Capsule of Chinese traditional medicine for treating thrombus

A technology of traditional Chinese medicine capsules and vascular embolism, which is applied in the field of pharmaceutical compositions for the treatment of vascular embolism, which can solve the problems of affecting the curative effect of drugs and low content of active ingredients, and achieve the effects of benefiting drug efficacy, avoiding side effects, and reducing the formation rate

Inactive Publication Date: 2006-05-31
SHANXI MAIDI PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In some literatures, earthworm extracts or astragalus extracts are also used, but the contents of fibrinolytic enzymes and earthworms in the earthworm extracts are very low, the impurities without thrombolytic effect are high, and the active ingredients are low will directly affect the efficacy of the drug

Method used

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Examples

Experimental program
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Effect test

Embodiment Construction

[0027] The traditional Chinese medicine capsule preparation for treating vascular embolism of the present invention is prepared from earthworm extract and astragalus extract.

[0028] The preparation process of extracting fibrinolytic enzyme and earthworm from earthworm:

[0029] Clean the fresh ground dragon, homogenize it with a tissue homogenizer, and then perform centrifugal treatment. After earthworm homogenization, the rotation speed of the first centrifugal treatment is 7000-9000 rpm, and the treatment time is 30 minutes; the supernatant is collected for acid denaturation, and sodium acetate solution is added to make the concentration of sodium acetate in the supernatant Reach 30-60 mol / L, leave it for 4-8 hours and then perform the second centrifugal treatment, the rotation speed is 10000-15000 rpm, the treatment time is 15 minutes, and the supernatant is collected after centrifugation.

[0030] Pass the collected supernatant through a medium pressure chromatography column...

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Abstract

A Chinese medicine in the form of capsules for treating vascular thrombus and decreasing blood viscosity is prepared from fresh earthworm and astragalus root through extracting their active components and proportionally mixing.

Description

Technical field [0001] The invention relates to a pharmaceutical composition for treating vascular embolism, in particular to a traditional Chinese medicine capsule preparation capable of clearing cerebral thrombosis and coronary thrombosis. Background technique [0002] At present, there are many literature reports on the use of traditional Chinese medicine to treat vascular embolism, involving a variety of prescriptions, dosage forms and different curative effects. Among them, the study of Astragalus and Dilong alone or the research involving Astragalus and Dilong in the prescription have also been reported, but in the preparation process, most of them use the method of decoction and water extraction, and the technology is backward. Especially when the earth dragon is processed and decocted, the active substances of protein and enzymes in its tissues have been destroyed, resulting in poor efficacy of the medicine. [0003] Modern studies have proved that the effective component...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/481A61K125/00A61K35/64A61K9/14A61K9/19A61K9/48A61P9/10A61P7/02A61K31/7048A61K35/62
Inventor 解军徐钧聂继盛于保锋胥显民陈显久黄登宇董华慧谭杏丽
Owner SHANXI MAIDI PHARMA
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