Method for recognizing antioxidant protein based on interaction of amino acid composition and protein

Abstract

The invention discloses a method for recognizing antioxidant protein based on amino acid composition and protein interaction and relates to the technical field of medicine. Aiming at solving the problem that in the prior art, when a secondary structure is predicted according to sequence information and features of protein secondary structure information are extracted through tools such as PSI-PRED, errors exist in the predicted protein secondary structure, and then the accuracy of antioxidant protein recognition is low, the invention proposes a brand-new antioxidant protein recognition method: the characteristics of the antioxidant protein sequence are expressed through the protein-protein interaction characteristics and the amino acid composition, so the accurate recognition of the antioxidant protein can be achieved, and a theoretical basis is provided for corresponding protein positioning, disease analysis and drug research. According to the method, multiple unbalanced data processing methods are introduced when unbalanced antioxidant protein data are processed, finally, the model obtained by processing the data through the SMOTE algorithm is optimal, and the recognition effect of the antioxidant protein is optimized.

Description

technical field [0001] The invention relates to the field of medical technology, in particular to a method for identifying antioxidant proteins based on amino acid composition and protein interaction. Background technique [0002] Reactive oxygen species (ROS) are products of metabolic processes. Excessive ROS concentration will generate too many oxygen free radicals, and the antioxidant system in the organism cannot eliminate ROS fast enough, resulting in oxidative stress. Excessive oxidative stress can affect the destruction of macromolecular structures and even lead to cell death, which leads to aging and triggers genetic diseases such as cancer, acute and chronic kidney disease, neurodegenerative diseases, cardiovascular diseases, diabetes and atherosclerosis hardening. Antioxidant proteins can balance this oxidative stress response and prevent excessive concentrations of ROS from causing cell damage. However, traditional methods for identifying antioxidant proteins, ...

AI Technical Summary

Problems solved by technology

[0003] The purpose of the present invention is: for the secondary structure predicted according to sequence information in the prior art, when using tools such as PSI-PRED to extract the characteristics of protein secondary structure information, there are errors in the predicted protein secondary structure, which in turn leads to Identify the problem of low accuracy and propose a method to identify antioxidant proteins based on amino acid composition and protein interaction

Images