Pharmaceutical composition for treating child sexual precocity and application thereof

A technology of composition and medicine, which is applied in the field of traditional Chinese medicine, can solve the problems of expensive medicines, inability to prevent short stature, lower sex hormone levels, etc., and achieve the effect of short course of treatment, obvious effect and good curative effect

Pending Publication Date: 2022-04-12
江西省儿童医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the curative effect of GnRHa is certain, but generally it should be treated continuously for several months to several years, until it is close to the age of puberty, the drug price is expensive, and it will bring a great economic burden to the families of most children; progesterone ho

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0049] Recipe composition:

[0050] Huaishan medicine 15 grams, Poria 15 grams, Anemarrhena 10 grams, Scrophulariae 10 grams, Radix Paeoniae Rubra 10 grams, Rehmannia glutinosa 10 grams, Alisma alisma salt 10 grams, Prunella vulgaris 10 grams.

[0051] Preparation method: weigh the medicinal materials according to the above formula, add 300ml of water, decoct twice, and combine the obtained decoctions.

Embodiment 2

[0052] Embodiment 2: clinical treatment case

[0053] 1. Cases

[0054] All cases are outpatients of Jiangxi Provincial Children's Hospital in 2019, as follows:

[0055] Date of visit / name / ID number / date of visit / diagnosis result / name of medicine

[0056] 2019.6.1 / Tu Moumou / 10971731 / Precocious puberty / PT No. 1

[0057] 2019.6.1 / Li Moumou / 8600158024 / Precocious Puberty / PT No. 1

[0058] 2019.6.1 / Nie Moumou / 10559372 / Premature Puberty / PT No. 1

[0059] 2019.6.1 / Lei Moumou / 8600154587 / Breast hypertrophy / PT No. 1

[0060] 2019.6.1 / Jiang Moumou / 8600183846 / Precocious Puberty / PT No. 1

[0061] 2019.6.1 / Wan Moumou / 8600204309 / Precocious Puberty / PT No. 1

[0062] 2019.6.1 / Wu Moumou / 8600156598 / Obesity, Gynecomastia / PT No. 1

[0063] 2019.6.1 / Xiong Moumou / 10622757 / breast hypertrophy / PT No. 1

[0064] 2019.6.1 / Chen Moumou / 8600184039 / precocious puberty / PT No. 1

[0065] 2019.6.1 / Zhang Moumou / 101642203 / Premature Puberty / PT No. 1

[0066] 2019.6.1 / Hu Moumou / 101739588 / Premature Puberty / ...

Embodiment 3

[0160] Example 3 Diagnosis and treatment of No. 8600237081 patient

[0161] Date: 2019 / 6 / 28

[0162] The child developed bilateral breasts for several months. Previously in good health. The father is in good health, the mother is in good health, and there is no family history of disease.

[0163] In recent months, the patient found bilateral breast development, no tenderness, no accelerated growth, no vaginal discharge, clear mind, good spirits, no special face, no skin rash, no special heart and lung auscultation, and soft abdomen. Specialist examination: no acne, double breasts B2 stage, breast nucleus 0.5*0.5cm 2 , No areola bulge, areola no pigmentation, vulva no discharge, no pigmentation, pubic hair PH1 stage.

[0164] Diagnosed as precocious puberty.

[0165] Adopt the decoction gained in Example 1 (i.e. PT No. 1), take it warmly once in the morning and in the evening, 1 month is a course of treatment, and take 2 courses of treatment.

[0166] Date: 2019 / 6 / 29

[...

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PUM

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Abstract

The invention discloses a pharmaceutical composition for treating child sexual precocious puberty and application of the pharmaceutical composition. The pharmaceutical composition comprises the following traditional Chinese medicinal raw material components in parts by weight: 10-20 parts of common yam rhizome, 10-20 parts of poria cocos, 5-15 parts of salted rhizoma anemarrhenae, 5-15 parts of radix scrophulariae, 5-15 parts of red paeony root, 5-15 parts of radix rehmanniae recen, 5-15 parts of salted rhizoma alismatis and 5-15 parts of selfheal. The pharmaceutical composition provided by the invention has a very good curative effect on child sexual precocity, especially the child sexual precocity with the syndrome of liver depression and kidney yin deficiency, particularly has an obvious curative effect on child simple breast development, and has the advantages of good curative effect, short treatment course, thorough curative effect, no side effect and the like.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a pharmaceutical composition for treating precocious puberty in children, especially precocious puberty in children with syndrome of liver depression and kidney yin deficiency, and its application. Background technique [0002] With the improvement of living standard and educational level and the change of social environment, children's precocious puberty is increasing year by year. Because of its serious impact on children's height and psychological state, it has been paid more and more attention by the society. Child Precocious Puberty (CPP) is a common endocrine disease in children. It is an abnormal phenomenon of growth and development. An endocrine disorder in which sexual characteristics or menarche occurs before the age of 10 in girls. Precocious puberty can be divided into two types, namely true precocious puberty and false precocious puberty. The f...

Claims

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Application Information

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IPC IPC(8): A61K36/8964A61K9/08A61P5/04A61P5/24
Inventor 陶强杨玉
Owner 江西省儿童医院
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