Eluting equipment used in polypeptide production process and implementation method thereof

A production process and elution equipment technology, applied in cleaning methods and appliances, chemical instruments and methods, cleaning hollow objects, etc., can solve problems affecting efficiency, shutdown operations, etc., and achieve the effect of avoiding residue and improving elution efficiency

Active Publication Date: 2022-06-24
江苏汉肽生物医药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, the existing raw materials for polypeptide production need to undergo solid-liquid separation after being crushed, and then undergo acid hydrolysis. Personnel are required to discharge the crushed raw materials and then enter the solid-liquid separation. The discharge and collection are usually directly discharged from the bottom of the crushing equipment. However, part of the crushed residue will be adsorbed on the inner wall of the equipment, and personnel cleaning needs to shut down the operation, which affects the efficiency. Therefore, we propose an elution equipment used in the polypeptide production process and its implementation method

Method used

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  • Eluting equipment used in polypeptide production process and implementation method thereof
  • Eluting equipment used in polypeptide production process and implementation method thereof
  • Eluting equipment used in polypeptide production process and implementation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] see Figure 1-Figure 3 , a kind of elution equipment used in the process of polypeptide production in the figure, including a pulverizing cylinder 1, the top of the pulverizing cylinder 1 is threaded with a cylinder cover 2 with a through hole, and the cylinder cover 2 is rotatably arranged with a rotating The pipe 3 also includes a movable seat 4 installed on the outside of the rotating pipe 3 and a discharge plate 9 located at the bottom of the pulverizing cylinder 1. The outside of the movable seat 4 is fixed with a pulverizing blade 5, which is installed on the cylinder cover 2 The driving member 6 at the top, the driving member 6 is used for the rotation of the rotating tube 3, and the rotating tube 3 is provided with a fixed shaft 7, the top of the fixed shaft 7 is fixed with the cylinder cover 2 through a bracket, and the bottom The end is fixed with the inner wall of the bottom end of the pulverizing cylinder 1 through a support plate, a cleaning member 8 is ins...

Embodiment approach

[0049] In this scheme: an implementation method of an elution device used in a polypeptide production process, comprising the following steps:

[0050] S1. Clean the desired plants, and then throw them into the crushing cylinder 1;

[0051] S2. Drive the crushing leaves 5 in the crushing cylinder 1 through the driving member 6 to crush the plants;

[0052] S3. The bottom of the pulverizing cylinder 1 is opened by moving the discharge assembly 12, and then the inner wall of the pulverizing cylinder 1 is scraped by the cleaning member 8 to realize the removal of residual materials.

Embodiment 2

[0054] see Figure 11 , this embodiment further describes Example 1, the top of the adjusting rod 17 in the figure is provided with a rotation groove, and the fixed shaft 7 is located at the position of the rotating groove of the adjusting rod 17 to fix the limit ring 24, and the limit ring 24 is fixed. A compression spring 25 is installed between the position ring 24 and the bottom of the rotating groove;

[0055] It is worth noting that, after the support table 11 is opened, the adjustment rod 17 can have a downward force through the action of the compression spring 25, so that the retraction of the two limiting plates 20 is more convenient.

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PUM

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Abstract

The invention discloses elution equipment used in a polypeptide production process and an implementation method of the elution equipment, relates to the technical field of polypeptide elution equipment, and solves the problem that crushed materials are easy to remain during existing polypeptide elution treatment.The elution equipment comprises a crushing cylinder, a cylinder cover with a through hole is in threaded butt joint with the top end of the crushing cylinder, and a rotating pipe is rotatably inserted in the cylinder cover; crushing blades are fixed to the outer side of the moving seat; the driving part is mounted at the top end of the barrel cover; a fixed shaft is arranged in the rotating pipe; a cleaning part is mounted at the top end of the fixed shaft; existing elution equipment is optimized, through mutual cooperation of the designed cleaning part and the discharging and conveying assembly, the effects of automatically discharging plants after polishing and cleaning the inner wall of the barrel are achieved, material residues are avoided, manual cleaning of workers is not needed, and the elution efficiency is improved.

Description

technical field [0001] The invention relates to the technical field of polypeptide elution devices, in particular to an elution device used in the production process of polypeptides and an implementation method thereof. Background technique [0002] Peptide is a compound formed by linking α-amino acids together by peptide bonds, and it is also an intermediate product of protein hydrolysis. Polypeptide is a compound formed by α-amino acids linked together by peptide bonds, and it is also an intermediate product of protein hydrolysis. The compound formed by the dehydration and condensation of two amino acid molecules is called dipeptide, and there are also tripeptide, tetrapeptide, pentapeptide, etc. by analogy. Compounds usually formed by dehydration and condensation of three or more amino acid molecules can be called polypeptides. In the process of polypeptide production, multiple steps are needed to finally form the product. In the current production process, the plants a...

Claims

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Application Information

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IPC IPC(8): B08B9/087B08B9/093B08B13/00
CPCB08B9/087B08B9/093B08B13/00
Inventor 殷世清王雷朱永真
Owner 江苏汉肽生物医药有限公司
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