Composition containing silybum marianum extract and postbiotics and application of composition in liver protection

A technology of extract and milk thistle, applied in the field of composition, can solve the problem of liver inflammation unable to play a protective role and so on

Inactive Publication Date: 2021-12-28
南京北极光生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For sub-healthy people, simple supplementation of antibacterial, anti-inflammatory and antioxidant supplements such as milk thistle can only reduce the inflammation that is already occurring, and cannot protect the liver inflammation caused by external invasion of lipopolysaccharides, etc.

Method used

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  • Composition containing silybum marianum extract and postbiotics and application of composition in liver protection
  • Composition containing silybum marianum extract and postbiotics and application of composition in liver protection
  • Composition containing silybum marianum extract and postbiotics and application of composition in liver protection

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0039] A composition comprising milk thistle extract and inactivated Lactobacillus plantarum L137, silybin (including silybin A and silybin B) in the milk thistle extract accounts for 80% of milk thistle extract is in the form of milk thistle-phospholipid complex, milk thistle extract is 40% (w / w), and inactivated Lactobacillus plantarum L137 is 60% (w / w).

Embodiment 2

[0041] A composition containing milk thistle extract and inactivated Lactobacillus plantarum L137, in the milk thistle extract, silybin accounts for 70% of the milk thistle extract, and the milk thistle extract is 20% (w / w), the inactivated Lactobacillus plantarum L137 was 80% (w / w).

Embodiment 3

[0043] A composition containing milk thistle extract and inactivated Lactobacillus plantarum L137 and live Lactobacillus plantarum, silybin in milk thistle extract accounts for 90% of milk thistle extract, milk thistle extract Plantarum was 33.3% (w / w), and Lactobacillus plantarum was 66.7% (w / w).

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Abstract

The invention discloses a composition. The composition contains a silybum marianum extract and postbiotics; and the silybum marianum extract can be in the form of a silybum marianum extract microcapsule, inactivated lactobacillus plantarum L137 can be selected as the postbiotics, the postbiotics can regulate intestinal flora balance, repair intestinal tracts, reduce intestinal leakage and reduce the cause of hepatitis, and the combination of the silybum marianum extract and the postbiotics has the effect of reducing liver injury.

Description

technical field [0001] The invention relates to a composition, in particular to a composition for reducing liver damage and its application. Background technique [0002] Milk thistle, also known as milk thistle, is native to the Mediterranean region. It has been used as a medicinal plant for nearly two thousand years, and it is still widely used as a very effective liver protection plant. It can help detoxify the liver and can also be used to manage chronic liver disease. Milk thistle can activate the regeneration of liver proteins, restore the activity of liver cells damaged by alcohol and viruses, remove free radicals, maintain the permeability of liver cell membranes, reduce the damage of toxins to the liver, and protect the liver and liver from long-term drinking. People with acute and chronic hepatitis, fatty liver, cirrhosis and toxic liver damage. [0003] Milk thistle extract uses the dried fruit of Silybum marianum as raw material, and commercial extracts are usu...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/28A61K31/357A61K31/352A61K35/747A61P1/16A61P39/00A61P25/24A61P25/22A23L33/105A23L33/135A23L33/18A23L2/52A23L2/39
CPCA61K36/28A61K31/357A61K31/352A61K35/747A61P1/16A61P39/00A61P25/24A61P25/22A23L33/105A23L33/135A23L33/18A23L2/52A23L2/39A23V2002/00A23V2400/169A61K2300/00A23V2200/30A23V2250/21A23V2250/55
Inventor 丁峰李靖
Owner 南京北极光生物科技有限公司
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