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Locally-enhanced textile-based valve leaflet for artificial heart valve and application of valve leaflet

An artificial heart valve, local enhancement technology, applied in the direction of heart valve, textile, textile and paper making, etc., can solve the problem of complex manufacturing process, achieve the enhancement of local tightness and/or thickness, improve mechanical properties, improve tear resistance effect of ability

Active Publication Date: 2021-12-10
DONGHUA UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But generally speaking, this kind of composite material has the hidden danger of delamination due to the problem of interface fastness in the environment of high-cycle bending stress, and the manufacturing process is relatively complicated.

Method used

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  • Locally-enhanced textile-based valve leaflet for artificial heart valve and application of valve leaflet
  • Locally-enhanced textile-based valve leaflet for artificial heart valve and application of valve leaflet
  • Locally-enhanced textile-based valve leaflet for artificial heart valve and application of valve leaflet

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0079] A valve leaflet for a locally reinforced textile-based artificial heart valve, comprising such as figure 2 The several special regions shown are free edge 1, junction 2, abdomen 3 and attachment edge 4. The preparation method of the leaflet is as follows:

[0080] (1) Pattern design and tissue filling: store the leaflet graphics designed in the CAD jacquard design system; divide the leaflet graphics into different areas (local area and non-local area, wherein the local area includes the target area and the transition area, the transition area surround the target area, and both have the same contour shape). Each color represents a weave, and the corresponding fabric weave can be selected by filling different areas with different colors. In this example, the local area is the attachment edge area, and the area of ​​the local area is 1.20 times that of the target area, such as Figure 6 Shown; The form of local enhancement is that the tightness of the local area is gre...

Embodiment 2

[0088] A valve leaflet for a partially reinforced textile-based artificial heart valve, comprising an attachment edge, an abdomen, a joint and a free edge; its preparation method is as follows:

[0089] (1) Pattern design and tissue filling: store the leaflet graphics designed in the CAD jacquard design system, and divide it into different areas (local area and non-local area, wherein the local area includes the target area and transition area, and the transition area surrounds target area, and the outline shape of the two is the same). Each color represents a weave, and the corresponding fabric weave can be selected by filling different areas with different colors. In this example, the local area is the junction area, and the area of ​​the local area is 1.67 times that of the target area, such as Figure 7 As shown; the form of local enhancement is that the thickness of the local area is greater than that of the non-local area, that is: thickness control, wherein the non-loc...

Embodiment 3a

[0096] A valve leaflet for a partially reinforced textile-based artificial heart valve, comprising an attachment edge, an abdomen, a joint and a free edge; its preparation method is as follows:

[0097](1) Pattern design and tissue filling: store the designed leaflet graphics in the CAD jacquard design system, and divide them into different regions (local regions and non-local regions). Each color represents a weave, and the corresponding fabric weave can be selected by filling different areas with different colors. In this example, the local area is the entire free edge area; the form of local enhancement is that the tightness of the local area is greater than that of the non-local area, that is, tightness control. The non-local area is plain weave; the local area is diamond-shaped twill weave.

[0098] (2) Setting the weaving parameters: the non-local area and the local area share the warp and weft yarns of the same system; the warp and weft yarns are both 40D mulberry silk...

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Abstract

The invention relates to a locally-enhanced textile-based valve leaflet for an artificial heart valve and application of the valve leaflet. The valve leaflet comprises an attachment edge, an abdomen, a joint and a free edge; the valve leaflet is a woven jacquard fabric which is formed at one time; the local enhancement means that the tightness and / or thickness of a local area on the valve leaflet are / is greater than those of a non-local area on the valve leaflet; the local area comprises one or more of an attachment edge area, a joint area, a free edge area and an abdomen part area; and the abdomen part area refers to a plurality of line-shaped areas distributed in the abdomen area by taking the radial center line of the valve leaflet as a symmetry axis. According to the locally-enhanced textile-based valve leaflet for the artificial heart valve, integrated forming and multi-dimensional arbitrary regulation and control can be achieved, the tear resistance and hemodynamic performance of the valve leaflet are improved, the stress concentration phenomenon is reduced, and the long-term durability is improved.

Description

technical field [0001] The invention belongs to the technical field of heart valves, and relates to a partially reinforced textile-based artificial heart valve leaflet and an application thereof. Background technique [0002] In my country, the incidence rate of valvular heart disease is 2.5-3.2%, and there are about 4 million patients. More than 200,000 patients need valvular surgery every year, and it currently occupies the first place in adult heart surgery. When the heart valve is damaged to a certain extent, it cannot be repaired by surgery, and artificial heart valve replacement is mainly used to restore or improve the function of the valve. At present, artificial heart valves widely used clinically include mechanical valves and biological valves, but mechanical valves are prone to infection and thrombosis, and patients need to take anticoagulant drugs for life. Biological valves are mostly designed as symmetrical, uniform-thickness trilobate valves, which provide a g...

Claims

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Application Information

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IPC IPC(8): A61F2/24D03D15/283
CPCA61F2/2412A61F2/2415A61F2/2463D03D15/283A61F2240/002D10B2331/04D10B2321/021
Inventor 王璐陈诗萍李超婧毛吉富林婧王富军
Owner DONGHUA UNIV
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