Microneedle pouring system and microneedle preparation method

Abstract

The invention discloses a microneedle pouring system and a microneedle preparation method. The microneedle pouring system comprises a vacuum chamber, a motion platform, a first motion assembly, a liquid filling needle assembly, a second motion assembly and a controller, wherein the motion platform is arranged in the vacuum chamber; the first motion assembly comprises a first transmission part and a first driving part which are connected with each other, the motion platform is connected with the first transmission part, and the first transmission part is driven by the first driving part to drive the motion platform to move in the first direction or / and the third direction; the liquid filling needle assembly comprises a liquid outlet head and a liquid filling needle rod, and one end of the liquid filling needle rod extends into the vacuum chamber and is connected with the liquid outlet head; the second motion assembly comprises a second transmission part and a second driving part which are connected with each other, the liquid filling needle is connected with the second transmission part, and the second transmission part is driven by the second driving part to drive the liquid filling needle to move in the second direction; and the first driving part or / and the second driving part is / are in communication connection with the controller. Uniform pouring of a large-plane microneedle pouring mold can be rapidly completed.

Description

technical field [0001] The invention relates to the technical field of microneedles, in particular to a microneedle pouring system and a microneedle preparation method. Background technique [0002] Micromolding is a high-precision micro-nano manufacturing technology that uses micro-replication molds to shape microstructures. This technology has the advantages of high replication accuracy, low cost, and small residual stress, and is widely used in the preparation of micro-nano structures such as micro-gears, micro-needles, micro-fluidic chips, and light guide plates in various fields such as machinery, medicine, and biology. . The most critical step in micromolding is mold filling, which is to fill the cavity of the mold with a high filling ratio of the replication liquid material, which is a key factor affecting the accuracy of microstructure replication. [0003] Commonly used mold filling methods mainly include pressure filling, centrifugal filling and vacuum filling. ...

AI Technical Summary

Problems solved by technology

This method has special requirements for mold making materials. At the same time, when the vacuumed mold is poured under normal pressure, when the gas inside the mold is sucked back, it is difficult to ensure quantifiable consistency between different parts of the same mold and different molds.

The whole pouring process, including the vacuum exhausting of the mold in the early stage and the gas sucking back into the needle body after filling, takes a relatively long time, which is not conducive to mass production

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