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Traditional Chinese medicine composition for treating asthma, preparation method and application thereof

The technology of a composition and a traditional Chinese medicine is applied in the field of traditional Chinese medicine composition for treating asthma and its preparation field, which can solve the problems of lingering patient's condition, decreased body resistance and the like, and achieve the effect of good therapeutic effect.

Inactive Publication Date: 2022-02-08
GUANGDONG HOSPITAL OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there are still some patients whose condition is lingering and unhealed for a long time. There are a certain proportion of CVA patients who have repeated illnesses due to mistreatment, or the body’s resistance is reduced due to the abuse of antibiotics, or due to insufficient congenital endowment. In the initial stage of the disease, the lung qi is deficient, and the kidneys are affected over time. The kidney qi is not satisfied, and the evil qi is induced, which gradually leads to the deficiency of both the lung and the kidney.

Method used

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  • Traditional Chinese medicine composition for treating asthma, preparation method and application thereof
  • Traditional Chinese medicine composition for treating asthma, preparation method and application thereof
  • Traditional Chinese medicine composition for treating asthma, preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] Raw materials: Astragalus 15g, Agrimony 15g, Morinda officinalis 10g, Ephedra 5g, Asarum 3g, Fangfeng 10g, Pinellia 10g, Schisandra 5g, Bupleurum 10g, Scutellaria baicalensis 10g.

[0030] Preparation:

[0031] After weighing the above components, soak the above components in water for 30 minutes (the water temperature does not exceed 60°C). When soaking, ensure that the liquid level is 2 cm higher than the surface of the above drug; after the drug soaks and becomes soft, decoct for 30 minutes for the first time , cover the pot well to reduce evaporation, filter out the medicinal liquid after decoction, and obtain decoction 1; continue to add new water to the remaining medicine for the second decoction, decoct for 20 minutes, pour out the soup, and obtain decoction 2; Combine decoction 1 and decoction 2 to get the product; total decoction volume: 400-600ml per dose for adults, 100-300ml per dose for children.

Embodiment 2

[0033] Raw materials: Astragalus 10g, Agrimony 10g, Morinda officinalis 5g, Ephedra 5g, Asarum 2g, Fangfeng 10g, Pinellia 5g, Schisandra 5g, Bupleurum 5g, Scutellaria baicalensis 5g.

[0034] The preparation method is the same as in Example 1.

Embodiment 3

[0036] Raw materials: Astragalus 25g, Agrimony 25g, Morinda officinalis 15g, Ephedra 10g, Asarum 5g, Fangfeng 15g, Pinellia 15g, Schisandra 10g, Bupleurum 15g, Scutellaria baicalensis 15g.

[0037] The preparation method is the same as in Example 1.

[0038] 2. Clinical trial data

[0039] 1. General Information

[0040]A total of 102 CVA patients who were treated in the respiratory specialist clinics of the General Hospital of Guangdong Provincial Hospital of Traditional Chinese Medicine and its branches from July 2016 to July 2018 were selected, and 102 qualified subjects were randomly divided into two groups by using the random number table method. That is, the treatment group and the control group, 52 cases in the treatment group and 50 cases in the control group. Among them, there was 1 case in the control group who did not take the test drug after inclusion, and it was treated as an excluded case, that is, 101 cases in the full analysis set (FAS), including 52 cases in...

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Abstract

The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating asthma, a preparation method and application thereof, and the traditional Chinese medicine composition is prepared from the following traditional Chinese medicine components: astragalus membranaceus, hairyvein agrimony, morinda officinalis, roasted ephedra, asarum, divaricate saposhnikovia root, rhizoma pinellinae praeparata, schisandra chinensis, radix bupleuri and scutellaria baicalensis. The traditional Chinese medicine composition can effectively relieve cough symptoms of CVA patients, has good curative effects on improving traditional Chinese medicine syndromes, improving life quality, improving lung function PEF and improving the remission rate, has obvious advantages on reducing relapse, has few adverse reactions, is good in safety, verifies the effectiveness of warming lung, tonifying kidney, dispelling wind and reducing phlegm, and has good market prospects.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating asthma, a preparation method and application thereof. Background technique [0002] Cough variant asthma (Cough variant asthma, CVA) is a special type of asthma with cough as the only or main clinical manifestation, without obvious symptoms or signs such as wheezing and shortness of breath, but with airway hyperresponsiveness. The results of a multi-center prospective survey of chronic cough in China showed that: CVA is one of the most common causes of chronic cough, accounting for about 1 / 3 of the causes of chronic cough. Because of its non-specific clinical symptoms, it is very easy to be misdiagnosed and missed diagnosis, which leads to the inability to timely and standardize the medication and cause the disease to be mistreated. The cough is protracted, and some patients may develop into typical ast...

Claims

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Application Information

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IPC IPC(8): A61K36/8888A61P11/06
CPCA61K36/481A61K36/73A61K36/746A61K36/17A61K36/268A61K36/238A61K36/8888A61K36/79A61K36/57A61K36/233A61K36/539A61K9/0095A61P11/06A61K2236/331A61K2236/39A61K2236/53A61K2236/51A61K2300/00
Inventor 林琳吴蕾陈远彬范龙于旭华范斐婷肖晶旻梁紫尧
Owner GUANGDONG HOSPITAL OF TRADITIONAL CHINESE MEDICINE