Sperm sorting bionic system and application

A bionic system and sperm technology, applied in the field of biomedicine, can solve problems such as low efficiency and inability to realize sperm sorting at the same time, and achieve the effect of ensuring activity

Pending Publication Date: 2022-07-29
郭景桓 +1
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  • Description
  • Claims
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Problems solved by technology

Among them, sperm sorting is an important step in artificial insemination, which can obtain high-viability sperm; however, in the prior art, it is not possible to simultaneously sort sperm with X chromosomes and sperm with Y chromosomes, and Most of them can only be screened one by one, and it is impossible to sort a large number of sperm at the same time, which is inefficient

Method used

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  • Sperm sorting bionic system and application
  • Sperm sorting bionic system and application
  • Sperm sorting bionic system and application

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Embodiment

[0034] In the prior art, the devices capable of sorting sperm carrying X and Y chromosomes are all separate devices, and only one sperm can be sorted at a time, and then the sorted sperm needs to be transferred for subsequent artificial in vitro experiments. However, in the process of transfer, it is likely to damage the activity of sperm and cause a lot of unnecessary losses. Considering these problems, the present invention provides a sperm sorting bionic system, which can realize the sorting of a large number of sperm, and at the same time In the same system with sperm sorting function, an area that can directly perform artificial in vitro fertilization is reserved to avoid transfer after sorting, and it can directly combine sperm with eggs when applied to artificial in vitro fertilization to ensure sperm motility and improve Success rate.

[0035] Attached to the manual Figure 1-7 As shown, the sperm sorting bionic system includes a substrate 6, a bionic fallopian tube f...

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Abstract

The invention discloses a sperm sorting bionic system, which comprises a bionic fallopian tube flow channel used for allowing sperms to flow therein, one end of the bionic fallopian tube flow channel is a flow channel inlet, the other end of the bionic fallopian tube flow channel is a flow channel terminal, and the bionic fallopian tube flow channel is used for placing at least one ovum so that the sperms can reach the flow channel terminal to be combined with the ovum; the bionic fallopian tube flow channel is fixed above the base; the electrode assembly is arranged between the bionic fallopian tube flow channel and the substrate and used for generating adsorption voltage, and sperms carrying X chromosomes can be adsorbed when the electrode assembly outputs the adsorption voltage. The electrode assembly is adopted, adsorption voltage is generated when sperms flow through the electrode assembly, a large number of sperms carrying different specific chromosomes can be screened, the sorted sperms can be allowed to be combined with ova at the flow channel terminal, high efficiency, rapidness and high accuracy are achieved, and the quality of the sperms cannot be damaged.

Description

technical field [0001] The invention relates to the technical field of biomedicine, in particular to a sperm sorting bionic system and application. Background technique [0002] Artificial in vitro fertilization refers to the technology in which sperm and eggs are fertilized in an artificially controlled environment outside the body. It is a high-tech technology that has been widely used and developed rapidly around the world in recent years. Infertility is important. Among them, sperm sorting is an important step in artificial insemination, which can obtain sperm with a high motility rate; however, in the prior art, it is not possible to simultaneously sort sperm with X chromosome and sperm with Y chromosome, and Most of them can only be screened one by one, and the sorting of a large number of sperm cannot be achieved at the same time, which is inefficient. [0003] Therefore, there is a need for a sperm sorting bionic system and application, which can quickly sort a lar...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12M1/42C12M1/00
CPCC12M21/06C12M23/20C12M35/02C12M47/04
Inventor 郭景桓陈泓谕陈佳琦罗珮芬陈文艺杨芸玮
Owner 郭景桓
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