Traditional Chinese medicine composition for treating blood stasis type bone arthralgia, preparation and application

A technology for blocking blood stasis and composition, applied in the field of traditional Chinese medicine compositions and preparations, and can solve problems such as medical resource consumption and the like

Active Publication Date: 2022-04-05
云南省中医医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, non-steroidal anti-inflammatory drugs are accompanied by huge gastrointestinal reactions and the risk of cardiovascular disease, and surgical treatment will also bring huge consumption of medical resources

Method used

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  • Traditional Chinese medicine composition for treating blood stasis type bone arthralgia, preparation and application
  • Traditional Chinese medicine composition for treating blood stasis type bone arthralgia, preparation and application
  • Traditional Chinese medicine composition for treating blood stasis type bone arthralgia, preparation and application

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032]Angelica 12g, Salvia 10g, Safflower 15g, Guizhi 12g, Scorpion 10g, Earthworm 12g, Centipede 6g, Duhuo 15g, Notopterygium 12g, Atractylodes 9g, Asarum 9g, Licorice 9g. Put all the medicines in the pot according to the prescription, add water to cover the medicines by 2~3cm, soak for 30 minutes, first boil on high heat, then fry on low heat for 30 minutes, and take about 150ml of juice; add appropriate amount of water again, boil on high heat, Fry for 10 minutes, take about 150ml of juice, and combine the soup to get a decoction.

Embodiment 2

[0034] Prescription: Angelica 18g, Danshen 15g, Safflower 10g, Guizhi 9g, Scorpion 5g, Dilong 24g, Centipede 3g, Duhuo 24g, Notopterygium 24g, Atractylodes 20g, Asarum 6g, Licorice 6g. Decoct each herbal flavor of the prescription with water at a weight ratio of 1:6, add water and decoct 1 to 3 times, each time for 30 minutes, and combine the decoction liquid; condense the obtained decoction liquid at 70°C and vacuum at -0.02~-0.06MPa to thicken Paste, the thick paste has a density of 1.20g / ml at 50°C; the thick paste is dried at 70°C under a vacuum of -0.02~-0.06MPa to form a dry paste, and the dry paste is crushed and passed through a 100-mesh sieve to obtain a mixed dry paste powder. Mix 15g of dextrin evenly, add an appropriate amount of 70% ethanol, wet granulate, and obtain granules after drying.

Embodiment 3

[0036] Prescription: Angelica 9g, Salvia miltiorrhiza 20g, Safflower 20g, Guizhi 18g, Scorpion 15g, Dilong 18g, Centipede 12g, Duhuo 12g, Notopterygium 18g, Atractylodes 15g, Asarum 12g, Licorice 18g. Weigh each herb in the formula according to the formula, add water to decoct 1 to 3 times according to the weight ratio of medicine to water 1:8, each time for 60 minutes, and combine the decoction; Concentrate into a thick paste under vacuum of -0.06MPa, and the density of the thick paste is 1.35g / ml at 60°C; dry the thick paste at 65°C under a vacuum of -0.02~-0.06MPa to form a dry paste, crush the dry paste and pass through 100 Mesh sieve to obtain mixed dry cream powder, and pan pills with 30% ethanol to obtain pills.

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Abstract

The invention discloses a traditional Chinese medicine composition for treating blood stasis type bone arthralgia, a preparation and application, the traditional Chinese medicine composition comprises the following components by weight: 10-20 g of Chinese angelica, 9-18 g of safflower, 9-18 g of cassia twig, 12-24 g of radix angelicae pubescentis, 12-24 g of notopterygium root, 9-18 g of rhizoma atractylodis, 6-12 g of asarum, 6-15 g of scorpion, 3-12 g of centipede, 10-20 g of salvia miltiorrhiza, 12-24 g of earthworm and 6-18 g of liquorice, and the traditional Chinese medicine composition is suitable for treating blood stasis type bone arthralgia. The traditional Chinese medicine is caused by wind-cold-dampness pathogen obstructed in meridians and collaterals, unhealed for a long time, qi stagnation and blood stasis, meridian obstruction and malnutrition of muscles and bones. The whole formula is mainly used for promoting blood circulation to remove meridian obstruction and also has the effects of dispelling wind and eliminating dampness. The traditional Chinese medicine has the effects of treating both symptoms and root causes, combining purgation and tonification, strengthening body resistance and eliminating evil, and does not forget to tonify liver and kidney, strengthen tendons and bones, activate blood and enrich blood when being used for promoting blood circulation to remove blood stasis, expelling wind-damp, activating meridians and relieving pain; and the body resistance is not hurt. According to the traditional Chinese medicine composition, the total effective rate of the traditional Chinese medicine syndrome curative effect is 89.1%, the total effective rate of a control group is only 75.9%, and the curative effect of the traditional Chinese medicine composition on the aspect of treating the blood deficiency and blood stasis type cervical spondylosis is remarkably superior to that of a control group etoricoxib tablet.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine compositions and preparations, and in particular relates to a traditional Chinese medicine composition, preparation and application for treating blood stagnation type osteoarthritis. Background technique [0002] Arthralgia, as a common and unique disease, has been recognized as early as the pre-Qin period. In ancient times, the word "arthritis" was only used to describe symptoms. "Suwen Bi Lun Pian" is the earliest monograph on arthralgia discovered so far. It records: "The three qi of wind, cold and damp are mixed together, and they are combined to form arthralgia. Those who win the wind energy are walking arthralgia, and those who win the cold air are pain." Numbness, dampness wins for numbness." With the development of TCM theory, the concept of bone numbness is further separated from arthralgia. Unfavorable flexion and extension, or even swelling and burning of joints, ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/54A61P19/08A61P29/00A61K35/646A61K35/62A61K35/648
CPCY02A50/30
Inventor 韦佳佳陈涛李川赵晨阳甘吉明董卓谦张博南王京媛肖毕进
Owner 云南省中医医院
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