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Method for preparing Chinese medicinal granule by ultramicropulverization technology

An ultra-fine pulverization technology, a technology of traditional Chinese medicine granules, which is used in pharmaceutical formulations, medical preparations containing active ingredients, and bulk transportation, etc., can solve the problem that the extraction process cannot achieve ideal results, increase production costs and energy consumption, and affect drugs. Dissolution and other problems, to achieve the effect of reducing equipment investment, increasing fineness, and increasing dissolution

Inactive Publication Date: 2006-05-17
李建立
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Problems solved by technology

[0002] Traditional Chinese medicine granules are one of the important dosage forms of traditional Chinese patent medicines. Since their appearance in the 1960s, they have developed steadily. The production process generally includes processes such as medicinal material processing, extraction, concentration, granulation, drying, granulation, and packaging. Steps, the processing steps of the medicinal materials in the above process steps are the most critical, which will directly affect the extraction effect. According to the prescription requirements, the medicinal materials are added into pieces and segments, and processed according to the law, ready to be weighed and prepared. Some medicinal materials containing more starch need Grinding into fine powder, the existing production process is far from meeting the above requirements, thus affecting the dissolution rate of the drug, making the extraction process unable to achieve the desired effect, seriously wasting medicinal materials, and increasing production costs and energy consumption

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  • Method for preparing Chinese medicinal granule by ultramicropulverization technology
  • Method for preparing Chinese medicinal granule by ultramicropulverization technology

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Embodiment Construction

[0018] The present invention will be further described below in conjunction with accompanying drawing:

[0019] Overall process of the present invention such as figure 1 As shown, the process includes the treatment, concentration, granulation, drying, and granulation of medicinal materials; the treatment process of medicinal materials is to inject the traditional Chinese medicine crushed into coarse particles and the air after freeze-drying into the superfine pulverizer The ultrafine Chinese medicine powder is made by high-speed airflow pulverization, and the above-mentioned ultrafine Chinese medicine powder is fully dissolved, soaked, and filtered with an appropriate amount of solvent.

[0020] The technical parameter of each processing step of the present invention is:

[0021] The particle diameter of the ultrafine Chinese medicine powder is 2500 mesh.

[0022] The operating temperature of the ultrafine pulverizer is 8°C.

[0023] The diameter of the coarse particles of ...

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Abstract

The invention belongs to a production method of traditional Chinese medicine granules, in particular to a method for preparing traditional Chinese medicine granules by ultrafine pulverization technology. Including the processing, concentration, granulation, drying and sizing of medicinal materials; the processing process of medicinal materials is to inject the crushed Chinese medicine into coarse particles and the air after freeze-drying into the superfine pulverizer and use high-speed airflow to pulverize it to make superfine Chinese medicine powder , the above-mentioned ultrafine Chinese medicine powder is fully dissolved, soaked, and filtered with an appropriate amount of solvent, and the particle diameter of the ultrafine Chinese medicine powder is 1250 mesh-25000 mesh. The invention solves the problems of low drug dissolution rate, unsatisfactory extraction process effect, serious waste of medicinal materials, increased production cost and energy consumption in the existing production process. With high fineness of medicinal materials, the dissolution rate of its active ingredients is fast, and the drug effect is increased, which can effectively improve the bioavailability of drugs and save valuable Chinese herbal medicine resources. Reduced equipment investment, reduced production costs and other advantages.

Description

technical field [0001] The invention belongs to a production method of traditional Chinese medicine granules, in particular to a method for preparing traditional Chinese medicine granules by ultrafine pulverization technology. Background technique [0002] Traditional Chinese medicine granules are one of the important dosage forms of traditional Chinese patent medicines. They have developed steadily since their appearance in the 1960s. The production process generally includes processing, extraction, concentration, granulation, drying, granulation, packaging and other processes of medicinal materials. Steps, the processing steps of the medicinal materials in the above process steps are the most critical, which will directly affect the extraction effect. According to the prescription requirements, the medicinal materials are added into pieces and segments, and processed according to the law, ready to be weighed and prepared. Some medicinal materials con...

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/00A61K9/16
Inventor 李建立王夕军李建英
Owner 李建立