Compound artemisia apiacea powder for chickens and preparation method thereof
A technology of compound Qinghao powder and Qinghao is applied in the directions of medical preparations with non-active ingredients, medical preparations containing active ingredients, pharmaceutical formulas, etc., which can solve the problems of poor reliability of experimental data and difficult control of pharmaceutical technology, etc. Achieve reproducible and process-controllable effects
Pending Publication Date: 2022-05-06
河南海汇药物研究有限公司
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[0005] The object of the present invention is to provide a compound Qinghao powder for chicken and its preparation method, so as to solve the problems of difficult control of the process of the medicament and poor reliability of the experimental data proposed in the background art
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[0026] The following will clearly and completely describe the technical solutions in the embodiments of the present invention with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only some, not all, embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the protection scope of the present invention.
[0027] see figure 1 , the present invention provides a technical solution: take 5 times the amount of the designed prescription, and theoretically obtain a finished product amount of 5000g, and verify it in ten batches by the following method.
[0028] For the preparation of coarse powder, take 31250g of the processed net medicinal material Artemisia annua, and grind it into coarse powder
[0029] The preparation of the extract was passed through a No. 2 siev...
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The invention discloses compound artemisia apiacea powder for chicken and a preparation method thereof, and the preparation method comprises the following steps: step 1, weighing a processed artemisia apiacea medicinal material, and crushing the artemisia apiacea medicinal material into coarse powder to prepare artemisia apiacea powder; 2, adding petroleum ether in batches; 3, filtering, combining extracting solutions, and recovering petroleum ether from filtrate; step 4, concentrating the extracting solution into paste under reduced pressure; 5, adding auxiliary materials, and uniformly mixing; 6, granulating after forming, and drying at low temperature; and 7, granulating and crushing to prepare the compound artemisia apiacea powder. And 8, packaging the product in a bag, and inspecting. And step 9, packaging and boxing after inspection is qualified, sending into a finished product warehouse to inspect the content of finished products, carrying out mass production after the finished products are qualified, designing 5 times of the amount of the prescription, verifying in ten batches, feeding according to 10 times of the prescription amount according to a process research result, carrying out pilot-scale research, and analyzing that technical data of three batches of pilot-scale products are consistent with a process refinement result. And judging the reproducibility of the process refinement result.
Description
technical field [0001] The invention belongs to the related technical field of veterinary drugs, and in particular relates to a compound Qinghao powder for chickens and a preparation method thereof. Background technique [0002] At present, the anti-coccidial drugs in the market are all chemical drugs, which have large adverse reactions and large residues, which bring certain physical effects to people. [0003] For this reason, the application number is CN202110301638.9 to provide a new process for making unilateral Qinghao powder for chicken, which relates to the technical field of veterinary medicine. The new process for making unilateral Qinghao powder for chicken includes the following steps: selecting the medicinal material of Artemisia annua, and coarsely pulverizing it; extracting the medicinal material of Artemisia annua, concentrating it under reduced pressure to form a paste, extracting three times, combining the extracts, and filtering , and then concentrate und...
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IPC IPC(8): A61K36/282A61K9/14A61K47/04A61P33/02
CPCA61K36/282A61K9/143A61P33/02A61K2236/35A61K2236/39A61K2236/51
Inventor 郭建钊郭宇鹏王娅娟
Owner 河南海汇药物研究有限公司