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Application of autism serum neuron-derived exosome marker CHRM1

A technology of CHRM1 and exosomes, which is applied in the application field of CHRM1, a neuron-derived exosome marker in autism, can solve the problems of long test time, difficulties, confusion of mental diseases, etc.

Pending Publication Date: 2022-05-10
XI AN JIAOTONG UNIV
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  • Summary
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Problems solved by technology

However, this diagnostic method has certain defects: first, clinicians need to be able to accurately grasp the objective medical history and fully understand the mental and psychological development of the child, otherwise it is easy to be confused with other mental diseases; It takes a year for the final diagnosis; finally, questionnaire surveys are difficult for children younger than 3 years old

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  • Application of autism serum neuron-derived exosome marker CHRM1
  • Application of autism serum neuron-derived exosome marker CHRM1
  • Application of autism serum neuron-derived exosome marker CHRM1

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Embodiment Construction

[0029] In order to enable those skilled in the art to better understand the solutions of the present invention, the following will clearly and completely describe the technical solutions in the embodiments of the present invention in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only It is an embodiment of a part of the present invention, but not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts shall fall within the protection scope of the present invention.

[0030] It should be noted that the terms "first" and "second" in the description and claims of the present invention and the above drawings are used to distinguish similar objects, but not necessarily used to describe a specific sequence or sequence. It is to be understood that the data so used are interchangeable under appropriate ...

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Abstract

The invention discloses an application of an autism serum neuron-derived exosome marker CHRM1, and belongs to the technical field of biological medicine, a human whole transcriptome chip and qRT-PCR (quantitative reverse transcription-polymerase chain reaction) example verification are combined to respectively detect and verify the CHRM1 highly expressed in ASD (acute serum death) serum NDEs (nuclear magnetic resonance imaging), and mRNA (messenger ribonucleic acid) can be used as a serum NDEs marker for autism diagnosis. The kit fills the blank of ASD biochemical diagnosis.

Description

technical field [0001] The invention belongs to the technical field of biomedicine, and in particular relates to the application of CHRM1, an autism serum neuron-derived exosome marker. Background technique [0002] Autistic spectrum disorder (ASD) is a kind of widespread neuropsychiatric disorder with onset in early childhood and characterized by social communication impairment and limited repetitive behavior. This type of disease seriously affects the social function of children and is one of the most important diseases that cause mental disabilities in preschool children, causing great mental and social burdens on patients, families and society. [0003] At present, the main basis for the diagnosis of autism is "Autism Diagnostic Interview (Revised Edition)" and "Autism Diagnosis Observation Procedure Sheet", as well as necessary psychological assessment, physical and nervous system tests, and some necessary auxiliary tests. However, this diagnostic method has certain de...

Claims

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Application Information

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IPC IPC(8): C12Q1/6883
CPCC12Q1/6883C12Q2600/158
Inventor 黄辰秦棪楠曹丽
Owner XI AN JIAOTONG UNIV
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