage for separating different component ions, which is jointly completed by the ion gate and the migration tube. At the beginning of the mi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N27/622
CPCG01N27/622
Inventor 郭开泰梁继民郑洋胡海虹任胜寒林峰
Owner XIDIAN UNIV
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