Biosensor and preparation method thereof

Abstract

The invention provides a biosensor and a preparation method thereof, and the biosensor comprises an electrode structure which comprises a substrate, a first conductive layer, a first insulating layer, a second conductive layer, a third conductive layer and a second insulating layer, wherein the first conductive layer is formed on the substrate; the first insulating layer is formed on the first conducting layer, and a part of area of the first conducting layer is exposed to form a working electrode; the second conductive layer is formed on the first insulating layer; the third conductive layer is formed on a partial region of the second conductive layer; the second insulating layer is at least formed on the second conducting layer, a part of area of the second conducting layer is exposed to form a counter electrode, and at least a part of area of the third conducting layer is exposed to form a reference electrode; and the reaction film layer is formed on the working electrode and is used for carrying out electrochemical reaction with a target object. The biosensor is simple and reasonable in structure and beneficial to batch production.

Description

technical field [0001] The invention relates to the technical field of medical devices, in particular to a biosensor and a preparation method thereof. Background technique [0002] The definition of a biosensor is "a device that uses immobilized biomolecular binding transducers to detect environmental chemicals inside or outside the organism or interact specifically with them to generate a response." According to the differences of living substances used in the sensors, biosensors can be divided into tissue sensors, cell sensors, enzyme sensors, etc. , insulin sensors, etc., and biosensors can also be divided into immune sensors, drug sensors, etc. according to their uses. So far, the most commercially successful biosensor is the glucose sensor, which is used to monitor glucose in body fluids such as human blood, interstitial fluid, and sweat. Due to the huge population of diabetic patients worldwide, glucose sensors have a huge market share. [0003] Glucose monitoring re...

AI Technical Summary

Problems solved by technology

Among them, the in vitro sensor monitors the blood glucose data of a single point through fingertip blood collection. The fully implanted sensor has biocompatibility problems, and the surgical implantation and removal are more complicated. The subcutaneous implanted sensor is quickly implanted in a minimally invasive way. In or out, also capable of continuous glucose monitoring

However, the subcutaneous implantable glucose sensor in the prior art has problems such as complex preparation process, high cost, short life, poor anti-interference ability, and sensitivity attenuation.

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