Design method of multi-type organ chip database

A technology of organ chip and design method, which is applied in the design field of multi-type organ chip database, and can solve the problems of not carefully analyzing data association, value, and data sharing.

Pending Publication Date: 2022-05-24
TIANJIN POLYTECHNIC UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] During the process of organ chip culture and experimentation, a large amount of experimental data will be generated, but in previous studies, researchers did not carefully analyze the relationship between the data, especially for different organ chip experiments. , due to the different experimental teams, the data was not shared, only the experimental results were valued
At the same time, there is currently no auxiliary tool on the market that can analyze the results of similar experiments done in the past online, analyze and compare your own design parameters with other experiments online, and then predict the results of your own organ chip experiments

Method used

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  • Design method of multi-type organ chip database
  • Design method of multi-type organ chip database
  • Design method of multi-type organ chip database

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Embodiment Construction

[0027] The present invention adopts the following technical solutions, a method for constructing a database including multiple types of organ chip data, the method for establishing a database requires four steps to complete, such as figure 1 shown.

[0028] The first step is to establish a collection of public information data tables, such as figure 2 It includes drug information related data tables (stores drug name, molecular formula, two-dimensional and three-dimensional structural formula, target protein, SMILE format expression, MOL2VEC code, etc., where target protein information needs to establish protein data table and target data table To express Drug Target Interaction, referred to as DTI related information), cell information related data table (storing cell line name, source, gene sequence, GENE2VEC code, etc.), bioscaffold material information related data table (storing molecular formula, structural formula, code, etc.) representation, etc.), data tables relate...

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Abstract

The patent mainly describes a method for constructing a database containing different organ chip data, and a plurality of different types of organ chip data are respectively liver chip data, heart chip data, intestine chip data, lung chip data, kidney chip data, brain chip data, skin chip data, skeleton chip data and the like. Meanwhile, the system also comprises some public information which can be used by various organ chip data, and the public information mainly comprises medicine information, cell information, material information, biological reagent information, organ chip model information, organ chip parameter configuration information and experimental result information. The database can provide more sufficient and more comprehensive data for various data analysis methods, including deep learning models and the like, applied to the field of organ chips.

Description

technical field [0001] The invention belongs to the field of the combination of biomedical engineering and computer technology. Through computer technology, database technology, artificial intelligence technology, etc., it is closely combined with the cutting-edge technology in the field of biomedical engineering, which is an organ chip, and the use of relational database construction technology is effective. It solved the key link of the combination of organ-on-a-chip and artificial intelligence-how to establish an organ-on-chip database. [0002] This patent mainly describes a database construction method including data on different organ chips, multiple different types of organ chip data, namely liver chip data, heart chip data, intestinal chip data, lung chip data, kidney chip data, and brain chip data. Data, skin chip data, bone chip data, etc., and also includes some public information that various organ chip data will use, mainly including drug information, cell informa...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G06F16/22G06F16/215G06F16/28G16H10/40G16B5/00G16B40/00G16B50/30
CPCG06F16/2282G06F16/215G06F16/285G16H10/40G16B5/00G16B40/00G16B50/30
Inventor 马欣林文斌
Owner TIANJIN POLYTECHNIC UNIV
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