Bone powder of same bone and preparation method

A technology of bone powder and ultrasonic method, applied in medical science, prosthesis, etc., can solve the problems that the same kind of bone powder filling materials have not been seen, and cannot be made into large segments of bone.

Inactive Publication Date: 2006-06-28
山西奥瑞生物材料有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, none of the bone implant materials currently on the domestic market are human homogeneous bones, such as "Jinshi Zhiguling" (also known as "recombined heterogeneous bone") produced by Tianjin Zhongjin Pharmaceutical Co., Ltd. Biomedical Technology Branch, The "coral hydroxyapatite artificial bone" produced by Beijing Yihuajian Technology and Trade Co., Ltd. is not the same type of human bone, and it cannot be made into a large segment of bone in clinical treatment.
Moreover, in the clinical treatment of bone defects in the Department of Stomatology, there is no relevant information on the same kind of bone powder filling materials.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0013] The present invention will be described in more detail below by way of examples.

[0014] 1. Milling

[0015] 1.1 Rotate the cleaned cortical backbone into chips using a common lathe, and then put the chips into a miniature plant sample grinder to pulverize them to make bone meal;

[0016] 1.2 Use a block magnet to move and absorb iron powder particles that may be produced during the bone meal;

[0017] 1.3 Prepare one nylon mesh bag with a hole diameter of 0.9mm and 0.125mm, respectively screen out the powder particles with a particle size larger than 0.9mm and smaller than 0.125mm, and use the bone meal with a particle size between 0.125 and 0.9mm as raw materials for the next step process.

[0018] 2. Degreasing treatment

[0019] 2.1 Clean the pollutants. Take 300 grams of the prepared bone meal raw material and put it into a nylon mesh bag with a pore size of 0.125mm, put the nylon mesh bag into a stainless steel container containing 3000ml of distilled water, ...

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PUM

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Abstract

The invention is a homogeneous bone powder and its manufacturing method, which relates to filler for bone deficiency caused by several kinds of reasons in department of stomatology clinic treatment and its manufacturing method. The powder can be produced through crashing human bone into particle with particle size of 0.125-0.9mm, then carries on degreasing in distilled water and alcohol with supersonic method, then carries on mine eliminating in hydrochloric acid with supersonic method, following, eliminates the acid and adjusts the pH value, sterilization, finally freezes and dries, and irradiates them. It can reduce the immunogenicity, reserves adult bone factor, and kills pathogenetic microbe. It can be used as the fillers directly for bone deficiency caused by periodontal disease, dental extraction, cyst and tumor. It also can be processed into bone transplanting material with non-natural structure remolded with biology conciliator, in order to cure bone deficiency caused by other reasons.

Description

technical field [0001] The invention relates to an implant material for treating bone defects in orthopedic clinical medicine and a preparation method thereof, in particular to a homogeneous bone powder which can replace autologous bone for treatment and a preparation method thereof. Background technique [0002] At present, it is generally believed at home and abroad that orthopedic clinics use human homogeneous bone implant materials to replace autologous bone to treat bone defects caused by various reasons, such as bone fibrous dysplasia, giant cell tumor of bone, correction and fusion of scoliosis, bone defects caused by trauma and Segmental bone resection for bone tumors and bone grafting for limb salvage are both feasible and economical methods. However, none of the bone implant materials currently on the domestic market are human homogeneous bones, such as "Jinshi Zhiguling" (also known as "recombined heterogeneous bone") produced by Tianjin Zhongjin Pharmaceutical Co...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61L27/00
Inventor 李宝兴张康蓉邢力李幼忱李春源殷少芳石占城孙世荃
Owner 山西奥瑞生物材料有限公司
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